SachdevPThomasMD

PubMed

• Sex-dependent Prognosis of Patients with Advanced Soft Tissue Sarcoma.
  Chen Jiang, Zheyang Zhang, Jeffrey Bien, Amanda Siy, Ninah Achacoso, Aleyda V Solorzano, Pamela Tse, Elaine Chung, Sachdev Thomas, Laurel A Habel, Zhou, M., Bui, N., G...> ;Clinical Cancer Research. 2024 Jan 17
• Validation of Immunotherapy Response Score as Predictive of Pan-solid Tumor Anti-PD-1/PD-L1 Benefit.
  Benjamin J Bulen, Nickolay A Khazanov, Daniel H Hovelson, Laura E Lamb, Marc Matrana, Mark E Burkard, Eddy Shih-Hsin Yang, William J Edenfield, Elizabeth Claire Dees, ...> ;Cancer Research Communications. 2023 Jul 1
• 2 citations
  Sex- and Co-Mutation-Dependent Prognosis in Patients with SMARCA4-Mutated Malignancies.
  Chen Jiang, Zheyang Zhang, Ninah Achacoso, Aleyda V Solorzano-Pinto, Pam Tse, Elaine Chung, Jennifer Marie Suga, Sachdev Thomas, Laurel A Habel, Pan, M.> ;Cancers. 2023 May 9
• 6 citations
  Gain-of-Function and Non-Gain-of-Function Mutations Are Associated With Differential Prognosis in Advanced Pancreatic Ductal Adenocarcinoma.
  Chen Jiang, Zheyang Zhang, Ninah Achacoso, Stacey Alexeeff, Aleyda V Solorzano, Pam Tse, Elaine Chung, Tilak Sundaresan, Jennifer Marie Suga, Sachdev Thomas, Laurel A ...> ;JCO Precision Oncology. 2023 May 1
• 6 citations
  Development and validation of an integrative pan-solid tumor predictor of PD-1/PD-L1 blockade benefit.
  Tomlins, S., Khazanov, N., Bulen, B., Hovelson, D., Shreve, M., Lamb, L., Matrana, M., Burkard, M., Yang, E., Edenfield, W., Dees, E., Onitilo, A., Thompson, M., Buchs...> ;Communications Medicine. 2023 Feb 7
• 3 citations
  Improving Time to Molecular Testing Results in Patients With Newly Diagnosed, Metastatic Non-Small-Cell Lung Cancer.
  Stephanie Ossowski, Elad Neeman, Charles Borden, Douglas Stram, Lucy Giraldo, Dinesh Kotak, Sachdev Thomas, J Marie Suga, Amy Lin, Raymond Liu> ;JCO Oncology Practice. 2022 Nov 1
• 20 citations
  TP53 Gain-of-Function and Non–Gain-of-Function Mutations Are Differentially Associated With Sidedness-Dependent Prognosis in Metastatic Colorectal Cancer
  Chen Jiang, Pam Tse, Ninah Achacoso, Stacey E. Alexeeff, Aleyda V Solorzano, Elaine Chung, Wenwei Hu, Thach-Giao Truong, Amit Arora, Tilak Kumar Sundaresan, Jennifer M...> ;Journal of Clinical Oncology. 2021 Nov 29
• 8 citations
  Phase 2 multicentre study of single-agent ofatumumab in previously untreated follicular lymphoma: CALGB 50901 (Alliance).
  Sin-Ho Jung, Brandelyn N. Pitcher, Nancy L. Bartlett, Sonali M. Smith, Eric D. Hsi, Nina D. Wagner-Johnston, Sachdev P. Thomas, John P. Leonard, Bruce D. Cheson> ;British Journal of Haematology. 2019 Apr 1
• 4 citations
  Multi-Institutional, Prospective Clinical Utility Study Evaluating the Impact of the 92-Gene Assay (CancerTYPE ID) on Final Diagnosis and Treatment Planning in Patient...
  Sachdev P. Thomas, Lauren E. Jacobson, Anthony R. Victorio, Theresa N. Operana, Brock Schroeder, Catherine A. Schnabel, Fadi Braiteh> ;JCO Precision Oncology. 2018 Mar 5
• 54 citations
  Phase III Randomized, Placebo-Controlled, Double-Blind Trial of Celecoxib in Addition to Standard Chemotherapy for Advanced Non-Small-Cell Lung Cancer With Cyclooxygen...
  Martin J. Edelman, Xiaofei Wang, Lydia Hodgson, Richard T. Cheney, Maria Q. Baggstrom, Sachdev P. Thomas, Ajeet Gajra, Erin M. Bertino, Karen L. Reckamp, Julian R. Mol...> ;Journal of Clinical Oncology. 2017 May 10
• 6 citations
  "Enjoy glass of wine before eating:" a randomized trial to test the orexigenic effects of this advice in advanced cancer patients.
  Aminah Jatoi, Rui Qin, Daniel Satele, Shaker R. Dakhil, Pankaj Kumar, David B. Johnson, Sachdev P. Thomas, Philip J. Stella, Jose Castillo, Min Li, Martin E. Fernandez...> ;Supportive Care in Cancer. 2016 Apr 2
• 17 citations
  Concurrent EGFR Mutation and ALK Translocation in Non-Small Cell Lung Cancer
  Randy F. Sweis, Sachdev Thomas, Bruce Bank, Paul A. S. Fishkin, Colin Mooney, Ravi Salgia> ;Cureus. 2016 Feb 26
• 106 citations
  Chemotherapy With or Without Maintenance Sunitinib for Untreated Extensive-Stage Small-Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Phase II Study—...
  Neal Ready, Herbert Pang, Lin Gu, Gregory A. Otterson, Sachdev P. Thomas, Antonius A. Miller, Maria Q. Baggstrom, Gregory A. Masters, Stephen L. Graziano, Jeffrey Craw...> ;Journal of Clinical Oncology. 2015 May 20
• 31 citations
  A Phase I/II Study of Bortezomib in Combination with Paclitaxel, Carboplatin, and Concurrent Thoracic Radiation Therapy for Non–Small-Cell Lung Cancer: North Central C...
  Yujie Zhao, Nathan R. Foster, Jeffrey P. Meyers, Sachdev P. Thomas, Donald W. Northfelt, Kendrith M. Rowland, Bassam I. Mattar, David B. Johnson, Julian R. Molina, Sum...> ;Journal of Thoracic Oncology. 2015 Jan 1
• 7 citations
  NCCTG N0821 (Alliance): a phase II first-line study of pemetrexed, carboplatin, and bevacizumab in elderly patients with advanced nonsquamous non-small-cell lung cance...
  Grace K. Dy, Julian R. Molina, Yingwei Qi, Rafat Ansari, Sachdev P. Thomas, Helen J. Ross, Gamini S. Soori, Marie Christine Aubry, Jeffrey P. Meyers, A. A. Adjei, Sumi...> ;Journal of Thoracic Oncology. 2014 Aug 1
• 90 citations
  Phase II Study of the Oral MEK Inhibitor Selumetinib in Advanced Acute Myelogenous Leukemia: A University of Chicago Phase II Consortium Trial
  Nitin Jain, Emily Curran, Neil M. Iyengar, Ernesto Diaz-Flores, Rangesh Kunnavakkam, Leslie Popplewell, Mark Kirschbaum, Theodore Karrison, Harry P. Erba, Margaret Gre...> ;Clinical Cancer Research. 2014 Jan 15
• 45 citations
  Cediranib in patients with malignant mesothelioma: a phase II trial of the University of Chicago Phase II Consortium.
  Nicholas P. Campbell, Rangesh Kunnavakkam, Natasha B. Leighl, Mark Vincent, David R. Gandara, Marianna Koczywas, Barbara J. Gitlitz, Edem Agamah, Sachdev P. Thomas, Wa...> ;Lung Cancer. 2012 Oct 1
• 44 citations
  Placebo-Controlled Trial to Determine the Effectiveness of a Urea/Lactic Acid–Based Topical Keratolytic Agent for Prevention of Capecitabine-Induced Hand-Foot Syndrome...
