SeanIsaacSavitzMD

Neurology • Houston, TX

Vascular Neurology

Professor and Frank M. Yatsu Chair in Neurology and Director, Institute for Stroke and Cerebrovascular Disease

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Office
UTHealth-Houston (Stroke Institute)
6410 Fannin St. Ste 1010
Houston, TX 77030
Phone+1 713-500-7092

Fax+1 713-500-7101
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Education & Training

Beth Israel Deaconess Medical Center/Harvard Medical SchoolResidency, Neurology, 2001 - 2004
Beth Israel Deaconess Medical CenterInternship, Internal Medicine, 2000 - 2001
Albert Einstein College of MedicineClass of 2000

Certifications & Licensure

TX State Medical License 2007 - 2024
MA State Medical License 2004 - 2007
American Board of Psychiatry and Neurology Neurology
American Board of Psychiatry and Neurology Vascular Neurology

Clinical Trials

Safety/Feasibility of Autologous Mononuclear Bone Marrow Cells in Stroke Patients Start of enrollment: 2009 Jan 01
Completed
Phase 1
Safety of Intravenous Thrombolysis for Wake-up Stroke Start of enrollment: 2010 Jul 01
Completed
Phase 2
Mesenchymal Stromal Cells for Ischemic Stroke Start of enrollment: 2016 Dec 01
Withdrawn
Phase 1, Phase 2
A Study of NCS-01 in Patients With Acute Ischemic Stroke Start of enrollment: 2020 Feb 27
Recruiting
Phase 1, Phase 2
Virtually Assisted Home Rehabilitation After Acute STroke (VAST-rehab) Start of enrollment: 2020 Apr 20
Completed
Not Applicable
Roles: Principal Investigator, Contact
CompARing Long terM Outcomes in Chronic Stroke Survivors Across Investigational Assessments Following a Prescribed Upper Extremity Exercise Program Start of enrollment: 2023 Feb 21
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials Start of enrollment: 2022 Jun 18
Recruiting
Roles: Principal Investigator, Contact
intenSive UpPer Extremity Recovery Program for Chronic Stroke (SUPER) Start of enrollment: 2023 Mar 20
Recruiting
Not Applicable
Roles: Contact, Principal Investigator
Virtually Assisted Home Rehabilitation After Acute Stroke-2 Start of enrollment: 2023 Mar 09
Completed
Not Applicable
Roles: Principal Investigator, Contact
Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium Start of enrollment: 2021 Sep 29
Recruiting
Roles: Contact
Non-invasive Trigeminal and Vagus Nerve Stimulation for Stroke Subjects With Chronic Upper Extremity Deficits Start of enrollment: 2024 Mar 05
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Comparing Stroke Risk Factors Among Sexual Minority Groups in Texas.
Krenek, B., Tundealao, S., Beauchamp, J., Tamí-Maury, I., Savitz, S.> ;International Journal of Behavioral Medicine. 2024 Feb 23
Regression analysis of multivariate recurrent event data allowing time-varying dependence with application to stroke registry data.
Li, W., Rahbar, M., Zhang, J., Kim Lundin, S., Tahanan, A., Ning, J., Savitz, S.> ;Statistical Methods in Medical Research. 2024 Feb 1
Multicenter exploration of tenecteplase transition factors: A quantitative analysis.
Sidarrth Prasad, Erica M Jones, Mehari Gebreyohanns, Yoon Kwon, DaiWai M Olson, Jane A Anderson, Sean I Savitz, Salvador Cruz-Flores, Steven J Warach, Charlotte E Rhod...> ;Journal of Stroke and Cerebrovascular Diseases. 2024 Apr 1
1 citations
Allogeneic Stem Cell Therapy for Acute Ischemic Stroke: The Phase 2/3 TREASURE Randomized Clinical Trial.
Houkin, K., Osanai, T., Uchiyama, S., Minematsu, K., Taguchi, A., Maruichi, K., Niiya, Y., Asaoka, K., Kuga, Y., Takizawa, K., Haraguchi, K., Yoshimura, S., Kimura, K....> ;JAMA Neurology. 2024 Feb 1
Autologous bone marrow mononuclear cells to treat severe traumatic brain injury in children.
Cox, C., Notrica, D., Juranek, J., Miller, J., Triolo, F., Kosmach, S., Savitz, S., Adelson, P., Pedroza, C., Olson, S., Scott, M., Kumar, A., Aertker, B., Caplan, H.,...> ;Brain. 2024 Jan 5
Feasibility and user-experience of a virtual environment for social connection and education after stroke: A pilot study.
Beauchamp, J., Wang, M., Leon Novelo, L., Cox, C., Meyer, T., Fagundes, C., Dishman, D., Johnson, C., Savitz, S., Sharrief, A.> ;Journal of Stroke and Cerebrovascular Diseases. 2024 Feb 1
2 citations
Dietary Intake and Quality among Stroke Survivors: NHANES 1999-2018.
Erika R Zoellner, Mindy A Patterson, Anjail Z Sharrief, Sean I Savitz, Wesley J Tucker, Derek C Miketinas> ;The Journal of Nutrition. 2023 Oct 1
aBnormal motION capture In aCute Stroke (BIONICS): A Low-Cost Tele-Evaluation Tool for Automated Assessment of Upper Extremity Function in Stroke Patients.
Syed A Zamin, Kaichen Tang, Emily A Stevens, Melissa Howard, Dorothea M Parker, Allyson Seals, Xiaoqian Jiang, Sean Savitz, Shayan Shams> ;Neurorehabilitation and Neural Repair. 2023 Sep 1
2 citations
Enhanced Cerebroprotection of Xenon-Loaded Liposomes in Combination with rtPA Thrombolysis for Embolic Ischemic Stroke.
Tao Peng, Keith Booher, Melanie R Moody, Xing Yin, Jaroslaw Aronowski, David D McPherson, Sean I Savitz, Hyunggun Kim, Shao-Ling Huang> ;Biomolecules. 2023 Aug 16
Hemostatic efficacy of four factor prothrombin complex concentrate in intracerebral hemorrhage patients receiving warfarin vs. factor Xa inhibitors.
Gregory Pon, Brittany Pelsue, Sujan Teegala Reddy, Kaushik Parsha, Xu Zhang, Brian Gulbis, Andrew Barreto, Sean I Savitz, Miguel Escobar, Teresa A Allison> ;Thrombosis Research. 2023 Sep 1
Longitudinal Morphometric Changes in the Corticospinal Tract Shape After Hemorrhagic Stroke.
Seth B Boren, Sean I Savitz, Nicole Gonzales, Khader Hasan, Andrea Becerril-Gaitan, Vahed Maroufy, Yuan Li, James Grotta, Emily A Steven, Clark W Sitton, Jaroslaw Aron...> ;Translational Stroke Research. 2023 Jun 13
1 citations
A National, Electronic Health Record-Based Study of Perinatal Hemorrhagic and Ischemic Stroke.
Stuart Fraser, Samantha M Levy, Yashar Talebi, Sean I Savitz, Alicia Zha, Gen Zhu, Hulin Wu> ;Journal of Child Neurology. 2023 Mar 1
2 citations
The International Stroke Recovery and Rehabilitation Alliance.
Julie Bernhardt, Dale Corbett, Sean Dukelow, Sean Savitz, John M Solomon, Rachel Stockley, Katharina S Sunnerhagen, Geert Verheyden, Marion Walker, Margit Alt Murphy, ...> ;The Lancet. Neurology. 2023 Apr 1
Inequities in Telemedicine Use Among Patients With Stroke and Cerebrovascular Diseases: A Tricenter Cross-sectional Study.
Imama A Naqvi, Audrey S Cohen, Youngran Kim, Jennifer Harris, Mary Carter Denny, Kevin Strobino, Nathan Bicher, Ryan A Leite, Dylan Sadowsky, Comfort Adegboye, Nnedinm...> ;Neurology. Clinical Practice. 2023 Apr 1
2 citations
Intra-arterial bone marrow mononuclear cells for stroke.
Sean I Savitz> ;The Lancet. Neurology. 2023 Feb 1
Feasibility of a meditation intervention for stroke survivors and informal caregivers: a randomized controlled trial.
Jennifer E S Beauchamp, Anjail Sharrief, Alejandro Chaoul, Tahani Casameni Montiel, Mary F Love, Stanley Cron, Alan Prossin, Sudhakar Selvaraj, Deniz Dishman, Sean I S...> ;BMC Psychology. 2023 Jan 12
An Intervention Mapping Approach to Developing a Stroke Literacy Video for Recent Stroke Survivors: Development and Usability Study.
Mary Carter Denny, Andrea Ancer Leal, Tahani Casameni Montiel, Keona J Wynne, Gabrielle Edquilang, Kim Yen Thi Vu, Farhaan Vahidy, Sean I Savitz, Jennifer Es Beauchamp...> ;JMIR Formative Research. 2023 Jan 4
11 citations
Cell-based therapies for neurological disorders - the bioreactor hypothesis.
Sean I Savitz, Charles S Cox Jr> ;Nature Reviews. Neurology. 2023 Jan 1
In Memoriam: Alexander W. Dromerick Jr, MD, July 1, 1958-August 21, 2021.
Sean I Savitz, Elissa L Newport, Dorothy Edwards> ;Stroke. 2022 Dec 1
Inpatient Teleneurology Follow-up Has Comparable Outcomes to In-Person Neurology Follow-up.
Alicia M Zha, Alyssa D Trevino, Christy M Ankrom, Kristie M Chu, Michele M Joseph, Tushar Patni, Tiffany D Cossey, Sean I Savitz, Tzu-Ching Wu, Amanda Jagolino-Cole> ;Neurology. Clinical Practice. 2022 Dec 1
4 citations
Personalizing repetitive transcranial magnetic stimulation for precision depression treatment based on functional brain network controllability and optimal control ana...
Feng Fang, Beata Godlewska, Raymond Y Cho, Sean I Savitz, Sudhakar Selvaraj, Yingchun Zhang> ;Neuroimage. 2022 Oct 15
Longitudinal Resting-State Functional Magnetic Resonance Imaging Study: A Seed-Based Connectivity Biomarker in Patients with Ischemic and Intracerebral Hemorrhage Stroke.
Seth B Boren, Sean I Savitz, Timothy M Ellmore, Octavio D Arevalo, Jaroslaw Aronowski, Christin Silos, Sarah George, Muhammad E Haque> ;Brain Connectivity. 2023 Oct 1
3 citations
Effects of escitalopram therapy on functional brain controllability in major depressive disorder.
Feng Fang, Beata Godlewska, Raymond Y Cho, Sean I Savitz, Sudhakar Selvaraj, Yingchun Zhang> ;Journal of Affective Disorders. 2022 Aug 1
8 citations
A multitask deep learning approach for pulmonary embolism detection and identification.
Xiaotian Ma, Emma C Ferguson, Xiaoqian Jiang, Sean I Savitz, Shayan Shams> ;Scientific Reports. 2022 Jul 29
22 citations
Telehealth for rehabilitation and recovery after stroke: State of the evidence and future directions.
Coralie English, Maria Gabriella Ceravolo, Simone Dorsch, Avril Drummond, Dorcas Bc Gandhi, Judith Halliday Green, Ben Schelfaut, Paul Verschure, Gerard Urimubenshi, S...> ;International Journal of Stroke. 2022 Jun 1
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Abstracts/Posters

