ScottAlanPeslakMDPhD

PubMed

• Let-7 miRNAs repress HIC2 to regulate BCL11A transcription and hemoglobin switching.
  Peng Huang, Scott A Peslak, Vanessa Shehu, Cheryl A Keller, Belinda M Giardine, Junwei Shi, Ross C Hardison, Gerd A Blobel, Eugene Khandros> ;Blood. 2024 Feb 16
• Expansion of human hematopoietic stem cells by inhibiting translation.
  Li, C., Shin, H., Bhavanasi, D., Liu, M., Yu, X., Liu, X., Alvarez-Dominguez, J., Blobel, G., Gregory, B., Huang, J., Peslak, S., Klein, P.> ;Biorxiv. 2023 Nov 29
• 6 citations
  Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts.
  Vera Adema, Feiyang Ma, Rashmi Kanagal-Shamanna, Natthakan Thongon, Guillermo Montalban-Bravo, Hui Yang, Scott A Peslak, Feng Wang, Pamela Acha, Francesc Sole, Pamela ...> ;Blood Cancer Discovery. 2022 Nov 2
• 36 citations
  The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression
  Scott A. Peslak, Xianjiang Lan, Eugene Khandros, Jennifer A. Yano, Malini Sharma, Cheryl A. Keller, Belinda Giardine, Kunhua Qin, Osheiza Abdulmalik, Ross C. Hardison,...> ;Blood. 2020 Jun 11
• Diagnosis and Treatment of Aplastic Anemia.
  Peslak, S. A.,Olson, T.,Babushok, D. V.> ;Curr Treat Options Oncol. 2017 Nov 17
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Abstracts/Posters

• Heme-Regulated Inhibitor (HRI) Activates Transcription Factor ATF4 to Promote BCL11A Transcription and Fetal Hemoglobin Silencing
  Scott A. Peslak, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Implementation of an Evidence-Based Care Pathway for Emergency Department Management of Sickle Cell Vaso-Occlusive Crisis Leads to Improved Clinical Outcomes
  Scott A. Peslak, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Understanding Heterogeneity of Fetal Hemoglobin Induction through Comparative Analysis of Stage-Matched F- and a-Cells
  Scott A. Peslak, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

Lectures

• Heme-Regulated Inhibitor (HRI) Depletion Cooperates with Pharmacologic Inducers to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019