  Sherry L. Wolf, Rui Qin, Smitha Menon, Kendrith M. Rowland, Sachdev P. Thomas, Robert Delaune, Diana Christian, Eduardo R. Pajon, Daniel Satele, Jeffrey L. Berenberg, ...> ;Journal of Clinical Oncology. 2010 Dec 10
• 78 citations
  A phase II trial of Triapine® (NSC# 663249) and gemcitabine as second line treatment of advanced non-small cell lung cancer: Eastern Cooperative Oncology Group Study 1503
  Anne M. Traynor, Ju Whei Lee, Gerald Bayer, John M. Tate, Sachdev P. Thomas, Miroslaw Mazurczak, David L. Graham, Jill M. Kolesar, Joan H. Schiller> ;Investigational New Drugs. 2010 Feb 1
• 199 citations
  Carboplatin and Paclitaxel in Combination With Either Vorinostat or Placebo for First-Line Therapy of Advanced Non–Small-Cell Lung Cancer
  Suresh S. Ramalingam, Michael L. Maitland, Paul Frankel, Athanassios Argiris, Marianna Koczywas, Barbara J. Gitlitz, Sachdev P. Thomas, Igor Espinoza-Delgado, Everett ...> ;Journal of Clinical Oncology. 2010 Jan 1
• 3 citations
  Phase I adjuvant radiation with docetaxel in high-risk head and neck cancer.
  Joseph I. Clark, Robert M. Eisner, Craig C. Hofmeister, John Norton, Sachdev P. Thomas, Abdul Choudhury, Guy J. Petruzzelli, Deanne M. R. Lathers, M. Rita I. Young, An...> ;American Journal of Clinical Oncology. 2009 Aug 1
• 69 citations
  Phase III randomized, placebo-controlled, double-blind trial of risedronate for the prevention of bone loss in premenopausal women undergoing chemotherapy for primary ...
  Stephanie L. Hines, Betty A. Mincey, Jeff A. Sloan, Sachdev P. Thomas, Elaine Chottiner, Charles L. Loprinzi, Mark D. Carlson, Pamela J. Atherton, Muhammad Salim, Edit...> ;Journal of Clinical Oncology. 2009 Mar 1
• 25 citations
  Bortezomib, Paclitaxel, and Carboplatin as a First-Line Regimen for Patients with Metastatic Esophageal, Gastric, and Gastroesophageal Cancer: Phase II Results from th...
  Aminah Jatoi, Shaker R. Dakhil, Nathan R. Foster, Cynthia X. Ma, Kendrith M. Rowland, Dennis F. Moore, Anthony J. Jaslowski, Sachdev P. Thomas, Mark D. Hauge, Patrick ...> ;Journal of Thoracic Oncology. 2008 May 1
• 23 citations
  A University of Chicago consortium phase II trial of SB-715992 in advanced renal cell cancer.
  Richard T. Lee, Kathleen E. Beekman, Maha Hussain, Nancy B. Davis, Joseph I. Clark, Sachdev P. Thomas, Katherine F. Nichols, Walter M. Stadler> ;Clinical Genitourinary Cancer. 2008 Mar 1
• ECOG 1503: A phase II trial of triapine (NSC#663249) with gemcitabine (T/G) as 2nd line treatment of non-small cell lung cancer (NSCLC).
  Traynor AM, Levy DE, Bayer GK, Tate JM, Thomas SP, Mazurczak MA, Graham DL, Kolesar JM, Schiller JH> ;J. Clin. Oncol.. 2006-06-20
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Journal Articles

• Carboplatin and Paclitaxel in Combination with Either Vorinostat or Placebo for First-Line Therapy of Advanced Non-Small Cell Lung Cancer.  
  Ramalingam SS, Maitland ML, Frankel P, Argirls AE, Koczywas M, Gitiltz B, Thomas S, Espinoza-Delgado I, Vokes EE, Gandara DR, Belani CP, JCO, 1/1/2010
• A University of Chicago consortium phase II trial of SB-715992 in advanced renal cell cancer.  
  Lee RT, Beekman KE, Hussain M, Davis NB, Clark JI, Thomas SP, Nichols KF, Stadler WM, Clin Genitourin Cancer, 3/1/2008
• "Randomized Phase II Trial of Erlotinib or Standard Chemotherapy in Patients With Advanced Non-Small-Cell Lung Cancer and a Performance Status of 2".  
