ScottRunyonMD

PubMed

• 6 citations
  Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
  Justas V Rodarte, Carly Baehr, Dustin Hicks, Tyler L Liban, Connor Weidle, Peter B Rupert, Rajwana Jahan, Abigail Wall, Andrew T McGuire, Roland K Strong, Scott Runyon...> ;Structure. 2023 Jan 5
• 8 citations
  Efficacy and Selectivity of Monovalent and Bivalent Vaccination Strategies to Protect against Exposure to Carfentanil, Fentanyl, and Their Mixtures in Rats.
  Bethany Crouse, Mariah M Wu, Valeria Gradinati, Andrew J Kassick, Daihyun Song, Rajwana Jahan, Saadyah Averick, Scott Runyon, Sandra D Comer, Marco Pravetoni> ;ACS Pharmacology & Translational Science. 2022 May 13
• 22 citations
  Therapeutic and Prophylactic Vaccines to Counteract Fentanyl Use Disorders and Toxicity.
  Christine Robinson, Valeria Gradinati, Fatima Hamid, Carly Baehr, Bethany Crouse, Saadyah Averick, Marina Kovaliov, Danni L. Harris, Scott P. Runyon, Federico Baruffal...> ;Journal of Medicinal Chemistry. 2020 Nov 20
• 4 citations
  Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists.
  George S. Amato, Amruta Manke, Vineetha Vasukuttan, Robert W. Wiethe, Rodney W. Snyder, Scott P. Runyon, Rangan Maitra> ;Bioorganic & Medicinal Chemistry. 2018 Aug 15
• 6 citations
  Anti-Müllerian hormone as a biomarker for acute testicular degeneration caused by toxic insults to stallion testes.
  Malgorzata A. Pozor, Alan J Conley, Janet F. Roser, Maggie Nolin, Gina L. Zambrano, Scott P. Runyon, Audrey A. Kelleman, Margo L. Macpherson> ;Theriogenology. 2018 Aug 1
• 35 citations
  Opioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in Rats
  Michael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, S. Winston...> ;The Journal of Pharmacology and Experimental Therapeutics. 2018 Jan 1
• 55 citations
  Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse
  Michael D. Raleigh, Samantha J. Peterson, Megan Laudenbach, Federico Baruffaldi, Frank I. Carroll, Sandra D. Comer, Hernán A. Navarro, Tiffany L. Langston, Scott P. Ru...> ;Plos One. 2017 Dec 1
• Through the Looking Glass: Specialty Influence on SCS Outcomes.
  Richard L. Boortz-Marx, M. Yawar J. Qadri, Lance Roy, Jason E. Pope, Timothy R. Deer, Scott L. Runyon> ;Neuromodulation. 2017 Oct 1
• 22 citations
  Discovery of a novel small molecule agonist scaffold for the APJ receptor.
  Sanju Narayanan, Rangan Maitra, Jeffery R. Deschamps, Katherine Bortoff, James B. Thomas, Yanyan Zhang, Keith R. Warner, Vineetha Vasukuttan, Ann M. Decker, Scott P. R...> ;Bioorganic & Medicinal Chemistry. 2016 Aug 15
• 4 citations
  Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene b...
  Chad M. Kormos, Moses G. Gichinga, Scott P. Runyon, James B. Thomas, S. Wayne Mascarella, Ann M. Decker, Hernán A. Navarro, F. Ivy Carroll> ;Bioorganic & Medicinal Chemistry. 2016 Aug 15
• 7 citations
  Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor Antagonists.
  Scott P. Runyon, Chad M. Kormos, Moses G. Gichinga, S. Wayne Mascarella, Hernán A. Navarro, Jeffrey R. Deschamps, Gregory H. Imler, F. Ivy Carroll> ;The Journal of Organic Chemistry. 2016 Aug 2
• 6 citations
  Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Ant...
  James B. Thomas, Mélanie Vivancos, Angela M. Giddings, Robert W. Wiethe, Keith R. Warner, Alexandre Murza, Élie Besserer-Offroy, Jean-Michel Longpré, Scott P. Runyon, ...> ;ACS Chemical Neuroscience. 2016 Jul 13
• 4 citations
  Thoracic Nerve Root Entrapment by Intrathecal Catheter Coiling: Case Report and Review of the Literature.
