Sara Isabel Pai MD PhD
Head & Neck Oncologic Surgery
Massachusetts General Hospital, Harvard Medical School/ Director, Translational Head and Neck Cancer Research
Join to View Full Profile
35 Park StSmilow Cancer Hospital at Yale New HavenNew Haven, CT 06510
Dr. Pai is on Doximity
As a Doximity member, you’ll join more than three million U.S. healthcare professionals—including 85+% of physicians, and 2/3 of all NPs and PAs—in a private, secure network.
- Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
- Connect with colleagues in the same hospital or clinic.
- Read the latest clinical news, personalized to your specialty.
Education & Training
Johns Hopkins UniversityResidency, Otolaryngology - Head and Neck Surgery, 2003 - 2007- Johns Hopkins UniversityInternship, Surgery, 2002 - 2003
- Johns Hopkins UniversityInternship, Otolaryngology - Head and Neck Surgery, 2002 - 2003
- Johns Hopkins University School of MedicineClass of 2002
Certifications & Licensure
CT State Medical License 2023 - 2027
MD State Medical License 2007 - 2027
MA State Medical License 2014 - 2026
ME State Medical License 2020 - 2021
American Board of Otolaryngology - Head and Neck Surgery Otolaryngology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2014
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
- Fellow (FACS) American College of Surgeons
Clinical Trials
- Merck IIT: RRP Pembro and Lenvatinib Start of enrollment: 2025 Jul 18
Publications & Presentations
PubMed
- The Patient Perspective of Living With Recurrent Respiratory Papillomatosis.Sara I Pai, Walter Ochieng, Nancy Hedlund, Amanda Martino, Neha Chohan
The Laryngoscope. 2026-07-01 - In Response to A Clinical Consensus Statement on Pulmonary Recurrent Respiratory Papillomatosis.Nikita Kohli, Sara I Pai, Julia Buckingham, Yvonne Carter, Nabil F Saba
The Laryngoscope. 2026-04-01 - Biomarkers Associated With Extranodal Extension (ENE) in Oropharyngeal Squamous Cell Carcinoma (OPSCC): A Systematic Review.Lauren C Williams, Naishaliz Lorenzo, Alexander Ladenheim, Saral Mehra, Benjamin L Judson
Head & Neck. 2026-03-26
Lectures
- A phase II study of pembrolizumab for HPV-associated papilloma patients with laryngeal, tracheal, and/or pulmonary involvement.2019 ASCO Annual Meeting - 6/1/2019
- ICR gene signature to identify differential immune landscapes in anatomic subsites of head and neck squamous cell carcinomas and implications in personalized medicine.2018 ASCO Annual Meeting - Chicago, Illinois - 06/2/2018
Press Mentions
Yale Surgeon-Scientist Secures FDA Orphan Drug Designation for Pembrolizumab in Rare Respiratory DiseaseJanuary 7th, 2025- Research Spotlight: The Effects of Periodontitis on Cancer Outcomes in the Era of ImmunotherapyJune 29th, 2023
Grant Support
- Cue-101 and TCR-T cell Combinatorial Strategy for HPV+ Head and Neck CancersYALE UNIVERSITY2024–2029
- Early detection and risk of head and neck cancer through immune based spatial omicsYALE UNIVERSITY2024–2028
- FAST-FNA immune cell profiling in HNSCCMASSACHUSETTS GENERAL HOSPITAL2021–2025
- Strategies to Overcome Immune Resistance in Head and Neck CancersYALE UNIVERSITY2019–2025
- HPV Vaccine Therapy And Correlates Of Response In Head And Neck Squamous CellNational Institute Of Dental &Craniofacial Research2007–2011
Professional Memberships
- Fellow
- Member
- Member
- Member
Other Languages
- Spanish, Korean
Viewing the full profile is available to verified healthcare professionals only.
Find your profile and take control of your online presence:
