SantoshaAdipudiVardhanaMD

PubMed

• Somatic mutations in FAS pathway increase hemophagocytic lymphohistiocytosis risk in T- and/or NK-cell lymphoma patients.
  Rohan Sardana, David Nemirovsky, Denise Frosina, Achim Jungbluth, Maria E Arcila, Andriy Derkach, Ying Liu, William T Johnson, Santosha A Vardhana, Steven M Horwitz, A...> ;Blood Advances. 2024 Apr 9
• Gemcitabine plus pembrolizumab after checkpoint blockade failure as a strategy in multiply relapsed Hodgkin lymphoma.
  Robert Stuver, Ariela Noy, Santosha A Vardhana, Andrew D Zelenetz, Alison J Moskowitz> ;British Journal of Haematology. 2024 Feb 1
• Disease response upon cessation of methotrexate in a patient with Hodgkin lymphoma treated with pembrolizumab.
  Robert Stuver, Santosha A Vardhana, Akshay Bedmutha, Karmela Kim Chan, Rosna Mirtcheva-Trocheva, Anton Nosov, Heiko Schöder, Alison Moskowitz> ;Leukemia & Lymphoma. 2023 Dec 1
• 1 citations
  Unique Genomic Alterations and Microbial Profiles Identified in Patients With Gastric Cancer of African, European, and Asian Ancestry: A Novel Path for Precision Oncol...
  Miseker Abate, Henry Walch, Kanika Arora, Chad M Vanderbilt, Teng Fei, Harrison Drebin, Shoji Shimada, Anna Maio, Yelena Kemel, Zsofia K Stadler, Joseph Schmeltz, Smit...> ;Annals of Surgery. 2023 Oct 1
• 6 citations
  Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells.
  Caleb A Lareau, Sonia M Dubois, Frank A Buquicchio, Yu-Hsin Hsieh, Kopal Garg, Pauline Kautz, Lena Nitsch, Samantha D Praktiknjo, Patrick Maschmeyer, Jeffrey M Verboon...> ;Nature Genetics. 2023 Jul 1
• 1 citations
  Retrospective characterization of nodal marginal zone lymphoma.
  Robert Stuver, Esther Drill, David Qualls, Michelle Okwali, Connie Lee Batlevi, Philip C Caron, Ahmet Dogan, Zachary D Epstein-Peterson, Lorenzo Falchi, Paul A Hamlin,...> ;Blood Advances. 2023 Sep 12
• High-throughput interrogation of immune responses using the Human Immune Profiling Pipeline.
  Guanning Wang, Olga Lyudovyk, Justin Y Kim, Ya-Hui Lin, Yuval Elhanati, Divij Mathew, E John Wherry, Ramin S Herati, Allison R Greenplate, Benjamin Greenbaum, Santosha...> ;STAR Protocols. 2023 May 8
• 3 citations
  TP53 mutations identify high-risk events for peripheral T-cell lymphoma treated with CHOP-based chemotherapy.
  William T Johnson, Nivetha Ganesan, Zachary D Epstein-Peterson, Alison J Moskowitz, Robert N Stuver, Catherine R Maccaro, Natasha Galasso, Tiffany Chang, Niloufer Khan...> ;Blood Advances. 2023 Sep 12
• 4 citations
  Risk of Lymph Node Metastasis in T1b Gastric Cancer: An International Comprehensive Analysis from the Global Gastric Group (G3) Alliance.
  Elvira L Vos, Masaya Nakauchi, Mithat Gönen, Jason A Castellanos, Alberto Biondi, Daniel G Coit, Johan L Dikken, Domenico D'ugo, Henk Hartgrink, Ping Li, Makoto Nishim...> ;Annals of Surgery. 2023 Feb 1
• 1 citations
  Not so neutral lipids: Metabolic regulation of the pre-metastatic niche.
  Joshua D Schoenfeld, Santosha A Vardhana> ;Cell Metabolism. 2022 Dec 6
• 33 citations
  Bispecific antibodies for the treatment of B-cell lymphoma: promises, unknowns, and opportunities.
  Lorenzo Falchi, Santosha A Vardhana, Gilles A Salles> ;Blood. 2023 Feb 2
• 34 citations
  SARS-CoV-2 in immunocompromised individuals.
  Susan DeWolf, Justin C Laracy, Miguel-Angel Perales, Mini Kamboj, Marcel R M van den Brink, Santosha Vardhana> ;Immunity. 2022 Oct 11
• Discordant SARS-CoV-2 spike protein receptor binding domain IgG and neutralization after B-cell depletion.
  Ariela Noy, Santosha A Vardhana> ;Haematologica. 2022 Dec 1
• 12 citations
