ScottAFosterMD

PubMed

• 60 citations
  Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
  Dan Lu, Jennifer Y. Hsiao, Norman E. Davey, Vanessa A. Van Voorhis, Scott A. Foster, Chao Tang, David O. Morgan> ;The Journal of Cell Biology. 2014 Oct 13
• 112 citations
  Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572)...
  Brian A. Johns, Takashi Kawasuji, Teruhiko Taishi, David Temelkoff, Hiroshi Yoshida, Akiyama Toshiyuki, Yoshiyuki Taoda, Hitoshi Murai, Ryuichi Kiyama, Masahiro Fuji, ...> ;Journal of Medicinal Chemistry. 2013 Jul 11
• 10 citations
  Naphthyridinone (NTD) integrase inhibitors: N1 protio and methyl combination substituent effects with C3 amide groups.
  Brian A. Johns, Takashi Kawasuji, Eric E. Boros, James B. Thompson, Cecilia S. Koble, Edward P. Garvey, Scott A. Foster, Jerry Jeffrey, Tamio Fujiwara> ;Bioorganic & Medicinal Chemistry Letters. 2013 Jan 15
• 97 citations
  The APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.
  Scott A. Foster, David O. Morgan> ;Molecular Cell. 2012 Sep 28
• 34 citations
  Ubiquitination of Cdc20 by the APC Occurs through an Intramolecular Mechanism
  Ian T. Foe, Scott A. Foster, Stephanie K. Cheung, Steven Z DeLuca, David O. Morgan, David P. Toczyski> ;Current Biology. 2011 Nov 22
• 5 citations
  Combining symmetry elements results in potent naphthyridinone (NTD) HIV-1 integrase inhibitors
  Brian A. Johns, Takashi Kawasuji, Eric E. Boros, James B. Thompson, Edward P. Garvey, Scott A. Foster, Jerry Jeffrey, Wayne H. Miller, Noriyuki Kurose, Kenichi Matsumu...> ;Bioorganic & Medicinal Chemistry Letters. 2011 Nov 1
• 306 citations
  In Vitro Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor
  Masanori Kobayashi, Tomokazu Yoshinaga, Takahiro Seki, Chiaki Wakasa-Morimoto, Kevin W. Brown, Robert G. Ferris, Scott A. Foster, Richard J. Hazen, Shigeru Miki, Akemi...> ;Antimicrobial Agents and Chemotherapy. 2011 Feb 1
• 74 citations
  Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin
  Monica C. Rodrigo-Brenni, Scott A. Foster, David O. Morgan> ;Molecular Cell. 2010 Aug 27
• 23 citations
  Biomechanical analysis comparing three C1-C2 transarticular screw salvaging fixation techniques.
  Hossein Elgafy, Tejaswy Potluri, Vijay K. Goel, Scott Foster, Ahmad Faizan, Nikhil Kulkarni> ;Spine. 2010 Feb 15
• 13 citations
  Pharmacovirological Impact of an Integrase Inhibitor on Human Immunodeficiency Virus Type 1 cDNA Species In Vivo
  Christine Goffinet, Ina Allespach, Lena Oberbremer, Pamela L. Golden, Scott A. Foster, Brian A. Johns, Steven J. Novick, Karen Chiswell, Edward P. Garvey, Oliver T. Ke...> ;Journal of Virology. 2009 Aug 1
• 23 citations
  Synthesis and antiviral activity of 7-benzyl-4-hydroxy-1,5-naphthyridin-2(1H)-one HIV integrase inhibitors.
  Eric E. Boros, Cynthia E. Edwards, Scott A. Foster, Masahiro Fuji, Tamio Fujiwara, Edward P. Garvey, Pamela L. Golden, Richard J. Hazen, Jerry Jeffrey, Brian A. Johns,...> ;Journal of Medicinal Chemistry. 2009 Apr 17
• 55 citations
  The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore.
  Brian A. Johns, Scott H. Allen, James B. Thompson, Edward P. Garvey, Scott A. Foster, Jerry Jeffrey, Wayne H. Miller> ;Bioorganic & Medicinal Chemistry Letters. 2009 Mar 15
• 32 citations
  1,3,4-Oxadiazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 2: SAR of the C5 position.
  Brian A. Johns, Scott H. Allen, James B. Thompson, Edward P. Garvey, Scott A. Foster, Jerry Jeffrey, Wayne H. Miller> ;Bioorganic & Medicinal Chemistry Letters. 2009 Mar 15
• 43 citations
  Secondary mutations in viruses resistant to HIV-1 integrase inhibitors that restore viral infectivity and replication kinetics.
  Koichiro Nakahara, Chiaki Wakasa-Morimoto, Masanori Kobayashi, Shigeru Miki, Takeshi Noshi, Takahiro Seki, Mikiko Kanamori-Koyama, Shinobu Kawauchi, Akemi Suyama, Tosh...> ;Antiviral Research. 2009 Feb 1
• 87 citations
  Selection of diverse and clinically relevant integrase inhibitor-resistant human immunodeficiency virus type 1 mutants.
  Masanori Kobayashi, Koichiro Nakahara, Takahiro Seki, Shigeru Miki, Shinobu Kawauchi, Akemi Suyama, Chiaki Wakasa-Morimoto, Makoto Kodama, Takeshi Endoh, Eiichi Oosugi...> ;Antiviral Research. 2008 Nov 1
• 46 citations
  Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1
  Jill E. Chrencik, Alexei Brooun, Hui Zhang, Irimpan I. Mathews, Greg L. Hura, Scott A. Foster, J. Jefferson P. Perry, Markus Streiff, Paul Ramage, Hans Widmer, Gary M....> ;Journal of Molecular Biology. 2008 Jul 25
• 53 citations
  The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral
  Edward P. Garvey, Brian A. Johns, Margaret Gartland, Scott A. Foster, Wayne H. Miller, Robert G. Ferris, Richard Hazen, Mark R. Underwood, Eric E. Boros, James B. Thom...> ;Antimicrobial Agents and Chemotherapy. 2008 Mar 1
• 7 citations
  Remedial strategies in structural proteomics: Expression, purification, and crystallization of the Vav1/Rac1 complex
  Alexei Brooun, Scott A. Foster, Jill E. Chrencik, Ellen Y.T. Chien, Anand Kolatkar, Markus Streiff, Paul Ramage, Hans Widmer, Gisbert Weckbecker, Peter Kuhn> ;Protein Expression and Purification. 2007 May 1
• 110 citations
  Crystal Structure of LAAO from Calloselasma rhodostoma with an L-Phenylalanine Substrate: Insights into Structure and Mechanism
  Ibrahim M. Moustafa, Scott Foster, Artem Y. Lyubimov, Alice Vrielink> ;Journal of Molecular Biology. 2006 Dec 15
• 159 citations
  The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest.
  Scott A. Foster, G W Demers, B G Etscheid, Denise A. Galloway> ;Journal of Virology. 1994 Sep 1
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