SamuelHaroldSigalMD

Gastroenterology • Bronx, NY

Hepatology & Liver Transplantation

Associate Professor, Medicine, New York University School of Medicine

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Office
111 E 210th St
Bronx, NY 10467
Phone+1 888-795-4837

Fax+1 917-398-8466
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Education & Training

Montefiore Medical Center/Albert Einstein College of Medicine (Moses and Weiler Campuses)Fellowship, Gastroenterology, 1990 - 1993
Icahn School of Medicine at Mount Sinai/Morningside/WestResidency, Internal Medicine, 1987 - 1990
University of Pennsylvania Health SystemResidency, Pathology-Anatomic and Clinical, 1983 - 1987
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1983

Certifications & Licensure

NY State Medical License 1989 - 2024
PA State Medical License 1985 - 1992

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Super Doctor SuperDoctors.com

Clinical Trials

Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleeding Start of enrollment: 2006 May 01
Completed
Phase 3
Rifaximin Versus Lactulose in Renal Failure Start of enrollment: 2008 Jun 01
Withdrawn
Phase 4
Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP) Start of enrollment: 2005 May 01
Unknown status
Phase 4
Hyponatremia Registry for Patients With Euvolemic and Hypervolemic Hyponatremia Start of enrollment: 2010 Sep 01
Completed
The Effect of a Large-volume Paracentesis on Fatigue, Sleep, and Quality of Life in Cirrhosis Start of enrollment: 2012 Jul 01
Withdrawn
The Role of Bacterial Overgrowth and Delayed Intestinal Transit in Hepatic Encephalopathy. Start of enrollment: 2012 Sep 01
Terminated
Not Applicable
Factors Associated With End Stage Liver Disease Start of enrollment: 2012 Jul 01
Terminated
Effect of Music on Attention and Prospective Memory in Hepatic Encephalopathy Start of enrollment: 2012 Dec 01
Withdrawn
Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and Hyponatremia Start of enrollment: 2012 Mar 01
Terminated
Phase 4
The Use of Transient Elastography to Predict Clinical Decompensation in Patients With Early Cirrhosis Start of enrollment: 2014 Oct 01
Withdrawn
A Study of Tirzepatide (LY3298176) in Participants With Nonalcoholic Steatohepatitis (NASH) Start of enrollment: 2019 Nov 19
Completed
Phase 2
Misoprostol for Bloating and Distension Start of enrollment: 2023 Aug 01
Withdrawn
Early Phase 1
Roles: Contact, Principal Investigator
Fresh Frozen Plasma as a Substitute for Albumin in Patients Receiving a Large Volume Paracentesis Start of enrollment: 2019 Nov 11
Withdrawn
Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Eliminating hepatitis B vaccination disparities for West African immigrants.
Jessie A Birnbaum, Daniel Guttman, Mugdha Parulekar, Fatima Omarufilo, Emmanuel U Emeasoba, Julie Nguyen, Oluwadara Tokunboh, Jared Coe, Matthew J Akiyama, Samuel H Sigal> ;Vaccine. 2023 Oct 6
1 citations
Editorial: The US burden of HRS-AKI-Putting numbers to the problem.
Shalom Z Frager, Samuel H Sigal> ;Alimentary Pharmacology & Therapeutics. 2023 Jul 1
Reply.
Samuel H Sigal, S Chris Pappas, Khurram Jamil> ;Clinical Gastroenterology and Hepatology. 2023 Nov 1
1 citations
Terlipressin Treatment Is Associated With Reversal of Hepatorenal Syndrome in Patients With Alcoholic Hepatitis.
Samuel H Sigal, Arun J Sanyal, R Todd Frederick, Ethan M Weinberg, S Chris Pappas, Khurram Jamil> ;Clinical Gastroenterology and Hepatology. 2023 Dec 1
4 citations
Breaking down barriers for hepatitis B screening in the Bronx West African community through education in collaboration with faith-based organizations: A cohort study.
Emmanuel U Emeasoba, Fatima Omarufilo, John Nnaemeka Bosah, Samuel H Sigal> ;Lancet Regional Health. Americas. 2022 Mar 1
1 citations
Admission Serum Bicarbonate Predicts Adverse Clinical Outcomes in Hospitalized Cirrhotic Patients.
Michael Schopis, Anand Kumar, Michael K. Parides, Adam Tepler, Samuel H. Sigal> ;Canadian Journal of Gastroenterology & Hepatology. 2021 May 17
15 citations
Eight Weeks of Treatment With Glecaprevir/Pibrentasvir Is Safe and Efficacious in an Integrated Analysis of Treatment-Naïve Patients With Hepatitis C Virus Infection.
Eli Zuckerman, Julio A. Gutierrez, Douglas E. Dylla, Victor de Ledinghen, Andrew J. Muir, Michael Gschwantler, Massimo Puoti, Florin Caruntu, Jihad Slim, Frederik Neve...> ;Clinical Gastroenterology and Hepatology. 2020 Oct 1
10 citations
Clinical Implications of Thrombocytopenia for the Cirrhotic Patient.
Samuel H. Sigal, Zachary Sherman, Arun Jesudian> ;Hepatic Medicine. 2020 Apr 14
13 citations
