Samantha E Meltzer-Brody MD
Executive Dean, UNC School of Medicine Assad Meymandi Distinguished Professor and Chair, UNC Department of Psychiatry, Director UNC Center for Women's Mood Disorders
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CB 7160Chapel Hill, NC 27599
Phone+1 919-966-5217
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Summary
- Samantha Meltzer-Brody, MD, MPH is a psychiatry specialist based in Chapel Hill, NC, who became the Executive Dean of the UNC School of Medicine in 2025. She served as the Assad Meymandi Distinguished Professor and Chair of the Department of Psychiatry at University of North Carolina Hospitals from October 2019-March 2025. Dr. Meltzer-Brody completed her medical education at Northwestern University The Feinberg School of Medicine in 1996 and her psychiatry residency at Duke University Hospital in 2000. Dr. Meltzer-Brody's expertise covers women's health, depressive disorders, post-partum depression, and women's reproductive mood disorders. She has published widely and has been involved in several pivotal clinical trials focused on postpartum depression.
Education & Training
Duke University HospitalResidency, Psychiatry, 1996 - 2000
Northwestern University The Feinberg School of MedicineClass of 1996
Certifications & Licensure
MI State Medical License 2022 - 2028
CO State Medical License 2022 - 2027
IN State Medical License 2022 - 2027
NJ State Medical License 2023 - 2027
NV State Medical License 2023 - 2027
WV State Medical License 2023 - 2027
AZ State Medical License 2023 - 2026
American Board of Psychiatry and Neurology Psychiatry- Join now to see all
Awards, Honors, & Recognition
- Sanders Clinician Scholar UNC, 2012
Clinical Trials
- Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression Start of enrollment: 2012 Nov 01
- Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition Start of enrollment: 2013 Aug 01
- Study of Exposure to Stress, Postpartum Mood, Adverse Life Events, and Hormonal Function Among Latinas (SEPAH Latina) Start of enrollment: 2013 Aug 01
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Publications & Presentations
PubMed
- Characterizing the spectrum of distress symptoms in midlife women with perimenopausal depression.Margo D Nathan, Erin Bondy, Julianna Prim, Kathryn Gibson, David R Rubinow
Journal of Affective Disorders. 2026-01-01 - Open-label study of the efficacy, safety and tolerability of Brexanolone in the treatment of adult women with postpartum psychosis.Riah Patterson, Holly Krohn, Elizabeth Richardson, Cecilia Pearson, Kai Xia
General Hospital Psychiatry. 2025-11-03 - Identification and validation of postpartum depression subtypes: a population-based cohort study.Anna E Bauer, Piotr Jaholkowski, Yi Lu, Jerry Guintivano, Laurie J Hannigan
Eclinicalmedicine. 2025-11-01
Authored Content
- F124. PPD ACT, an App-Based Postpartum Depression Genetic StudyApril 2018
- F124. PPD ACT, an App-Based Postpartum Depression Genetic StudyApril 2018
- S100. Efficacy and Safety of Brexanolone IV Across Phase 2/3 Studies: A First-in-Class GABAA Receptor Positive Allosteric Modulator for Postpartum DepressionApril 2018
Press Mentions
Ferris, Meltzer-Brody Elected to National Academy of MedicineOctober 20th, 2025- UNC Physicians Develop Fast Treatment to Ease Depression in Pregnant and Postpartum WomenSeptember 9th, 2025
- Behavioral Activation Therapy Reduces Suicide Ideation in Perinatal Depression, Regardless of Provider TypeAugust 20th, 2025
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Grant Support
- HPA Stress Reactivity &Genetic Influences In Postpartum DepressionNational Institute Of Mental Health2009–2012
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