  Lilenbaum R, Axelrod R, Thomas S, Dowlati A, Seigel L, Albert D, Witt K, Botkin D, JCO, 2/20/2008
• "Randomized Phase II Trial of Three Schedules of Pemetrexed and Gemcitabine As Front-Line Therapy for Advanced Non-Small-Cell Lung Cancer".  
  Ma CX, Nair S, Thomas S, Mandrekar SJ, Nikcevich DA, Rowland KM, Fitch TR, Windschitl HE, Hillman SL, Schild SE, Jett JR, Obasaju C, Adjei AA; North Central Cancer Tre..., JCO, 9/1/2005
• "Mortality associated with daily bolus 5-fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin: results from Intergroup Trial N9741".  
  Delaunoit T, Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Findlay BP, Thomas SP, Salim M, Schaefer PL, Stella PJ, Green E, Mailliard JA, Cancer, 11/15/2004
• "Genomic Organization and Refined Mapping of the Human Nuclear Corepressor 2 (NCOR2)/ Silencing Mediator of Retinoid and Thyroid Hormone Receptor (SMRT) Gene on Chromo...  
  Jiang Q, Galiegue-Zouitina S, Roumier C, Hildebrand MP, Thomas S, Coignet LJ, Cytogenet Cell Genet, 1/1/2001
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Abstracts/Posters

• "A Phase I Trial of Adjuvant Radiochemotherapy Using Docetaxel for Resectable High Risk Squamous Cell Carcinoma (SCC) of the Head and Neck".
  Hofmeister C, Lau-Schwabe A, Petruzzelli G, Emami B, Thomas S, Clark JI, Lung Cancer
• "Cediranib in patients with malignant mesothelioma: A phase II trial of the University of Chicago Phase II Consortium".
  Campbell NP, Kunnavakkam R, Leighl N, Vincent MD, Gandara DR, Koczywas M, Gitlitz BJ, Agamah E, Thomas SP, Stadler WM, Vokes EE, Kindler HL, Lung Cancer, 10/1/2012
• "MAVERICC: A randomized phase II study of mFOLFOX6-bevacizumab (BV) versus FOLFIRI-BV with prospective biomarker stratification in previously untreated metastatic co...
  Thomas SP, Badarinath S, Greenberg RH, Huh SY, Sivarajan KM, Feng S, Scherer S, Curry CL, Langer C, Lenz HJ, J Clin Oncol, 5/20/2012
• "Phase I trial of temsirolimus and lenalidomide in patients with rel/ref lymphomas".
  Smith SM, Cohen KS, Kline JP, Zavala JD, Conner K, Thomas SP, Lesho P, Doyle LA, Stadler WM, Karrison T, Kimball AS, J Clin Oncol, 5/20/2012
• "N0821: A phase II first-line study of a combination of pemetrexed (P), carboplatin ©, and bevacizumab (B) in elderly patients with good performance status (PS < 2)".
  Dy GK, Molina JR, Qi Y, Ansari RH, Thomas SP, Ross HJ, Meyers JP, Adjei A, Mandrekar SJ, Adjei AA, J Clin Oncol, 5/20/2012
• "N0321: A phase II study of bortezomib, paclitaxel, carboplatin (CBCDA), and radiotherapy (RT) for locally advanced nonsmall cell lung cancer (NSCLC)".
  Schild SE, Foster NR, Molina JR, Dy GK, Rowland KM, Sarkaria JN, Thomas SP, Northfelt DW, Kugler JW, Adjei AA, J Clin Oncol, 5/20/2012
• "A phase IB/randomized phase II study of gemcitabine (G) plus placebo (P) and vismodegib (V), a hedgehog (Hh) pathway inhibitor, in patients (pts) with metastatic panc...
  Catenacci DVT, Bahary N, Edelman MJ, Nattam SR, Marsh R, Kaubisch A, Wallace JA, Cohen DJ, Stiff PJ, Sleckman BG, Thomas SP, Lenz HJ, Henderson L, Zagaya C, Vannier M,..., J Clin Oncol, 5/20/2012
• "Connect MM: The multiple myeloma (MM) disease registry - Incidence of second primary malignancies (SPM)".
