Saranya Chumsri MD

Breast Cancer, Hematologic Oncology

Associate Professor, Mayo Clinic

4500 San Pablo Road SJacksonville, FL 32224

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Summary

Saranya Chumsri, M.D. is an expert in breast cancer research. Her research is focusing on several aspects of breast cancer, including genomics, immunologic, epigenetics, breast cancer stem cells, endocrine resistance, as well as an aggressive form of breast cancer lacking estrogen receptor, progesterone receptor, and HER2, termed triple-negative breast cancer (TNBC). Dr. Chumsri also is an expert in developing genomic biomarkers, using RNA-seq and NanoString technologies, to predict response to targeted therapy in breast cancer, particularly immune-related biomarkers, as well as to identify mechanisms of resistance to targeted therapy. Furthermore, she also developed multiple novel experimental therapeutics in breast cancer through phase I and II clinical trials with a specific focus on immunotherapy, cancer vaccines, TNBC, and endocrine-resistant breast cancer. Combinatorial studies to evaluate the benefit of combining novel therapies in both preclinical and clinical trials.
As a part of her focus on breast cancer research, Dr. Chumsri is a clinician scientist reviewer for the Breast Cancer Research Program (BCRP) for the Department of Defense Congressionally Directed Medical Research Programs (CDMRP). She was also the Co-leader disease-oriented group: breast cancer for the University of Chicago Phase II Consortium (P2C) between 2011-2014. Furthermore, Dr. Chumsri also receives several funding supports from the Department of Defense, National Cancer Institute, Foundations, and pharmaceutical companies to conduct novel clinical trials in Immuno Oncology as well as Cancer Vaccine for both treatment and prevention of breast cancer. Currently, Dr. Chumsri is serving as the leader in the Experimental Trials for Precision Medicine at the Jacoby Center for Breast Health at Mayo Clinic Florida. Dr. Chumsri also serve in several important committees at Mayo Clinic Florida, including Cancer Center Scientific Progress Review Subcommittee, Fellowship Program Education Committe

Dr. Chumsri - Medical Oncologist & Breast Cancer Treatment - Mayo Clinic

A diagnosis of cancer is often followed by myriad doctor appointments and many questions.Dr. Saranya Chumsri, a medical oncologist, typically sees women afte...

Dr. Chumsri - Breast cancer and COVID19

The COVID-19 pandemic has made it difficult for some patients to keep on track with their regular breast cancer screenings. In the beginning of the pandemic,...

Education & Training

University of MarylandFellowship, Hematology and Medical Oncology, 2005 - 2008
Jefferson Health Medical Education/Jefferson Einstein Philadelphia HospitalResidency, Internal Medicine, 2002 - 2005
Chulalongkorn University Faculty of MedicineClass of 1999

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Certifications & Licensure

FL State Medical License 2014 - 2028
MD State Medical License 2008 - 2028
SC State Medical License 2024 - 2027
PA State Medical License 2002 - 2005
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Outstanding Research Award Mayo Clinic, 2019
The Physician Colleague (Attending) - Special Achievement Award, Nursing Excellence Awards University of Maryland Medical Center, 2013
Sonia Stupniker, M.D. Library Award, In Recognition of Outstanding Achievement in Scholarly Activity Albert Einstein Medical Center, 2005

Clinical Trials

GCC 0845:Vorinostat and Lapatinib in Advanced Solid Tumors and Advanced Breast Cancer to Evaluate Response and Biomarkers
TERMINATED
PHASE1, PHASE2
Entinostat and Anastrozole in Treating Postmenopausal Women With TNBC That Can Be Removed by Surgery
TERMINATED
PHASE2
Letrozole and Lapatinib Followed by Everolimus in Women With Advanced Breast Cancer
TERMINATED
PHASE2

Publications & Presentations

PubMed

1 citations
Postbiotics Against Breast Cancer: A Narrative Review Bridging Preclinical Evidence with Potential Clinical Application.
Chiara Luongo, Roberta Di Santillo, Alessia Cadavere, Franca Oglio, Laura Pisapia
Cancers. 2026-08-03
Postmastectomy radiation therapy in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer: a retrospective exploratory cohort analysis o...
Maria Carmen De Santis, Christine Campbell, Faye Samy, Fiorenza De Rose, Bruno Meduri
Eclinicalmedicine. 2026-08-01
Spatially resolved single-cell landscape of tumor immunotypes reveals the central role of interferon signaling and plasmacytoid dendritic cells in triple-negative brea...
Yi Liu, Jodi M Carter, Yaohua Ma, Sachin K Deshmukh, George W Sledge Jr
Journal for Immunotherapy of Cancer. 2026-06-03