  Jing L. Han, Daniel B. Loriaux, Caroline Tybout, Merritt D. Kinon, Shervin Rahimpour, Scott L. Runyon, Thomas J. Hopkins, Richard L. Boortz-Marx, Shivanand P. Lad> ;Pain Physician. 2016 Mar 1
• 13 citations
  The frequency of early-activated hapten-specific B cell subsets predicts the efficacy of vaccines for nicotine dependence
  Megan Laudenbach, A.M. Tucker, Scott P. Runyon, Frank I. Carroll, Marco Pravetoni> ;Vaccine. 2015 Nov 17
• 12 citations
  Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3- and 4-methyl substituents.
  F. Ivy Carroll, Moses G. Gichinga, Chad M. Kormos, Rangan Maitra, Scott P. Runyon, James B. Thomas, S. Wayne Mascarella, Ann M. Decker, Hernán A. Navarro> ;Bioorganic & Medicinal Chemistry. 2015 Oct 1
• 14 citations
  The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.
  David A. Perrey, Ann M. Decker, Jun-Xu Li, Brian P. Gilmour, Brian F. Thomas, Danni L. Harris, Scott P. Runyon, Yanan Zhang> ;Bioorganic & Medicinal Chemistry. 2015 Sep 1
• 37 citations
  Regulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery.
  Sanju Narayanan, Danni L. Harris, Rangan Maitra, Scott P. Runyon> ;Journal of Medicinal Chemistry. 2015 Jul 10
• 2 citations
  The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the Neurotensin receptor type 2
  James B. Thomas, Angela M. Giddings, Srinivas Olepu, Robert W. Wiethe, Keith R. Warner, Philippe Sarret, Jean-Michel Longpré, Scott P. Runyon, Brian P. Gilmour> ;Bioorganic & Medicinal Chemistry Letters. 2015 May 15
• 11 citations
  Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor.
  David A. Perrey, Nadezhda German, Ann M. Decker, David A. Thorn, Jun-Xu Li, Brian P. Gilmour, Brian F. Thomas, Danni L. Harris, Scott P. Runyon, Yanan Zhang> ;ACS Chemical Neuroscience. 2015 Feb 12
• 5 citations
  Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin recept...
  James B. Thomas, Angela M. Giddings, Srinivas Olepu, Robert W. Wiethe, Danni L. Harris, Sanju Narayanan, Keith R. Warner, Philippe Sarret, Jean-Michel Longpré, Scott P...> ;Bioorganic & Medicinal Chemistry Letters. 2015 Jan 15
• 17 citations
  Effects of the neuropeptide S receptor antagonist RTI-118 on abuse-related facilitation of intracranial self-stimulation produced by cocaine and methylenedioxypyrovale...
  J S Bonano, Scott P. Runyon, Carla Hassler, Richard A. Glennon, S. Stevens Negus> ;European Journal of Pharmacology. 2014 Nov 15
• 12 citations
  Identification of N-[(5-{[(4-Methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl] -l-leucine (NTRC-824), a Neurotensin-like Nonpeptide Compound Selec...
  James B. Thomas, Angela M. Giddings, Robert W. Wiethe, Srinivas Olepu, Keith R. Warner, Philippe Sarret, Louis Gendron, Jean-Michel Longpré, Yanan Zhang, Scott P. Runy...> ;Journal of Medicinal Chemistry. 2014 Sep 11
• 18 citations
  Design, synthesis, and biological evaluation of (3R)-1,2,3,4-tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpr...
  Chad M. Kormos, Moses G. Gichinga, Rangan Maitra, Scott P. Runyon, James B. Thomas, Lawrence E. Brieaddy, S. Wayne Mascarella, Hernán A. Navarro, F. Ivy Carroll> ;Journal of Medicinal Chemistry. 2014 Aug 25
• 11 citations
  Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluation.
  Carla Hassler, Yanan Zhang, Brian P. Gilmour, Tyler N. Graf, Timothy R. Fennell, Rodney W. Snyder, Jeffrey R. Deschamps, Rainer K. Reinscheid, Celia Garau, Scott P. Ru...> ;ACS Chemical Neuroscience. 2014 Jul 11
• 14 citations
  Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor...
  James B. Thomas, Angela M. Giddings, Robert W. Wiethe, Srinivas Olepu, Keith R. Warner, Philippe Sarret, Louis Gendron, Jean-Michel Longpré, Yanan Zhang, Scott P. Runy...> ;Journal of Medicinal Chemistry. 2014 Jun 5
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