RubinTuderMD

PubMed

• Digital Spatial Profiling Identifies Distinct Molecular Signatures of Vascular Lesions in Pulmonary Arterial Hypertension.
  Aneta Gandjeva, Sarah Williams, Sushil Kumar, Vitaly O Kheyfets, Kyle Matthew Hatton-Jones, Jacqueline R Starr, Jason Hong, Nicholas P West, Rubin M Tuder, Jeong Yun, ...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Apr 3
• Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury.
  René M Roy, Ayed Allawzi, Nana Burns, Christina Sul, Victoria Rubio, Jessica Graham, Kurt Stenmark, Eva S Nozik, Rubin M Tuder, Christine U Vohwinkel> ;FASEB Journal. 2023 Dec 1
• 2 citations
  Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands.
  Daniela I Staquicini, Marina Cardó-Vila, Jimmy A Rotolo, Fernanda I Staquicini, Fenny H F Tang, Tracey L Smith, Aditya Ganju, Carmine Schiavone, Prashant Dogra, Zhihui...> ;Proceedings of the National Academy of Sciences of the United States of America. 2023 Aug 22
• 1 citations
  SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension.
  Min Li, Lydie Plecitá-Hlavatá, Evgenia Dobrinskikh, B Alexandre McKeon, Aneta Gandjeva, Suzette Riddle, Aya Laux, Ram Raj Prasad, Sushil Kumar, Rubin M Tuder, Hui Zhan...> ;American Journal of Respiratory Cell and Molecular Biology. 2023 Nov 1
• 2 citations
  Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension.
  Rahul Kumar, Michael H Lee, Biruk Kassa, Dara C Fonseca Balladares, Claudia Mickael, Linda Sanders, Adam Andruska, Maya Kumar, Edda Spiekerkoetter, Angela Bandeira, Ku...> ;Clinical Science. 2023 Apr 26
• The Effect of Hypoxia-inducible Factor Inhibition on the Phenotype of Fibroblasts in Human and Bovine Pulmonary Hypertension.
  Cheng-Jun Hu, Aya Laux, Aneta Gandjeva, Liyi Wang, Min Li, R Dale Brown, Suzette Riddle, Vitaly O Kheyfets, Rubin M Tuder, Hui Zhang, Kurt R Stenmark> ;American Journal of Respiratory Cell and Molecular Biology. 2023 Jul 1
• 16 citations
  Inhaled seralutinib exhibits potent efficacy in models of pulmonary arterial hypertension.
  Anna Galkin, Ravikumar Sitapara, Bryan Clemons, Eduardo Garcia, Michael Kennedy, David Guimond, Laura L Carter, Ashley Douthitt, Robin Osterhout, Aneta Gandjeva, Debor...> ;The European Respiratory Journal. 2022 Dec 1
• 4 citations
  Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension.
  Michael H Lee, Linda Sanders, Rahul Kumar, Daniel Hernandez-Saavedra, Xin Yun, Joshay A Ford, Mario J Perez, Claudia Mickael, Aneta Gandjeva, Daniel E Koyanagi, Julie ...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2022 Sep 1
• 3 citations
  The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension.
  Sue Gu, Claudia Mickael, Rahul Kumar, Michael H Lee, Linda Sanders, Biruk Kassa, Julie Harral, Jason Williams, Kirk C Hansen, Kurt R Stenmark, Rubin M Tuder, Brian B G...> ;Pulmonary Circulation. 2022 Jul 1
• 1 citations
  Peripheral Blood Inflammation Profile of Patients with Pulmonary Arterial Hypertension Using the High-Throughput Olink Proteomics Platform.
  Claudia Mickael, Vitaly O Kheyfets, Christophe Langouët-Astrié, Michael H Lee, Linda A Sanders, Caio O Trentin, Andrew J Sweatt, Roham T Zamanian, Todd M Bull, Kurt St...> ;American Journal of Respiratory Cell and Molecular Biology. 2022 May 1
• 3 citations
  Experimental Schistosoma japonicum-induced pulmonary hypertension.
  Biruk Kassa, Michael H Lee, Rahul Kumar, Claudia Mickael, Linda Sanders, Rubin M Tuder, Margaret Mentink-Kane, Brian B Graham> ;Plos Neglected Tropical Diseases. 2022 Apr 1
• 9 citations
  Matrix-Degrading Enzyme Expression and Aortic Fibrosis During Continuous-Flow Left Ventricular Mechanical Support
  Amrut V. Ambardekar, Matthew S. Stratton, Evgenia Dobrinskikh, Kendall S. Hunter, BS Philip D. Tatman, Madeleine E. Lemieux, Joseph C. Cleveland, Rubin M. Tuder, Mary ...> ;Journal of the American College of Cardiology. 2021 Nov 2
• 19 citations
  VEGF-C/VEGFR-3 signaling in macrophages ameliorates acute lung injury.