  Rifkin RM, Abonour R, Fonseca R, Gasparetto C, Mehta J, Narang M, Pashos CL, Thomas SP, Shah JJ, Terebelo HR, Toomey K, Minton N, Srinivasan S, Street T, Sullivan K, D..., J Clin Oncol, 5/20/2012
• "Cediranib (C) in patients (pts) with malignant mesothelioma (MM): A phase II trial of The University of Chicago Phase II Consortium".
  Campbell NP, Kunnavakkam R, Leighl NB, Vincent MD, Gandara DR, Koczywas M, Gitlitz BJ, Agamah ES, Thomas SP, Stadler WM, Vokes EE, Kindler HL, J Clin Oncol, 1/1/2011
• "30 Day Mortality of Right Lobectomy Versus Right Pneumonectomy for Curative Resection of Non-Small Cell Lung Cancer".
  Thomas SP, Mueller D, Anderson R, Wang H, Follies S, Illinois CancerCare, Peoria, IL; Heart Care Midwest, Peoria, IL; UICOMP, Department of Medicine, Peoria, IL; OSF S..., Chicago Thoracic Oncology Symposium, 12/9/2010
• "Incidence of febrile neutropenia in lymphoma patients receiving CHOP with Day 1 or 2 pegfilgrastim".
  Woods MA, Lopez T, Thomas SP, Harwood H, Kettler SM, J Clin Oncol 28, 1/1/2010
• "The prognostic significance of immunohistochemical (IHC) staining of the sentinal lymph node (SNL) in breast cancer patients".
  Thomas SP, Sood N, Wang H, Williams N, Graumlich JF, J Clin Oncol 28, 1/1/2010
• "Placebo-Controlled Trial to Determine the Effectiveness of a Ure/Lactic Acid-Based Topical Keratolytic Agent for Prevention of Capecitabine-Induced Hand-Foot Syndrome...
  Wolf SL, Qin R, Menson SP, Rowland KM, Thomas, S, Delaune R, Christian D Pajon ER, Satele DV, Berenberg JL, Loprinzi CL, J Clin Oncol, 1/1/2010
• "N0321: A phase I study of bortezomib, paclitaxel, carboplatin (CBDCA), and radiotherapy (RT) for locally advanced non-small cell lung cancer (NSCLC)". (Poster Discuss...
  Schild SE, Molina JR, Dy GK, Rowland KM, Sakaria JN, Thomas SP, Northfelt DW, Kugler JW, Foster NR, Adjei AA, J Clin Oncol, 1/1/2010
• "Incidence of febrile neutropenia (FN) with pegfilgatim (PF) on day of chemotherapy (D1) versus 24-72 hours later (D2)".
  Kumar P, Ingle AM, Miller S, Woods M, Thomas SP, Children’s JCO, 1/1/2009
• "Phase II Study of the Oral MEK Inhibitor AZD6244 in Advanced Acute Myeloid Leukemia (AML)".
  Odenike O, Curran E, Iyengar N, Popplewell L, Kirschbaum M, Erba HP, Green M, Poire X, Ihonor P, Diaz-Flores E, Shannon K, Atallah E, Wade JL, Perdekamp M, Nattam S, T..., Proc 51st Annu Meet Am Soc Hema, 1/1/2009
• "Impact of number of lymph nodes (LN) examined at the time of surgical resection (Sx) on the survival of stage IA non-small cell lung cancer (NSCLC) patients (pts)."
  Ingle M, Kumar P, Griggs MM, Erangey CA, Thomas SP, Proc Annu Meet Am Soc Clin Oncol, 1/1/2008
• "N02C1: A phase III randomized, placebocontrolled, double-blind trial of risedronate for prevention of bone loss in premenopausal women undergoing adjuvant chemotherap...
  Hines SL, Mincey BA, Sloa JA, Thomas SP, Chottiner EG, Loprinz CL, Atherton PJ, Carlson MD, Salim M, Perez EA, Proc Annu Meet Am Soc Clin Oncol, 1/1/2008
• "University of Chicago Consortium phase II study of ispinesib (SB-715992) in patients (pts) with advanced renal cell carcinoma (RCC)".
