SaraSeligMD

PubMed

• 2 citations
  RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function.
  Nadra Samra, Shir Toubiana, Hilde Yttervik, Aya Tzur-Gilat, Ilham Morani, Chen Itzkovich, Liran Giladi, Kamal Abu Jabal, John Z. Cao, Lucy A. Godley, Adi Mory, Hagit B...> ;Journal of Human Genetics. 2021 May 13
• 2 citations
  Epigenetic Characteristics of Human Subtelomeres Vary in Cells Utilizing the Alternative Lengthening of Telomeres (ALT) Pathway.
  Shir Toubiana, Aya Tzur-Gilat, Sara Selig> ;Life. 2021 Mar 26
• 12 citations
  The Latest on Uveal Melanoma Research and Clinical Trials: Updates from the Cure Ocular Melanoma (CURE OM) Science Meeting (2019).
  Vivian Chua, Jane Mattei, Anna Han, Lauren Johnston, Kyleigh LiPira, Sara Selig, Richard D. Carvajal, Andrew E. Aplin, Sapna Pradyuman Patel> ;Clinical Cancer Research. 2021 Jan 1
• 4 citations
  Regulation of telomeric function by DNA methylation differs between humans and mice.
  Shir Toubiana, Gal Larom, Riham Smoom, Robert Duszynski, Lucy A. Godley, Claire Francastel, Guillaume Velasco, Sara Selig> ;Human Molecular Genetics. 2020 Nov 25
• 36 citations
  Impact of a Fruit and Vegetable Prescription Program on Health Outcomes and Behaviors in Young Navajo Children.
  Leandra J Jones, Joan Vanwassenhove-Paetzold, Kymie Thomas, Carolyn Bancroft, E Quinn Ziatyk, Lydia Soo-Hyun Kim, Ariel Shirley, Abigail C. Warren, Lindsey Hamilton, C...> ;Current Developments in Nutrition. 2020 Aug 1
• 9 citations
  Implementation of the Navajo fruit and vegetable prescription programme to improve access to healthy foods in a rural food desert.
  Michael A Sundberg, Abigail C. Warren, Joan Vanwassenhove-Paetzold, Carmen George, Danya S. Carroll, Leandra Jewel Becenti, Akeemi Martinez, Burrell Jones, Karen Bachm...> ;Public Health Nutrition. 2020 May 13
• 16 citations
  Human subtelomeric DNA methylation: regulation and roles in telomere function.
  Shir Toubiana, Sara Selig> ;Current Opinion in Genetics & Development. 2020 Feb 1
• 17 citations
  Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction.
  Shir Toubiana, Miriam Gagliardi, Mariarosaria Papa, Roberta Manco, Maty Tzukerman, Maria R. Matarazzo, Sara Selig> ;Elife. 2019 Nov 18
• 23 citations
  Subtelomeric methylation distinguishes between subtypes of Immunodeficiency, Centromeric instability and Facial anomalies syndrome.
  Shir Toubiana, Guillaume Velasco, Adi Chityat, Angela M. Kaindl, Noam Hershtig, Aya Tzur-Gilat, Claire Francastel, Sara Selig> ;Human Molecular Genetics. 2018 Oct 15
• 42 citations
  DNA:RNA hybrids at telomeres – when it is better to be out of the (R) loop
  Shir Toubiana, Sara Selig> ;The FEBS Journal. 2018 Jul 1
• 17 citations
  No Equity, No Triple Aim: Strategic Proposals to Advance Health Equity in a Volatile Policy Environment
  Geoffrey Wilkinson, Alan Sager, Sara Selig, Richard C. Antonelli, Samantha Morton, Gail R. Hirsch, Celeste Reid Lee, Abigail Ortiz, Durrell J. Fox, Monica Valdes Lupi,...> ;American Journal of Public Health. 2017 Dec 13
• 10 citations
  Non-random length distribution of individual telomeres in immunodeficiency, centromeric instability and facial anomalies syndrome, type I.
  Shira Sagie, Omer Edni, Joseph Weinberg, Shir Toubiana, Tal Kozlovski, Tzviel Frostig, Nirit Katzin, Irit Bar-Am, Sara Selig> ;Human Molecular Genetics. 2017 Nov 1
• 73 citations
  Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids.
  Shira Sagie, Shir Toubiana, Stella R. Hartono, Hagar Katzir, Aya Tzur-Gilat, Shany Havazelet, Claire Francastel, Guillaume Velasco, Frédéric Chédin, Sara Selig> ;Nature Communications. 2017 Jan 24
• 84 citations
  Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects.