  Masahiro Yamashita, Miyuki Niisato, Yasushi Kawasaki, Sinem Karaman, Marius R. Robciuc, Yuji Shibata, Yoji Ishida, Ryosuke Nishio, Tomoyuki Masuda, Tamotsu Sugai, Masa...> ;The European Respiratory Journal. 2021 Aug 26
• 5 citations
  Endothelial cell PHD2-HIF1α-PFKFB3 contributes to right ventricle vascular adaptation in pulmonary hypertension.
  Biruk Kassa, Rajesh Kumar, Claudia Mickael, Linda Sanders, Christine Vohwinkel, Michael H. Lee, Sue Gu, Jens M. Poth, Kurt R. Stenmark, You Yang Zhao, Rubin M. Tuder, ...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2021 Aug 4
• 1 citations
  EXPRESS: Phosphoproteomic Analysis of Lung tissue from Patients with Pulmonary Arterial Hypertension:
  Ravikumar Sitapara, TuKiet T. Lam, Aneta Gandjeva, Rubin M. Tuder, Lawrence S. Zisman> ;Pulmonary Circulation. 2021 Jul 9
• 1 citations
  Bronchopulmonary Dysplasia: Endothelial Cells in the Driver's Seat.
  Christine U. Vohwinkel, Rubin M. Tuder> ;American Journal of Respiratory Cell and Molecular Biology. 2021 Jul 9
• 13 citations
  Targeting alveolar-specific succinate dehydrogenase A attenuates pulmonary inflammation during acute lung injury
  Christine U. Vohwinkel, Nana Burns, Hanan Elajaili, Daniel Hernandez‐Saavedra, Xiaoyi Yuan, Tobias Eckle, Eva Nozik, Rubin M. Tuder, Holger K. Eltzschig, Ethan J. Coit> ;FASEB Journal. 2021 Apr 1
• 15 citations
  Targeted Phage Display-based Pulmonary Vaccination in Mice and Non-human Primates.
  Daniela I. Staquicini, E. Magda Barbu, Rachel L. Zemans, Beth K. Dray, Fernanda I. Staquicini, Prashant Dogra, Marina Cardó-Vila, Cindy K. Miranti, Wallace B. Baze, Lu...> ;Med. 2021 Mar 12
• 26 citations
  Persistent, Progressive Pulmonary Fibrosis and Epithelial Remodeling in Mice
  Elizabeth F. Redente, Bart P. Black, Donald S. Backos, Ali N. Bahadur, Stephen M. Humphries, David A. Lynch, Rubin M. Tuder, Rachel L. Zemans, David W. H. Riches> ;American Journal of Respiratory Cell and Molecular Biology. 2021 Jun 1
• 8 citations
  Pathophysiology and potential future therapeutic targets using preclinical models of COVID-19
  Rajesh Kumar, Michael H. Lee, Claudia Mickael, Biruk Kassa, Qadar Pasha, Rubin M. Tuder, Brian B. Graham> ;ERJ Open Research. 2020 Oct 1
• 19 citations
  Platelet activation contributes to hypoxia-induced inflammation
  Cassidy Delaney, Pavel Davizon-Castillo, Ayed Allawzi, Janelle Posey, Aneta Gandjeva, Keith B. Neeves, Rubin M. Tuder, Jorge Di Paola, Kurt R. Stenmark, Eva Nozik> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2021 Mar 1
• 31 citations
  Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension
  Rajesh Kumar, Claudia Mickael, Biruk Kassa, Linda Sanders, Daniel Hernandez-Saavedra, Daniel E. Koyanagi, Sushil Kumar, Steve C Pugliese, Stacey M. Thomas, Jazalle McC...> ;Cardiovascular Research. 2020 Oct 1
• 20 citations
  Endothelial HIF-2α as a Key Endogenous Mediator Preventing Emphysema.
  Shravani Pasupneti, Wen Tian, Allen B. Tu, Petra Dahms, Eric J. Granucci, Aneta Gandjeva, Menglan Xiang, Eugene C. Butcher, Gregg L. Semenza, Rubin M. Tuder, Xinguo Ji...> ;American Journal of Respiratory and Critical Care Medicine. 2020 Oct 1
• 14 citations
  Epithelial cell-specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice.
  Hanh Chi Do-Umehara, Cong Chen, Qiao Zhang, Alexander V. Misharin, Hiam Abdala-Valencia, S. Marina Casalino-Matsuda, Paul A. Reyfman, Kishore R. Anekalla, Francisco J....> ;Science Advances. 2020 Aug 14
• 37 citations
  Localization of Macrophages in the Human Lung via Design-based Stereology.
  Patrick S. Hume, Sophie L. Gibbings, Claudia Jakubzick, Rubin M. Tuder, Douglas Curran-Everett, Peter M. Henson, Bradford J. Smith, William J. Janssen> ;American Journal of Respiratory and Critical Care Medicine. 2020 May 15
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Journal Articles

• TGF-Β Activation by Bone Marrow-Derived Thrombospondin-1 Causes Schistosoma- and Hypoxia-Induced Pulmonary Hypertension  
  William J Janssen, Jeffrey C Robinson, Rubin M Tuder, Kurt R Stenmark, Nature