Samir R Kapadia MD

Interventional Cardiology

Chairman, Department of Cardiovascular Medicine, Cleveland Clinic.

9500 Euclid AveCleveland, OH 44195
Phone+1 800-223-2273

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Summary

Dr. Samir Kapadia is a cardiologist specializing in Interventional Cardiology, based in Cleveland, OH. He completed his fellowship in cardiovascular disease at Cleveland Clinic Foundation and his residency in Internal Medicine at Baylor College of Medicine. Dr. Kapadia has notable experience in pericardiocentesis, coronary artery disease, myocardial infarction, ischemic cardiomyopathy, and aortic stenosis. He has contributed to several significant publications in prestigious medical journals. He has also served as a Principal Investigator in multiple clinical trials, with particular focus on interventions related to Aortic Valve Replacement and MitraClip therapy. Among his awards are CMS Meaningful Use Stage 1 Certification from EpicCare Ambulatory EMR, and Fellow (FACC) from the American College of Cardiology.

Education & Training

Cleveland Clinic FoundationFellowship, Cardiovascular Disease, 1995 - 1998
Baylor College of MedicineResidency, Internal Medicine, 1991 - 1995
N.H.L Municipal Medical CollegeClass of 1990

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Certifications & Licensure

OH State Medical License 1996 - 2028
MI State Medical License 1995 - 1996
American Board of Internal Medicine Cardiovascular Disease
American Board of Internal Medicine Interventional Cardiology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2011, 2013-2014, 2016-2017
CMS Meaningful Use Stage 2 Certification Beacon Oncology 2014 Certified Module, Epic Systems Corporation, 2011, 2013-2014, 2016-2017
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2011, 2013-2014, 2016-2017

Clinical Trials

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CAS
UNKNOWN
NA
Transcatheter Aortic Valve Replacement System Pivotal Trial
UNKNOWN
NA
ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement Start of enrollment: 2019 Jun 10
ACTIVE_NOT_RECRUITING
NA
Roles: Principal Investigator, Contact

Publications & Presentations

PubMed

The Impact of Anemia on Clinical Outcomes of Patients Above 80 Years Old Following Transcatheter Aortic Valve Replacement.
Besir Besir, Carl Ammoury, Alexander Egoavil, Sada Babazade, Wajeh Abuirmaileh
Structural Heart. 2026-09-01
Long-Term Survival After Transcatheter Aortic Valve Replacement Relative to an Age- and Comorbidity-Matched Population.
Akiva Rosenzveig, Faysal Massad, Osamah Badwan, Ankit Agrawal, Samuel Reiss
JACC. Advances. 2026-08-11
Pacemaker Implantation in Patients With Pre-Existing Bundle Branch Block Undergoing Balloon-Expandable Transcatheter Aortic Valve Replacement.
Judah Rajendran, Shivabalan Kathavarayan Ramu, Carl Ammoury, Besir Besir, Akhilesh Khuttan
Structural Heart. 2026-08-01

Journal Articles

One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart Valve
Brian Whisenant, Samir R Kapadia, Mackram F Eleid, James M Mccabe, Amar Krishnaswamy, Richard W Smalling, Charanjit S Rihal, Raj R Makkar, JAMA Cardiology
Incidence of Stress Cardiomyopathy During the Coronavirus Disease 2019 Pandemic
Hanad Bashir, Khaled M Sleik, Mina K Chung, Umesh N Khot, Samir R Kapadia, JAMA Network Open
Operational Efficiency and Effective Management in the Catheterization Laboratory
Samir Kapadia, MD, ScienceDirect

Abstracts/Posters

[Board 064] Three-Year Outcomes of Transcatheter Aortic Valve Replacement With SAPIEN-3
Samir Kapadia, 2019 ACC Scientific Session & Expo, New Orleans, New Orleans, 3/17/2019

Lectures

LAA Occlusion Plus: MitraClip, TAVR, PCI, and More
CRF Transcatheter Valve Therapy (TVT) - Structural Heart Disease Summit - Chicago, IL - 6/13/2019
Incidence, Trends, Risk Factors, and Comparison With Surgery for Early Stroke After TAVR: Reports From PARTNER and the TVT Registry (in High- and Intermediate-Risk Pat...
CRF Transcatheter Valve Therapy (TVT) - Structural Heart Disease Summit - Chicago, IL - 6/13/2019
Navigate Transcatheter Tricuspid Valve Replacement… Early Findings – Technology and Clinical Updates
CRF Transcatheter Valve Therapy (TVT) - Structural Heart Disease Summit - Chicago, IL - 6/14/2019

Authored Content

One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart ValveJuly 2020
One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart ValveJuly 2020
Incidence of Stress Cardiomyopathy During the Coronavirus Disease 2019 PandemicJuly 2020

Press Mentions

Valve Imaging Summit Offers a Practical, Case-Based Take on the Latest in Valvular Heart DiseaseNovember 14th, 2025
Cleveland Clinic Establishes Cardiovascular Genomics Initiative to Advance Precision Heart CareOctober 29th, 2025
Cleveland Clinic Collaborates with DASI Simulations to Create AI-Powered Technology for Structural Heart CareOctober 16th, 2025