ScottEricStromeMD

Otolaryngology (ENT) • Baltimore, MD

Professor of Otolaryngology, University MD School of Medicine

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Office
22 S Greene St
Baltimore, MD 21201
Phone(410) 328-6897
Fax(410) 328-2109
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Education & Training

University of Michigan Hospitals and Health CentersResidency, Otolaryngology, 1992 - 1997
University of Michigan Hospitals and Health CentersInternship, Transitional Year, 1991 - 1992
Harvard Medical SchoolClass of 1991

Certifications & Licensure

TN State Medical License 2018 - 2021
MD State Medical License 2005 - 2019
MN State Medical License 1998 - 2005
PA State Medical License 1997 - 1998
OH State Medical License 1992 - 1994
American Board of Otolaryngology - Head and Neck Surgery Otolaryngology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2007-2014
America's Top Doctors for Cancer Castle Connolly, 2009-2013
Top Doctors:Baltimore Area Castle Connolly, 2012
Top Doctors:Washington-Baltimore Castle Connolly, 2012
Fellow (FAAO-HNS) American Academy of Otolaryngology - Head and Neck Surgery
Whos Who in Medicine and Healthcare Marquis Whos Who
Super Doctor SuperDoctors.com
Fellow (FACS) American College of Surgeons
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Clinical Trials

A Phase 1 Open Label, Dose Escalation Study to Evaluate the Effect of Four Doses of MAGE-A3/HPV 16 Trojan Peptides 0001 and 0002 Administered Subcutaneously Start of enrollment: 2009 Jul 01DeSanto, J.,Edelman, M.J.
A Phase 1 Open Label, Dose Escalation Study to Evaluate the Effect of Four Doses of MAGE-A3/HPV 16 Trojan Peptides 0001 and 0002 Administered Subcutaneously in Combination With Montanide and GM-CSF on Immunological Response, Safety, Tolerability, and Prel Start of enrollment: 2005 Nov 01DeSanto, J.M.,Edelman, M.J.,Strome, S.E.

Publications & Presentations

PubMed

Intratumor genetic heterogeneity in squamous cell carcinoma of the oral cavity
Dan P. Zandberg, Luke J. Tallon, Sushma Nagaraj, Lisa Sadzewicz, Yuji Zhang, Maxwell B. Strome, Xuechu E. Zhao, Kranthi Vavikolanu, Xiaoyu Zhang, John C. Papadimitriou...> ;Head and Neck-journal for The Sciences and Specialties of The Head and Neck. 2019 Aug 1
NK cell expression of Tim-3: First impressions matter.
Edward So, Ariana Khaladj-Ghom, Yaping Ji, Julian D Amin, Yang Song, Erin Burch, Hua Zhou, Haoping Sun, Shaodong Chen, Søren M. Bentzen, Ronna Hertzano, Xiaoyu Zhang, ...> ;Immunobiology. 2019 Mar 2
A recombinant human IgG1 Fc multimer designed to mimic the active fraction of IVIG in autoimmunity
Xiaoyu Zhang, Jane Owens, Henrik S. Olsen, Edward So, Erin Burch, Mark C McCroskey, Xianfeng Li, Gregory Weber, Donald Bennett, Denis Rybin, Hua Zhou, Haiping Hao, Emm...> ;JCI insight. 2019 Jan 24
The evolving role of immuno‐oncology for the treatment of head and neck cancer
Arianna L. Strome, Xiaoyu Zhang, Scott E. Strome> ;Laryngoscope investigative otolaryngology. 2019 Jan 10
Is routine genetic testing warranted in head and neck paragangliomas?
Gupta, N., Strome, S. E., Hatten, K. M.> ;The Laryngoscope. 2018 Dec 28
A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b.
Zhou, H., Olsen, H. S., So, E., Mérigeon, E. Y., Rybin, D., Owens, J., LaRosa, G., Block, D. S., Strome, S. E., Zhang, X.> ;Blood advances. 2018 Jan 4
Recombinant human IgG1 based Fc multimers, with limited FcR binding capacity, can effectively inhibit complement-mediated disease.
Sun, H., Olsen, H. S., Mérigeon, E. Y., So, E., Burch, E., Kinsey, S., Papadimitriou, J. C., Drachenberg, C. B., Bentzen, S. M., Block, D. S., Strome, S. E., Zhang, X.> ;Journal of autoimmunity. 2017 Aug 24
8 citations
Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting
Julie E. Bauman, Ezra E.W. Cohen, Robert L. Ferris, David J. Adelstein, David M. Brizel, John A. Ridge, Brian O'Sullivan, Barbara Burtness, Lisa H. Butterfield, Willia...> ;Cancer. 2017 Apr 1
Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model.
Ditza Levin, H. A. D. Lagassé, E. Burch, S. Strome, S. Tan, H. Jiang, Zuben E. Sauna, Basil Golding> ;Journal of Thrombosis and Haemostasis. 2017 Apr 1
What additional treatment is indicated for oral cavity cancer with isolated perineural invasion?
Hatten, K. M., Gupta, N., Strome, S. E.> ;The Laryngoscope. 2017 Mar 30
The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment.
Sara I. Pai, Dan P. Zandberg, Scott E. Strome> ;Oral Oncology. 2016 Oct 1
7 citations
Oropharyngeal cancer as a driver of racial outcome disparities in squamous cell carcinoma of the head and neck: 10-year experience at the University of Maryland Greene...
Dan P. Zandberg, Sandy Liu, Olga Goloubeva, Robert A. Ord, Scott E. Strome, Mohan Suntharalingam, Rodney J. Taylor, Robert E. Morales, Jeffrey S. Wolf, Ann Zimrin, Jos...> ;Head and Neck-journal for The Sciences and Specialties of The Head and Neck. 2016 Apr 1
Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune Disease.
Xiaoyu Zhang, Henrik S. Olsen, Shaodong Chen, Edward So, Hua Zhou, Erin Burch, Emmanuel Y. Mérigeon, David S. Block, Scott E. Strome> ;Journal of Immunology. 2016 Feb 1
Impact of Detachment Methods on M2 Macrophage Phenotype and Function.
Shaodong Chen, Edward So, Scott E. Strome, Xiaoyu Zhang> ;Journal of Immunological Methods. 2015 Nov 1
12 citations
RFX transcription factors are essential for hearing in mice
Ran Elkon, Beatrice Milon, Laura Morrison, Manan U. Shah, Sarath Vijayakumar, Manoj Racherla, Carmen C. Leitch, Lorna E. Silipino, Shadan Hadi, Michèle Weiss-Gayet, Em...> ;Nature Communications. 2015 Oct 15
Invariant natural killer T cells generated from human adult hematopoietic stem-progenitor cells are poly-functional.
Wenji Sun, Yi Wang, James E. East, Amy S. Kimball, Katherine Tkaczuk, Susan B. Kesmodel, Scott E. Strome, Tonya J. Webb> ;Cytokine. 2015 Mar 1
14 citations
A Phase I Dose Escalation Trial of MAGE-A3 and HPV16 Specific Peptide Immunomodulatory Vaccines in Patients with Recurrent / Metastatic (RM) Squamous Cell Carcinoma of...
Dan P. Zandberg, Sandra Rollins, Olga Goloubeva, Robert E. Morales, Ming Tan, R. Taylor, Jeffrey S. Wolf, Lisa M. Schumaker, Kevin J. Cullen, Ann Zimrin, Robert A. Ord...> ;Cancer Immunology, Immunotherapy. 2015 Mar 1
Immature teratoma of the maxillary sinus: a rare pediatric tumor.
Alice E. Chang, Bryan T. Ambro, Scott E. Strome, John C. Papadimitriou, Kevin D. Pereira> ;Archives of Otolaryngology-head & Neck Surgery. 2014 Sep 1
42 citations
The role of the PD-L1:PD-1 pathway in squamous cell carcinoma of the head and neck.
Zandberg, D. P., Strome, S. E.> ;Oral oncology. 2014 May 14
In response to What are the best management strategies for radiation-induced xerostomia?
Christoph T. Hutchinson, Scott E. Strome, Mohan Suntharalingam> ;Laryngoscope. 2014 Apr 29
32 citations
Combination Immunotherapy after ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-Primed and Costimulated Autolo...
Aaron P. Rapoport, Nicole A. Aqui, Edward A. Stadtmauer, Dan T. Vogl, Yin Yan Xu, Michael Kalos, Ling Cai, Hong-Bin Fang, Brendan M. Weiss, Ashraf Badros, Saul Yanovic...> ;Clinical Cancer Research. 2014 Mar 1
2 citations
What are the best management strategies for radiation-induced xerostomia?
Christoph T. Hutchinson, Mohan Suntharalingam, Scott E. Strome> ;Laryngoscope. 2014 Feb 1
Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon...
Ajay N. Jain, Bhawna Poonia, Edward So, Ravi Vyzasatya, Erin Burch, Henrik S. Olsen, Emmanuel Y. Mérigeon, David S. Block, Xiaoyu Zhang, Dan H. Schulze, Nader Hanna, W...> ;European Journal of Cancer. 2013 Oct 1
Surgical management of craniofacial neurofibromatosis type 1 associated tumors.
Lindsay E. Janes, Jennifer Sabino, Jamil A. Matthews, John C. Papadimitriou, Scott E. Strome, Devinder P. Singh> ;Journal of Craniofacial Surgery. 2013 Jul 1
2 citations
A high throughput method for enrichment of natural killer cells and lymphocytes and assessment of in vitro cytotoxicity.
So, E. C., Sallin, M. A., Zhang, X., Chan, S. L., Sahni, L., Schulze, D. H., Davila, E., Strome, S. E., Jain, A. N.> ;Journal of immunological methods. 2013 May 18
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Press Mentions

Isolation, Snow Punching COVID Just When It’s WeakFebruary 19, 2021 13:45
Two-Thirds of Tennessee Residents over 70 Still Need COVID-19 VaccinationsFebruary 11, 2021 12:33
Doctors Suspect COVID Delayed Immune Response in Young Surgeon’s DeathFebruary 11, 2021 12:33
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Grant Support

Clinical Trial: Mage-A3/Hpv16 Peptide Immunotherapeutic Vaccines For Squamous CENational Center For Research Resources2008
0524gccNational Center For Research Resources2007
Mage-A3/Hpv 16 Peptide Vaccines For Squamous Cell Carcinoma Of The Head And NeckNational Center For Research Resources2006
Mage-A3/Hpv 16 Peptide Vaccines For Head And Neck CancerNational Institute Of Dental &Craniofacial Research2004–2006
Methods To Enhance Immunotherapy Of Head And Neck CancerNational Institute Of Dental &Craniofacial Research2004
Mage-A3/Hpv 16 Peptide Vaccines For Head And Neck CancerNational Institute Of Dental &Craniofacial Research2004
Methods To Enhance Immunotherapy Of Head And Neck CancerNational Institute Of Dental &Craniofacial Research2000–2003