  A Novel Microbiome Signature in Gastric Cancer: A Two Independent Cohort Retrospective Analysis.
  Miseker Abate, Elvira Vos, Mithat Gonen, Yelena Y Janjigian, Mark Schattner, Monika Laszkowska, Laura Tang, Steven B Maron, Daniel G Coit, Santosh Vardhana, Chad Vande...> ;Annals of Surgery. 2022 Oct 1
• 17 citations
  Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses.
  Olga Lyudovyk, Justin Y Kim, David Qualls, Madeline A Hwee, Ya-Hui Lin, Sawsan R Boutemine, Yuval Elhanati, Alexander Solovyov, Melanie Douglas, Eunise Chen, N Esther ...> ;Cancer Cell. 2022 Jul 11
• 61 citations
  Activity of AZD7442 (tixagevimab-cilgavimab) against Omicron SARS-CoV-2 in patients with hematologic malignancies.
  Robert Stuver, Gunjan L Shah, Neha S Korde, Lindsey E Roeker, Anthony R Mato, Connie L Batlevi, David J Chung, Sital Doddi, Lorenzo Falchi, Boglarka Gyurkocza, Audrey ...> ;Cancer Cell. 2022 Jun 13
• 82 citations
  Understanding T cell responses to COVID-19 is essential for informing public health strategies.
  Santosha Vardhana, Lance Baldo, William G Morice 2nd, E John Wherry> ;Science Immunology. 2022 May 20
• 3 citations
  Magnesium for T cells: strong to the finish!
  Santosha Vardhana, Michael L Dustin> ;Trends in Immunology. 2022 Apr 1
• Vive la Résistance: T-cell Immunity in the Protection against SARS-CoV-2 Infection.
  Lisa H F McGary, Santosha A Vardhana> ;Cancer Discovery. 2022 Apr 1
• Challenges and opportunities in 2021.
  Leila Akkari, Stacey D Finley, Ping-Chih Ho, Misty Jenkins, Barbara B Maier, Nicholas McGranahan, Miriam Mutebi, Rushika M Perera, Carla Daniela Robles-Espinoza, Santo...> ;Nature Cancer. 2021 Dec 1
• 55 citations
  Prolonged SARS-CoV-2 infection in patients with lymphoid malignancies.
  Christina Y. Lee, Monika K. Shah, David Hoyos, Alexander Solovyov, Melanie Douglas, Ying Taur, Peter Maslak, N. Esther Babady, Benjamin Greenbaum, Mini Kamboj, Santosh...> ;Cancer Discovery. 2021 Nov 9
• 54 citations
  Phase II biomarker-driven study of ruxolitinib demonstrates effectiveness of JAK/STAT targeting in T-cell lymphomas.
  Alison J. Moskowitz, Paola Ghione, Eric D. Jacobsen, Jia Ruan, Jonathan H. Schatz, Sarah J. Noor, Patricia L. Myskowski, Santosha A. Vardhana, Nivetha Ganesan, Helen H...> ;Blood. 2021 Oct 19
• 19 citations
  Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.
  Melissa D. Docampo, Marina Burgos da Silva, Amina Lazrak, Katherine B Nichols, Sophia R. Lieberman, Ann E. Slingerland, Gabe K Armijo, Yusuke Shono, Chi L. Nguyen, Seb...> ;Blood. 2021 Oct 15
• 27 citations
  Metabolic regulation of the cancer-immunity cycle.
  Luis F. Somarribas Patterson, Santosha Vardhana> ;Trends in Immunology. 2021 Nov 1
• 39 citations
  Disease- and Therapy-Specific Impact on Humoral Immune Responses to COVID-19 Vaccination in Hematologic Malignancies.
  David J. Chung, Gunjan L. Shah, Sean M. Devlin, Lakshmi V. Ramanathan, Sital Doddi, Melissa S. Pessin, Elizabeth Hoover, Leeann Marcello, Jennifer C. Young, Sawsan R. ...> ;Blood Cancer Discovery. 2021 Sep 13
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Abstracts/Posters

• High Complete Response Rate Observed with Second-Line Chemo-Immunotherapy with Pembrolizumab and GVD (Gemcitabine, Vinorelbine, and Liposomal Doxorubicin) in Relapsed ...
  Santosha Vardhana, 61st Annual American Society of Hematology Meeting, 61st Annual American Society of Hematology Meeting - Orlando, FL, 12/8/2019
• Retrospective Analysis of Gemcitabine and Oxaliplatin (GemOx)-Based Treatment in Patients with Relapsed/Refractory Aggressive B-Cell Non-Hodgkin Lymphoma
  Santosha Vardhana, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019