Journal Articles

Chemotherapy dose reduction due to chemotherapy induced peripheral neuropathy in breast cancer patients receiving chemotherapy in the neoadjuvant or adjuvant settings:...
Bhatnagar B, Gilmore S, Goloubeva O, Pelser C, Medeiros M, Chumsri S, Tkaczuk K, Edelman M, Bao T, Springerplus, 7/1/2014
Guha P, Bandyopadhyaya G, Polumuri SK, Chumsri S, Gade P, Kalvakolanu DV, Ahmed H, Breast Cancer Res Treat, 5/1/2014
Circulating Giant Macrophages as a Potential Biomarker of Solid Tumors
Adams D, Martin S, Alpaugh K, Charpentier M, Tsai S, Bergan R, Ogden IM, Catalona W, Chumsri S, Tang CM, Cristofanilli, Proc Natl Acad Sci USA, 2/18/2014

Books/Book Chapters

Estrogen Action, SERMS and Women’s Health
Chapter: Advances with Aromatase Inhibitors.
Chumsri S, Bao T, Sabnis G, Brodie AEditors: V. Craig Jordan.World Scientific, Singapore2011
AACR Educational Book
Chapter: Review Article: Leukemic stem cell pathways – therapeutic implications.
Chumsri S, Matsui W, Burger AM2008
Cancer Research Journal
Chapter: Cancer stem cells.
Page 1935 - 2506Chumsri S, Burger AMEditors: Frank Columbus.Nova Science Publishers, Inc.2008

Abstracts/Posters

Cancer in HIV-Positive Women: Clinicopathologic Features and Comparison with General Population.
Kokh D, Rosenblatt R, Chumsri S, Kesmodel S, Ioffe O, The United States & Canadian Academy of Pathology’s 103rd Annual Meeting, 1/1/2014
Effect of diet-induced obesity on MCF-7Ca xenografts grown in ovariectomized athymic nude mice.
Sabnis G, Goloubeva O, Shah P, Chumsri S, Brodie A, AACR Annual Meeting, 1/1/2014
HER2 regulated miRNA expression in letrozole resistant breast cancer.
Kazi A, Sabnis G, Zhou Q, Chumsri S, Schech A, Shah P, Brodie A, AACR Annual Meeting, 1/1/2014

Lectures

Effects of immune architecture on response to adjuvant capecitabine in triple-negative breast cancer (FinXX trial).
2019 ASCO Annual Meeting - 6/1/2019
Association between adaptive immune signature and outcome in HER2-positive breast cancer treated with trastuzumab and lapatinib in the NCCTG-N9831 (Alliance) and NeoAL...
2018 ASCO Annual Meeting - Chicago, Illinois - 06/2/2018
Balancing Efficacy with Tolerability in the Management of Metastatic Breast Cancer
Florida Hospital Fish Memorial Cancer Institute, Orange City, FL - 5/9/2014

Press Mentions

Mayo Clinic Leads 4 Decades of Advances in Breast Cancer CareOctober 2nd, 2025
BriaCell Presents Benchmark Beating Survival and Clinical Benefit at AACR 2025; Advancements in Next Generation Bria-OTS+™ DevelopmentApril 28th, 2025
BriaCell 2024 SABCS® Spotlight Poster to Showcase Positive Overall Survival Data Across All Patient Subtypes in Metastatic Breast CancerNovember 26th, 2024

Grant Support

Early Therapeutics Development with Phase 2 EmphasisNIH2013–2014

Committees

Committee member, Mayo Clinic Florida Clinical Trials Leadership Council 2020 - Present
Committee member, Mayo Clinic Florida Fellowship Program Education Committee 2020 - Present
Committee member, Mayo Clinic Florida Fellowship Interview Committee 2019 - Present
Committee member, (Neo)ALTTO steering committee 2019 - Present
Committee member, ACCRU Consortium Breast Cancer Committee 2019 - Present

Professional Memberships

American Society of Clinical Oncology - ASCO
Member
American Association for Cancer Research - AACR
Member

Other Languages

Thai

External Links

Mayo Clinic Biohttps://www.mayoclinic.org/biographies/chumsri-saranya-m-d/bio-20114242
Refer a Patienthttp://www.mayoclinic.org/medical-professionals/provider-relations/refer-a-patient