Assessment and Reduction of Unnecessary Thrombophilia Testing in Patients 18-60 Years with Acute Cryptogenic Ischemic Stroke
Sean.I. Savitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

Cell Society 2nd Annual Clinical Meeting
Medical Education Advocates, Coronado, California - 2/17/2012
Discussant
Houston, TX - 2/13/2014

Other

Locked-in syndrome
Savitz SI, Caplan LR
http://www.uptodate.com/contents/locked-in-syndrome
UpToDate, Wolters Kluwer Health - 2013-03-07

Press Mentions

Athersys Provides MultiStem Clinical UpdateJanuary 9th, 2023
Sharrief Awarded $3.1M NIH Grant to Test Whether Telehealth Improves Racial Disparities in Outcomes for Stroke SurvivorsDecember 6th, 2021
COVID Help Desk: What Is COVID Brain Fog, and How Do I Know if I Have It?May 19th, 2021
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Grant Support

Cytoprotection With Autologous Mononuclear Cells For StrokeNational Institute Of Neurological Disorders And Stroke2011–2012
Safety/Feasibility Of Autologous Mononuclear Bone Marrow Cells In Stroke PatientsEunice Kennedy Shriver National Institute Of Child Health &Human Development2010–2011
Career DevelopmentNational Institute Of Neurological Disorders And Stroke2008–2011
Preclinical Development Of Bone Marrow Mononuclear Cell Therapy For Ischemic StroNational Institute Of Neurological Disorders And Stroke2008–2009