RyanFlynnMDPhD

PubMed

• 4 citations
  Diverse functional elements in RNA predicted transcriptome-wide by orthogonal RNA structure probing.
  Dalen Chan, Chao Feng, Whitney England, Dana Wyman, Ryan A. Flynn, Xiuye Wang, Yongsheng Shi, Ali Mortazavi, Robert C. Spitale> ;Nucleic Acids Research. 2021 Nov 18
• 1 citations
  fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins.
  Meredith Corley, Ryan A. Flynn, Steven M. Blue, Brian A. Yee, Howard Y. Chang, Gene W. Yeo> ;STAR Protocols. 2021 Aug 25
• 182 citations
  Small RNAs are modified with N-glycans and displayed on the surface of living cells.
  Ryan A. Flynn, Kayvon Pedram, Stacy A. Malaker, Pedro J. Batista, Benjamin A. H. Smith, Alex G. Johnson, Benson M. George, Karim Majzoub, Peter W. Villalta, Jan E. Car...> ;Cell. 2021 Jun 10
• 106 citations
  Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
  Ryan A. Flynn, Julia A. Belk, Yanyan Qi, Yuki Yasumoto, Jin Wei, Mia Madel Alfajaro, Quanming Shi, Maxwell R. Mumbach, Aditi Limaye, Peter C DeWeirdt, Cameron O. Schmi...> ;Cell. 2021 Apr 29
• 13 citations
  Footprinting SHAPE-eCLIP Reveals Transcriptome-wide Hydrogen Bonds at RNA-Protein Interfaces.
  Meredith Corley, Ryan A. Flynn, Byron K. Lee, Steven M. Blue, Howard Y. Chang, Gene W. Yeo> ;Molecular Cell. 2020 Dec 3
• 15 citations
  Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells.
  Balyn W. Zaro, Joseph J. Noh, Victoria L. Mascetti, Janos Demeter, Benson M. George, Monika Zukowska, Gunsagar S. Gulati, Rahul Sinha, Ryan A. Flynn, Allison Banuelos,...> ;Elife. 2020 Nov 25
• 218 citations
  Progenitor identification and SARS-CoV-2 infection in human distal lung organoids.
  Ameen A. Salahudeen, Shannon S. Choi, Arjun Rustagi, Junjie Zhu, Vincent van Unen, Sean M. de la O, Ryan A. Flynn, Mar Margalef-Català, António J. M. Santos, Jihang Ju...> ;Nature. 2020 Nov 25
• 13 citations
  Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection
  Ryan A. Flynn, Julia A. Belk, Yanyan Qi, Yuki Yasumoto, Cameron O. Schmitz, Maxwell R. Mumbach, Aditi Limaye, Jin Wei, Mia Madel Alfajaro, Kevin R. Parker, Howard Y. C...> ;Biorxiv. 2020 Oct 6
• 26 citations
  Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures
  Ameen A. Salahudeen, Shannon S. Choi, Arjun Rustagi, Junjie Zhu, Sean M. de la O, Ryan A. Flynn, Mar Margalef-Català, António J. M. Santos, Jihang Ju, Arpit Batish, Vi...> ;Biorxiv. 2020 Jul 27
• 5 citations
  A memory of eS25 loss drives resistance phenotypes.
  Alex G. Johnson, Ryan A. Flynn, Christopher P. Lapointe, Yaw Shin Ooi, Michael L Zhao, Christopher M. Richards, Wenjie Qiao, Shizuka B. Yamada, Julien Couthouis, Aaron...> ;Nucleic Acids Research. 2020 Jul 27
• 31 citations
  RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells.
  , , , , , , , , , , , , , , , , , , > ;Nature Cell Biology. 2020 Mar 30
• 46 citations
  DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
  Zhengping Shao, Ryan A. Flynn, Jennifer L. Crowe, Yimeng Zhu, Jialiang Liang, Wenxia Jiang, Fardin Aryan, Patrick Aoude, Carolyn R. Bertozzi, Verna M Estes, Brian J. L...> ;Nature. 2020 Feb 26
• 21 citations
  Functional significance of U2AF1 S34F mutations in lung adenocarcinomas
  Mohammad Shahrokh Esfahani, Luke J. Lee, Young-Jun Jeon, Ryan A. Flynn, Henning Stehr, Angela B. Hui, Noriko Ishisoko, Eric J. Kildebeck, Aaron M. Newman, Scott V. Bra...> ;Nature Communications. 2019 Dec 13
• 67 citations
  An RNA-centric dissection of host complexes controlling flavivirus infection.