  Beekman KW, Dunn R, Colevas D, Davis N, Clark J, Agamah E, Thomas S, Nichols K, Redman B, Stadler W, Proc Annu Meet Am Soc Clin Oncol Part I, 1/1/2007
• Randomized Phase II Trial of Single Agent Erlotinib vs. Standard Chemotherapy in Patients With Advanced Non-Small Cell Lung Cancer and Performance Status of 2.
  Lilebaum R, Axerold R, Thomas S, Dowlati A, Seigel L, Albert D, Van Duym C, Bodkin D, Proc Ann Meet Am Soc Clin Oncol, 1/1/2006
• "ECOG 1503: A Phase II Trial of Triapine with Gemcitabine as 2nd Line Treatment of Non-Small Cell Lung Cancer".
  Traynor AM, Levy DE, Bayer GK, Tate JM, Thomas SP, Maruczarak MA, Graham DL, Kolesar JM, Schiller JH, Proc Annu Meet Am Soc Clin Oncol, 1/1/2006
• "Phase II Study of Bortezomib in Advanced or Metastatic Urothelial Cancer: A Trial of the Princess Margaret Hospital Phase II Consortium".
  Sridhar SS, Stadler W, Le E, Hedley D, Pond G, Wright J, Vokes E, Thomas S, Moore M, Proc Ann Meet Am Soc Clin Oncol, 1/1/2005
• "CD10 Detection by Flow Cytometry as a Prognostic Marker in de Novo Diffuse Large B-Cell Lymphoma".
  Siebert JD, Weeks LM, Sun J, Knost JA, Fishkin PAS, Thomas SP, Kugler JW, Am J Clin Path, 1/1/2002
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Lectures

• "MAVERICC: A randomized phase II study of mFOLFOX6-bevacizumab (BV) versus FOLFIRI-BV with prospective biomarker stratification in previously untreated metastatic co... 
  2012 ASCO Annual Meeting - 1/1/2012
• "Phase I trial of temsirolimus and lenalidomide in patients with rel/ref lymphomas". 
  2012 ASCO Annual Meeting - 1/1/2012
• "N0821: A phase II first-line study of a combination of pemetrexed (P), carboplatin ©, and bevacizumab (B) in elderly patients with good performance status (PS < 2)". 
  2012 ASCO Annual Meeting - 1/1/2012
• "N0321: A phase II study of bortezomib, paclitaxel, carboplatin (CBCDA), and radiotherapy (RT) for locally advanced nonsmall cell lung cancer (NSCLC)". 
  2012 ASCO Annual Meeting - 1/1/2012
• "A phase IB/randomized phase II study of gemcitabine (G) plus placebo (P) and vismodegib (V), a hedgehog (Hh) pathway inhibitor, in patients (pts) with metastatic panc... 
  2012 ASCO Annual Meeting - 1/1/2012
• "Connect MM: The multiple myeloma (MM) disease registry - Incidence of second primary malignancies (SPM)". 
  2012 ASCO Annual Meeting - 1/1/2012
• "Cediranib (C) in patients (pts) with malignant mesothelioma (MM): A phase II trial of The University of Chicago Phase II Consortium". 
  2011 ASCO Annual Meeting - 1/1/2011
• "Incidence of febrile neutropenia in lymphoma patients receiving CHOP with Day 1 or 2 pegfilgrastim". 
  2010 ASCO Annual Meeting - 1/1/2010
• "The prognostic significance of immunohistochemical (IHC) staining of the sentinal lymph node (SNL) in breast cancer patients". 
  2010 ASCO Annual Meeting - 1/1/2010
• "Placebo-Controlled Trial to Determine the Effectiveness of a Ure/Lactic Acid-Based Topical Keratolytic Agent for Prevention of Capecitabine-Induced Hand-Foot Syndrome... 
  2010 ASCO Annual Meeting - 1/1/2010
• "Incidence of febrile neutropenia (FN) with pegfilgatim (PF) on day of chemotherapy (D1) versus 24-72 hours later (D2)". 
  Illinois CancerCare, Peoria, IL - 1/1/2009
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