Sarah A. Holstein MD PhD, FACP

PubMed

• Impact of fixed phosphorus position on activity of triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors.
  Md Ayub Ali, Mona A Maalouf, Dan Feng, Mamunur Rashid, Nathaniel R Gehrke
  Bioorganic & Medicinal Chemistry. 2025-05-01
• A phase 2 randomized study of modakafusp alfa as a single agent in patients with relapsed/refractory multiple myeloma.
  Sarah A Holstein, Shebli Atrash, Hira Mian, Meletios Athanasios Dimopoulos, Fredrik Schjesvold
  Blood. 2025-04-25
• 1 citations
  Structure-activity relationship of isoprenoid triazole bisphosphonate-based geranylgeranyl diphosphate synthase inhibitors: Effects on pharmacokinetics, biodistributio...
  Staci L Haney, Yashpal S Chhonker, Mamunur Rashid, Daryl J Murry, Sarah A Holstein
  Drug Metabolism and Disposition. 2025-03-01

Abstracts/Posters

• Geranylgeranyl Diphosphate Synthase Inhibitor and Proteasome Inhibitor Combination Therapy in Multiple Myeloma
  Sarah A. Holstein, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• In Vitro and in Vivo Activity of Melflufen in Amyloidosis
  Sarah A. Holstein, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• The Effect of Age and CD34+ Stem Cell Dose on Autologous Hematopoietic Stem Cell Transplantation Outcomes in Multiple Myeloma _ Single Institution Experience
  Sarah A. Holstein, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Effect of Using Multiagent Versus Single Agent Chemotherapy on Overall Survival (OS) of Older Adults with Acute Myeloid Leukemia (AML)
  Sarah A. Holstein, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Integrating Geriatric Assessment and Genetic Profiling to Personalize Therapy Selection in Older Adults with Acute Myeloid Leukemia (AML)
  Sarah A. Holstein, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures

• Results of a Phase I Study of Pnk-007, Allogeneic, Off the Shelf NK Cell, Post Autologous Transplant in Multiple Myeloma (NCT02955550) 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Friday Scientific Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• In Vivo Evaluation of Novel Geranylgeranyl Diphosphate Synthase InhibitorsClinically Relevant Abstract 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018