  Amos J. Simon, Atar Lev, Yong Zhang, Batia Weiss, Anna Rylova, Eran Eyal, Nitzan Kol, Ortal Barel, Keren Cesarkas, Michalle Soudack, Noa Greenberg-Kushnir, Michele Rho...> ;The Journal of Experimental Medicine. 2016 Jul 25
• 68 citations
  Biology of advanced uveal melanoma and next steps for clinical therapeutics
  Jason J. Luke, Pierre L. Triozzi, Kyle C. McKenna, Erwin G. Van Meir, Jeffrey E. Gershenwald, Boris C. Bastian, J. Silvio Gutkind, Anne M. Bowcock, Howard Streicher, P...> ;Pigment Cell & Melanoma Research. 2015 Mar 1
• 28 citations
  Induced pluripotent stem cells as a model for telomeric abnormalities in ICF type I syndrome
  Shira Sagie, Erika Ellran, Hagar Katzir, Rony Shaked, Shiran Yehezkel, Ilana Laevsky, Alaa Ghanayim, Dan Geiger, Maty Tzukerman, Sara Selig> ;Human Molecular Genetics. 2014 Jul 15
• 31 citations
  Characterization and rescue of telomeric abnormalities in ICF syndrome type I fibroblasts.
  Shiran Yehezkel, Rony Shaked, Shira Sagie, Ron Berkovitz, Hofit Shachar-Bener, Yardena Segev, Sara Selig> ;Frontiers in Oncology. 2013 Feb 28
• 2 citations
  Digital image analysis of cells stained with the senescence-associated β-galactosidase assay.
  Liran I. Shlush, Sara Selig> ;Methods in Molecular Biology. 2013 Jan 1
• 29 citations
  Quantitative digital in situ senescence-associated β-galactosidase assay
  Liran I. Shlush, Shalev Itzkovitz, Ariel Cohen, Aviad Rutenberg, Ron Berkovitz, Shiran Yehezkel, Hofit Shahar, Sara Selig, Karl Skorecki> ;BMC Cell Biology. 2011 Apr 15
• 30 citations
  Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress--implications for tissue and organismal aging.
  Liran I. Shlush, Karl Skorecki, Shalev Itzkovitz, Shiran Yehezkel, Yardena Segev, Hofit Shachar, Ron Berkovitz, Yochai Adir, Irma Vulto, Peter M. Lansdorp, Sara Selig> ;Mechanisms of Ageing and Development. 2011 Mar 1
• 63 citations
  Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives.
  Shiran Yehezkel, Annie Rebibo-Sabbah, Yardena Segev, Maty Tzukerman, Rony Shaked, Irit Huber, Lior Gepstein, Karl Skorecki, Sara Selig> ;Epigenetics. 2011 Jan 1
• 87 citations
  Altered Chromosomal Positioning, Compaction, and Gene Expression with a Lamin A/C Gene Mutation
  Stephanie K. Mewborn, Megan J. Puckelwartz, Fida Abuisneineh, John Fahrenbach, Yuan Zhang, Heather MacLeod, Lisa Dellefave, Peter Pytel, Sara Selig, Christine M. Labno...> ;Plos One. 2010 Dec 14
• 36 citations
  The Gag cleavage product, p12, is a functional constituent of the murine leukemia virus pre-integration complex.
  Adi Prizan-Ravid, Efrat Elis, Nihay Laham-Karam, Sara Selig, Marcelo Ehrlich, Eran Bacharach> ;Plos Pathogens. 2010 Nov 11
• 70 citations
  Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene.
  Shay Tzur, Saharon Rosset, Revital Shemer, Guennady Yudkovsky, Sara Selig, Ayele Tarekegn, Endashaw Bekele, Neil Bradman, Walter G Wasser, Doron M Behar, Karl Skorecki> ;Human Genetics. 2010 Sep 1
• 67 citations
  African ancestry allelic variation at the MYH9 gene contributes to increased susceptibility to non-diabetic end-stage kidney disease in Hispanic Americans
  Doron M. Behar, Saharon Rosset, Shay Tzur, Sara Selig, Guennady Yudkovsky, Sivan Bercovici, Jeffrey B. Kopp, Cheryl A. Winkler, George W. Nelson, Walter G. Wasser, Kar...> ;Human Molecular Genetics. 2010 May 1
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