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1050 Brickell AveUnit 3018Miami, FL 33131
Phone+1 818-574-3062
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Summary
- Shaheen E. Lakhan, MD, PhD, FAAN, is a physician-scientist, entrepreneur, and biotech executive dedicated to advancing neuroscience and digital health innovation. He is the Founder of Boricua Bio, a Puerto Rico–based biotechnology company focused on building next-generation therapeutics at the intersection of brain, behavior, and technology.
Dr. Lakhan previously served as Chief Medical & Scientific Officer at Click Therapeutics, where he led the development of software-based prescription digital therapeutics across neurology, psychiatry, cardiometabolic, and oncology indications. Under his leadership, Click achieved multiple FDA clearances, Breakthrough Device designations, and pivotal partnerships with Boehringer Ingelheim, Otsuka, and Indivior.
Board-certified in neurology and pain medicine with training from the Cleveland Clinic and Massachusetts General Hospital, Dr. Lakhan has advanced novel drugs, devices, and digital therapeutics from concept to market. He has held leadership roles in academia and industry, including founding department chair and dean at the California University of Science and Medicine, and faculty appointments at Harvard Medical School and Case Western Reserve University.
He has authored over 100 peer-reviewed publications and books and has been recognized with the Harvard Medical School Dean’s Community Service Award, the U.S. Presidential Lifetime Achievement Award, and the Congressional Gold Medal. A Fellow of the American Academy of Neurology, Dr. Lakhan continues to integrate science, compassion, and innovation to democratize access to high-quality, data-driven healthcare.
Education & Training
Mass General Brigham/Massachusetts General HospitalFellowship, Pain Medicine, 2014 - 2015
Cleveland Clinic FoundationResidency, Internal Medicine, 2010 - 2014
Cleveland Clinic FoundationResidency, Neurology, 2010 - 2014
Technion-Israel Inst of Technology Faculty of MedicineClass of 2009, MD, Cum Laude
Certifications & Licensure
FL State Medical License 2021 - 2028
MI State Medical License 2022 - 2028
CO State Medical License 2022 - 2027
TX State Medical License 2022 - 2027
TN State Medical License 2024 - 2027
NJ State Medical License 2022 - 2027
MA State Medical License 2014 - 2027
American Board of Psychiatry and Neurology Neurology
American Board of Psychiatry and Neurology Pain Medicine- Join now to see all
Clinical Trials
- The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine Start of enrollment: 2012 Jul 01
- A Study to Evaluate the Safety, Tolerability, and Efficacy of SAGE-217 Compared to Placebo in Adult Participants With Comorbid Major Depressive Disorder (MDD) and Insomnia Start of enrollment: 2019 Feb 04
- A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) Start of enrollment: 2022 Sep 30
Publications & Presentations
PubMed
- 1 citationsA digital therapeutic (CT-152) as adjunct to antidepressant medication: A phase 3 randomized controlled trial (the Mirai study).Brian Rothman, Mary Slomkowski, Austin Speier, A John Rush, Madhukar H Trivedi
Journal of Affective Disorders. 2025-11-01 - 1 citationsEffectiveness, Engagement, and Safety of a Digital Therapeutic (CT-155/BI 3972080) for Treating Negative Symptoms in People With Schizophrenia: Protocol for the Phase ...Shaheen E Lakhan, Cornelia Dorner-Ciossek, Olya Besedina, Faith Dickerson, Claudia Hastedt
JMIR Research Protocols. 2025-10-07 - 1 citationsSoftware-Enhanced Drugs™: The third platform reshaping drug development.Shaheen E Lakhan, Paul Wicks
Proceedings of the National Academy of Sciences of the United States of America. 2025-09-30
Press Mentions
Agetech Research Round-up: Brain Health Vital, £38m to Combat Alzheimers, and More…January 14th, 2026
Oral Health a Neglected Stroke Risk Factor?October 27th, 2025
Tear down the Wall Between Neurology and PsychiatryOctober 23rd, 2025
Professional Memberships
- Fellow
- International Association for the Study of Pain - IASPMember
- Member
- Member
Other Languages
- Hebrew, Spanish
External Links
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