SandraLDaboraMD

PubMed

• 10 citations
  Similar trends in serum VEGF-D levels and kidney angiomyolipoma responses with longer duration sirolimus treatment in adults with tuberous sclerosis.
  Izabela A. Malinowska, Nancy Lee, Vidhya Kumar, Elizabeth A. Thiele, David Neal Franz, Stephen Ashwal, Arthur I. Sagalowsky, Francis J. DiMario, Drew Cutler, Darcy A. ...> ;Plos One. 2013 Feb 20
• 142 citations
  Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease
  Sandra L. Dabora, David Neal Franz, Stephen Ashwal, Arthur I. Sagalowsky, Francis J. DiMario, Daniel K. Miles, Drew Cutler, Darcy A. Krueger, Raul N. Uppot, Rahmin A. ...> ;Plos One. 2011 Sep 6
• 34 citations
  Comparison of three rapamycin dosing schedules in A/J Tsc2 +/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneo...
  Chelsey L Woodrum, Alison M Nobil, Sandra L. Dabora> ;Journal of Translational Medicine. 2010 Feb 10
• 189 citations
  Tsc2-Rheb signaling regulates EphA-mediated axon guidance
  Duyu Nie, Alessia Di Nardo, Juliette M. Han, Hasani Baharanyi, Ioannis Kramvis, Thanhthao Huynh, Sandra L. Dabora, Simone Codeluppi, Pier Paolo Pandolfi, Elena B. Pasq...> ;Nature Neuroscience. 2010 Feb 1
• 63 citations
  Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis precli...
  Nancy Lee, Chelsey L Woodrum, Alison M Nobil, Aubrey Rauktys, Michael P Messina, Sandra L. Dabora> ;BMC Pharmacology. 2009 Apr 15
• 34 citations
  Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model.
  Aubrey Rauktys, Nancy Lee, Laifong Lee, Sandra L. Dabora> ;BMC Dermatology. 2008 Jan 28
• 19 citations
  Tuberous sclerosis preclinical studies: timing of treatment, combination of a rapamycin analog (CCI-779) and interferon-gamma, and comparison of rapamycin to CCI-779
  Michael P Messina, Aubrey Rauktys, Laifong Lee, Sandra L. Dabora> ;BMC Pharmacology. 2007 Nov 6
• 140 citations
  Potential Histologic and Molecular Predictors of Response to Temsirolimus in Patients with Advanced Renal Cell Carcinoma
  Daniel Cho, Sabina Signoretti, Sandra L. Dabora, Meredith M. Regan, Apryle Seeley, Mauro Mariotti, Amanda Youmans, Adam Polivy, Lucy Mandato, David F. McDermott, Eric ...> ;Clinical Genitourinary Cancer. 2007 Sep 1
• 302 citations
  PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR
  Hongbing Zhang, Natalia Bajraszewski, Erxi Wu, Hong-Wei Wang, Annie P. Moseman, Sandra L. Dabora, James D. Griffin, David J. Kwiatkowski> ;The Journal of Clinical Investigation. 2007 Mar 1
• 132 citations
  Identification of 54 large deletions/duplications in TSC1 and TSC2 using MLPA, and genotype-phenotype correlations
  Piotr Kozlowski, Penelope S. Roberts, Sandra L. Dabora, David Neal Franz, John J. Bissler, Hope Northrup, Kit Sing Au, Ross Lazarus, Dorota Domańska-Pakieła, Katarzyna...> ;Human Genetics. 2007 Feb 8
• 32 citations
  Combination of a rapamycin analog (CCI-779) and interferon-gamma is more effective than single agents in treating a mouse model of tuberous sclerosis complex.
  Laifong Lee, Paul Sudentas, Sandra L. Dabora> ;Genes, Chromosomes & Cancer. 2006 Oct 1
• 130 citations
  Efficacy of a rapamycin analog (CCI-779) and IFN-? in tuberous sclerosis mouse models
  Laifong Lee, Paul Sudentas, Brian Donohue, Kirsten Asrican, Aelaf Worku, Victoria Walker, Yanping Sun, Karl Schmidt, Mitchell S. Albert, Nisreen El-Hashemite, Alan S. ...> ;Genes, Chromosomes & Cancer. 2005 Mar 1
• 21 citations
  Somatic mosaicism is rare in unaffected parents of patients with sporadic tuberous sclerosis
  Penelope S. Roberts, Sandra L. Dabora, Elizabeth A. Thiele, David Neal Franz, S. Jozwiak, David J. Kwiatkowski> ;Journal of Medical Genetics. 2004 May 1
• 8 citations
  A 34 bp deletion within TSC2 is a rare polymorphism, not a pathogenic mutation.