  Yaw Shin Ooi, Karim Majzoub, Ryan A. Flynn, Miguel A. Mata, Jonathan Diep, Jason Kenichi Li, Nicholas van Buuren, Neil G. Rumachik, Alex G. Johnson, Andreas S. Puschni...> ;Nature Microbiology. 2019 Aug 5
• 58 citations
  HiChIRP reveals RNA-associated chromosome conformation.
  Maxwell R. Mumbach, Jeffrey M. Granja, Ryan A. Flynn, Caitlin M. Roake, Ansuman T. Satpathy, Adam J. Rubin, Yanyan Qi, Zhaozhao Jiang, Shadi Shams, Bryan H. Louie, Jim...> ;Nature Methods. 2019 May 27
• 47 citations
  The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders
  Cheen Euong Ang, Qing Ma, Orly L. Wapinski, Shenghua Fan, Ryan A. Flynn, Qian Yi Lee, Bradley P. Coe, Masahiro Onoguchi, Victor Hipolito Olmos, Brian T. Do, Lynn Dukes...> ;Elife. 2019 Jan 10
• 12 citations
  Retraction Note: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions.
  Wendy Huang, Benjamin Thomas, Ryan A. Flynn, Samuel J. Gavzy, Lin Wu, Sangwon V. Kim, Jason A. Hall, Emily R. Miraldi, Charles Ng, Frank Rigo, Sarah Meadows, Nina R. M...> ;Nature. 2018 Oct 1
• 99 citations
  Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders
  Eliezer Calo, Bo Gu, Margot E. Bowen, Fardin Aryan, Antoine Zalc, Jialiang Liang, Ryan A. Flynn, Tomek Swigut, Howard Y. Chang, Laura D. Attardi, Joanna Wysocka> ;Nature. 2018 Jan 24
• 111 citations
  Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity
  Frederick M. Tomlin, Ulla I. M. Gerling-Driessen, Yi-Chang Liu, Ryan A. Flynn, Janakiram R. Vangala, Christian S. Lentz, Sandra Clauder-Muenster, Petra Jakob, William ...> ;ACS Central Science. 2017 Oct 25
• 302 citations
  Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements
  Maxwell R. Mumbach, Ansuman T. Satpathy, Evan A. Boyle, Chao Dai, Benjamin G. Gowen, Seung Woo Cho, Michelle L.T. Nguyen, Adam J. Rubin, Jeffrey M. Granja, Katelynn R....> ;Nature Genetics. 2017 Sep 25
• 121 citations
  Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.
  Ryan Flynn, Katelyn Paz, Jing Du, Dawn K. Reichenbach, Patricia A. Taylor, Angela Panoskaltsis-Mortari, Ante Vulic, Leo Luznik, K. MacDonald, Geoffrey R. Hill, Melanie...> ;Blood. 2016 Apr 28
• 243 citations
  The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity
  Deniz Simsek, Gerald C. Tiu, Ryan A. Flynn, Gun Woo Byeon, Kathrin Leppek, Adele F. Xu, Howard Y. Chang, Maria Barna> ;Cell. 2017 Jun 1
• 6 citations
  Comparative Analysis Reveals Furoyl in Vivo Selective Hydroxyl Acylation Analyzed by Primer Extension Reagents Form Stable Ribosyl Ester Adducts.
  Dalen Chan, Chao Feng, Yuran Zhen, Ryan A. Flynn, Robert C. Spitale> ;Biochemistry. 2017 Mar 21
• 58 citations
  Comparison of SHAPE reagents for mapping RNA structures inside living cells
  Byron Lee, Ryan A. Flynn, Anastasia Kadina, Jimmy K. Guo, Eric T. Kool, Howard Y. Chang> ;RNA. 2017 Feb 1
• 6 citations
  Novel Gene Expression Profile of Women with Intrinsic Skin Youthfulness by Whole Transcriptome Sequencing
  Jin Xu, Robert C. Spitale, Linna Guan, Ryan A. Flynn, Eduardo A. Torre, Rui Li, Inbar Raber, Kun Qu, Dale Kern, Helen Knaggs, Howard Y. Chang, Anne Lynn S. Chang> ;Plos One. 2016 Nov 9
• Join now to see all