Scott Brian Snapper MD PhD
Inflammatory Bowel Disease
Chief, Division of GI, Hepatology, & Nutrition; Wolpow Family Chair in IBD Treatment and Research, Boston Children's Hospital; Egan Family Professor of Pediatrics in the Field of Transitional Medicine and Professor of Medicine, Harvard Medical School
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300 Longwood AveBoston, MA 02115
Phone+1 617-919-4973
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Education & Training
Mass General Brigham/Massachusetts General HospitalFellowship, Gastroenterology, 1993 - 1997
Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 1990 - 1993
Albert Einstein College of MedicineClass of 1990
Certifications & Licensure
MA State Medical License 1992 - 2026
American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification Longitudinal Medical Record, Partners Healthcare System, 2012, 2014-2017
- CMS Meaningful Use Stage 1 Certification Partners Longitudinal Medical Record, Partners Healthcare System, 2012, 2014-2017
- CMS Meaningful Use Stage 2 Certification OpTime Surgical 2014 Certified Module, Epic Systems Corporation, 2012, 2014-2017
Clinical Trials
- Oral OKT3 for the Treatment of Active Ulcerative Colitis Start of enrollment: 2011 Apr 07
- Low Dose IL-2 for Ulcerative Colitis
- Low Dose IL-2 for the Treatment of Crohn's Disease Start of enrollment: 2021 Mar 11
Publications & Presentations
PubMed
- Childhood exposure to a sibling with Crohn's disease alters gut microbiome and Crohn's disease susceptibility.Rirong Chen, Hyun Jung Kim, Maham Bushra, Cong Phi Dang, Qilong Li
Gut. 2026-08-25 - Neutralising autoantibodies against IL-10 and HLA-DRB1*01:03 in paediatric patients with inflammatory bowel disease.Nima Gharahdaghi, Pai-Jui Yeh, Katherine Vadakethala, Madeleine Coy, Ladan Kabiri
Gut. 2026-08-11 - Purine and pyrimidine-based bacterial cyclic dinucleotides egress the phagosome and activate the innate immune sensor STING.Stephanie A Ragland, Katherine E Lindblad, Yao Li, Joon H Choi, Daniel Okin
Immunity. 2026-08-11
Journal Articles
- Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte–Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn’s DiseaseLee A Denson, Bruce J Aronow, Barbara S Kirschner, Joshua D Noe, Melvin B Heyman, Ramnik J Xavier, Robert N Baldassano, Jeffrey S Hyams, Subra Kugathasan, Wallace V Cr..., Inflammatory Bowel Diseases
- Mucosal Gene Expression in Pediatric and Adult Patients with Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic AnalysisAthos Bousvaros, Scott B Snapper, Jodie Ouahed, Inflammatory Bowel Diseases
- The Treatment of Inflammatory Bowel Disease in Patients with Selected Primary ImmunodeficienciesScott Snapper, MD, Journal of Clinical Immunology
Other
- Increased Risk for Malignancies in 131 Affected CTLA4 Mutation CarriersScott Snapper, MD, Frontiers in Neurology
https://www.doximity.com/articles/50e86467-0edf-46ac-a42c-04b98941286b
UpToDate, Wolters Kluwer Health - 2011-04-29 - Increased Risk for Malignancies in 131 Affected CTLA4 Mutation CarriersScott Snapper, MD, Frontiers in Neurology
https://www.doximity.com/articles/50e86467-0edf-46ac-a42c-04b98941286b
UpToDate, Wolters Kluwer Health - 2012-01-09
Authored Content
- CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and ThrombosisJune 2017
Press Mentions
Health Rounds: Roche/BioNTech Experimental Vaccine Shows Early Promise in Pancreatic CancerMarch 5th, 2025- A Surprising Link Between Epstein-Barr Virus & Crohn's Is RevealedMarch 5th, 2025
- Epstein-Barr Virus Infection Predisposes People to Develop Crohn's DiseaseMarch 2nd, 2025
Grant Support
- Training in Pediatric Gastroenterology, Hepatology, and NutritionBOSTON CHILDREN'S HOSPITAL1983–2029
- Type III interferon Control of Mucosal ImmunityBOSTON CHILDREN'S HOSPITAL2017–2026
- Type III interferon Control of Mucosal ImmunityBOSTON CHILDREN'S HOSPITAL2017–2026
- Identifying Immune and Epithelial Network Signatures in Very Early Onset Inflammatory Bowel DiseaseBOSTON CHILDREN'S HOSPITAL2020–2025
- Low Dose Interleukin-2 for Regulatory T cell Modulation and the Treatment of Crohnâs DiseaseBOSTON CHILDREN'S HOSPITAL2020–2025
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