  Penelope S. Roberts, Vijaya Ramesh, Sandra L. Dabora, David J. Kwiatkowski> ;Annals of Human Genetics. 2003 Nov 1
• 37 citations
  Association between a High-Expressing Interferon-γ Allele and a Lower Frequency of Kidney Angiomyolipomas in TSC2 Patients
  Sandra L. Dabora, Penelope S. Roberts, Andres Nieto, Ronald Perez, Sergiusz Jozwiak, David Neal Franz, John J. Bissler, Elizabeth A. Thiele, Katherine B. Sims, David J...> ;American Journal of Human Genetics. 2002 Oct 1
• 8 citations
  SNP identification, haplotype analysis, and parental origin of mutations in TSC2.
  Penelope S. Roberts, Joon Chung, S. Jozwiak, Sandra L. Dabora, David Neal Franz, Elizabeth A. Thiele, David J. Kwiatkowski> ;Human Genetics. 2002 Jun 7
• 17 citations
  Pulmonary cysts consistent with lymphangioleiomyomatosis are common in women with tuberous sclerosis: genetic and radiographic analysis.
  Francis X. McCormack, Alan S. Brody, Christopher S. Meyer, Jennifer Leonard, Gail Chuck, Sandra L. Dabora, Gopalan Sethuraman, Thomas V. Colby, David J. Kwiatkowski, D...> ;Chest. 2002 Mar 1
• 201 citations
  Mutational and radiographic analysis of pulmonary disease consistent with lymphangioleiomyomatosis and micronodular pneumocyte hyperplasia in women with tuberous scler...
  David Neal Franz, Alan S. Brody, Cristopher A. Meyer, Jennifer Leonard, Gail Chuck, Sandra L. Dabora, Gopalan Sethuraman, Thomas V. Colby, David J. Kwiatkowski, Franci...> ;American Journal of Respiratory and Critical Care Medicine. 2001 Aug 15
• 23 citations
  Denaturing high-performance liquid chromatography (DHPLC) is a highly sensitive, semi-automated method for identifying mutations in the TSC1 gene.
  Penelope S. Roberts, Sergiusz Jozwiak, David J. Kwiatkowski, Sandra L. Dabora> ;Journal of Biochemical and Biophysical Methods. 2001 Jan 30
• 674 citations
  Mutational Analysis in a Cohort of 224 Tuberous Sclerosis Patients Indicates Increased Severity of TSC2, Compared with TSC1, Disease in Multiple Organs
  Sandra L. Dabora, Sergiusz Jozwiak, David Neal Franz, Penelope S. Roberts, Andres Nieto, Joon Chung, Yew-Sing Choy, Mary Pat Reeve, Elizabeth A. Thiele, John C. Egelho...> ;American Journal of Human Genetics. 2001 Jan 1
• 12 citations
  Characterisation of six large deletions in TSC2 identified using long range PCR suggests diverse mechanisms including Alu mediated recombination
  Sandra L. Dabora, Andres Nieto, David Neal Franz, S. Jozwiak, A. M. W. Van Den Ouweland, David J. Kwiatkowski> ;Journal of Medical Genetics. 2000 Nov 1
• 88 citations
  Superiority of denaturing high performance liquid chromatography over single-stranded conformation and conformation-sensitive gel electrophoresis for mutation detectio...
  Y. S. Choy, Sandra L. Dabora, F. Hall, Vijaya Ramesh, Yo Niida, David Neal Franz, Jolanta Kasprzyk-Obara, Mary Pat Reeve, David J. Kwiatkowski> ;Annals of Human Genetics. 1999 Sep 1
• 16 citations
  Comprehensive mutation analysis of TSC1 using two-dimensional DNA electrophoresis with DGGE.
  Sandra L. Dabora, I. Sigalas, F. Hall, Charis Eng, J. Vijg, David J. Kwiatkowski> ;Annals of Human Genetics. 1998 Nov 1
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