Management Strategies and Outcomes for Hyponatremia in Cirrhosis in the Hyponatremia Registry
Samuel H. Sigal, Alpesh Amin, Joseph Chiodo, Arun J. Sanyal> ;Canadian Journal of Gastroenterology & Hepatology. 2018 Sep 27
6 citations
Transjugular intrahepatic portosystemic shunt creation for cirrhotic portal hypertension is well tolerated among patients with portal vein thrombosis.
Jonathan Merola, Brett E. Fortune, Yanhong Deng, Maria M. Ciarleglio, Smbat Amirbekian, Noami Chaudhary, Alampady Krishna Prasad Shanbhogue, R. Ayyagari, Manuel I. Rod...> ;European Journal of Gastroenterology & Hepatology. 2018 Jan 1
14 citations
Colchicine-Induced Hepatotoxicity.
Collette E. Abbott, Ruliang Xu, Samuel H. Sigal> ;ACG Case Reports Journal. 2017 Nov 22
10 citations
Frequency and pathological characteristics of drug-induced liver injury in a tertiary medical center.
Mark Ettel, Gabriel Acosta Gonzalez, Shweta Gera, Ogechukwu Eze, Samuel H. Sigal, James S. Park, Ruliang Xu> ;Human Pathology. 2017 Oct 1
52 citations
Child-Turcotte-Pugh Class is Best at Stratifying Risk in Variceal Hemorrhage: Analysis of a US Multicenter Prospective Study.
Brett E. Fortune, Guadalupe Garcia-Tsao, Maria M. Ciarleglio, Yanhong Deng, Michael B. Fallon, Samuel H. Sigal, Naga Chalasani, Joseph K. Lim, Adrian Reuben, Hugo E. V...> ;Journal of Clinical Gastroenterology. 2017 May 1
176 citations
Terlipressin Plus Albumin Is More Effective Than Albumin Alone in Improving Renal Function in Patients With Cirrhosis and Hepatorenal Syndrome Type 1
Thomas D. Boyer, Arun J. Sanyal, Florence Wong, R. Todd Frederick, John R. Lake, Jacqueline G. O'Leary, Daniel Ganger, Khurram Jamil, Stephen Chris Pappas, Samuel H. S...> ;Gastroenterology. 2016 Jun 1
3 citations
Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome
Farhad Sahebjam, Cristina H. Hajdu, Esther Nortey, Samuel H. Sigal> ;World Journal of Hepatology. 2016 May 18
107 citations
The pathophysiology of thrombocytopenia in chronic liver disease.
Oscar J.L. Mitchell, David M. Feldman, Marla Diakow, Samuel H. Sigal> ;Hepatic Medicine. 2016 Apr 15
25 citations
Impact of depressive symptoms and hepatic encephalopathy on health-related quality of life in cirrhotic hepatitis C patients
Katherine C. Barboza, Lilian Salinas, Farhad Sahebjam, Arun Jesudian, Samuel H. Sigal> ;Metabolic Brain Disease. 2016 Mar 31
Periodontal Management of a Patient Undergoing Liver Transplantation.
Emanuele Clozza, Stuart L. Segelnick, Samuel H. Sigal, Deborah N Rovner, Mea A. Weinberg> ;The International Journal of Periodontics & Restorative Dentistry. 2016 Mar 1
2 citations
The Effect of Colonoscopy Reimbursement Reductions on Gastroenterologist Practice Behavior.
Matthew B. McNeill, Shannon Chang, Farhad Sahebjam, Adam J. Goodman, Seth A. Gross, Samuel H. Sigal> ;Digestive Diseases and Sciences. 2016 Jan 19
32 citations
Natalizumab-induced hepatic injury: A case report and review of literature
A. Antezana, Samuel H. Sigal, Joseph Herbert, Ilya Kister> ;Multiple Sclerosis and Related Disorders. 2015 Nov 1
4 citations
Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
Edoardo G. Giannini, Nezam H. Afdhal, Samuel H. Sigal, Andrew J. Muir, K. Rajender Reddy, Shanthi Vijayaraghavan, Magdy Elkashab, Manuel Romero-Gómez, Geoffrey Dusheik...> ;Journal of Gastroenterology and Hepatology. 2015 Aug 1
119 citations
Current treatment practice and outcomes. Report of the hyponatremia registry
Arthur Greenberg, Joseph G. Verbalis, Alpesh Amin, Volker Burst, Joseph Chiodo, Jun R. Chiong, Joseph F. Dasta, Keith Friend, Paul J. Hauptman, Alessandro Peri, Samuel...> ;Kidney International. 2015 Jul 1
44 citations
Estimating liver perfusion from free-breathing continuously acquired dynamic gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced acquisition with comp...
Hersh Chandarana, Tobias K. Block, Justin M. Ream, Artem Mikheev, Samuel H. Sigal, Ricardo Otazo, Henry Rusinek> ;Investigative Radiology. 2015 Feb 1
4 citations
Treatment of gastric varices with partial splenic embolization in a patient with portal vein thrombosis and a myeloproliferative disorder.
Robert J. Gianotti, Hearns Charles, Kenneth Hymes, Hersh Chandarana, Samuel H. Sigal> ;World Journal of Gastroenterology. 2014 Oct 21
65 citations
Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin.
Jordan J Feld, Kris V Kowdley, Eoin Coakley, Samuel Sigal, David R Nelson, Darrell Crawford, Ola Weiland, Humberto Aguilar, Junyuan Xiong, Tami Pilot-Matias, Barbara D...> ;The New England Journal of Medicine. 2014 Apr 24
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