ShaktiSinghMD

Gastroenterology • Chandler, AZ

Advanced Endoscopic Interventional

Gastroenterologist

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Office
2971 W. Elliot Rd.
Suite 3
Chandler, AZ 85224
Phone+1 480-733-0500

Fax+1 480-659-8366
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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Gastroenterology, 2002 - 2005
Icahn School of Medicine at Mount Sinai (Beth Israel)Internship, Internal Medicine, 1999 - 2000
State University of New York Downstate Medical Center College of MedicineClass of 1999
St. John's UniversityB.S., Biology, 1992 - 1995

Certifications & Licensure

AZ State Medical License 2016 - 2025
CA State Medical License 2000 - 2025
WY State Medical License 2017 - 2022
American Board of Internal Medicine Gastroenterology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Star Achievement Award for Excellent Patient Service Sutter Gould Medical Foundation, 2010
Commendation in Investigative Scholarship State University of Brooklyn Health Science Center, 1999
1994All American Scholar Collegiate Award St. John's University, 1994
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Publications & Presentations

PubMed

21 citations
Combination treatment of liposomal amphotericin B and isavuconazole is synergistic in treating experimental mucormycosis.
Teclegiorgis Gebremariam, Yiyou Gu, Shakti Singh, Therese M Kitt, Ashraf S. Ibrahim> ;The Journal of Antimicrobial Chemotherapy. 2021 Sep 15
99 citations
Adaptive immunity induces mutualism between commensal eukaryotes.
Kyla S. Ost, Teresa R. O’Meara, W. Zac Stephens, Tyson R. Chiaro, Haoyang Zhou, Jourdan Penman, Rickesha Bell, Jason Catanzaro, Deguang Song, Shakti Singh, Daniel H. C...> ;Nature. 2021 Jul 14
7 citations
An evolutionarily diverged mitochondrial protein controls biofilm growth and virulence in Candida albicans.
Zeinab Mamouei, Shakti Singh, Bernard D. Lemire, Yiyou Gu, Abdullah Alqarihi, Sunna Nabeela, Dongmei Li, Ashraf S. Ibrahim, Priya Uppuluri> ;Plos Biology. 2021 Mar 15
43 citations
Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis.
Sameh S. M. Soliman, Clara Baldin, Yiyou Gu, Shakti Singh, Teclegiorgis Gebremariam, Marc Swidergall, Abdullah Alqarihi, Eman G. Youssef, Sondus Alkhazraji, Antonis Pi...> ;Nature Microbiology. 2021 Jan 18
41 citations
An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris
Kali R. Iyer, Kaddy Camara, Martin Daniel-Ivad, Richard Trilles, Sheila M. Pimentel-Elardo, Jen Fossen, Karen Marchillo, Zhongle Liu, Shakti Singh, José F. Muñoz, Sang...> ;Nature Communications. 2020 Dec 22
2 citations
Editorial: Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies
Shakti Singh, Stephanie K. Yanow, Babita Agrawal> ;Frontiers in Immunology. 2020 Jul 7
13 citations
Monoclonal IgM Antibodies Targeting Candida albicans Hyr1 Provide Cross-Kingdom Protection Against Gram-Negative Bacteria.
Eman G. Youssef, Lina Zhang, Sondus Alkhazraji, Teclegiorgis Gebremariam, Shakti Singh, Nannette Y. Yount, Michael R. Yeaman, Priya Uppuluri, Ashraf S. Ibrahim> ;Frontiers in Immunology. 2020 Feb 18
8 citations
Galactomannan Is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis.
Teclegiorgis Gebremariam, Sondus Alkhazraji, Yiyou Gu, Shakti Singh, Abdullah Alqarihi, Karen Joy Shaw, Ashraf S. Ibrahim> ;Antimicrobial Agents and Chemotherapy. 2019 Dec 20
47 citations
Fosmanogepix (APX001) is effective in the treatment of immunocompromised mice infected with invasive pulmonary scedosporiosis or disseminated fusariosis
Sondus Alkhazraji, Teclegiorgis Gebremariam, Abdullah Alqarihi, Yiyou Gu, Zeinab Mamouei, Shakti Singh, Nathan P. Wiederhold, Karen J Shaw, Ashraf S. Ibrahim> ;Antimicrobial Agents and Chemotherapy. 2020 Feb 21
78 citations
The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection.
Shakti Singh, Priya Uppuluri, Zeinab Mamouei, Abdullah Alqarihi, Hana Elhassan, Samuel Wheeler French, Shawn R. Lockhart, Tom Chiller, John E. Edwards, Ashraf S. Ibrahim> ;Plos Pathogens. 2019 Aug 5
8 citations
Heterologous Immunity between Adenoviruses and Hepatitis C Virus (HCV): Recombinant Adenovirus Vaccine Vectors Containing Antigens from Unrelated Pathogens Induce Cros...
Babita Agrawal, Nancy Gupta, Satish Vedi, Shakti Singh, Wen Li, Saurabh Garg, Jie Li, Rakesh K. Kumar> ;Cells. 2019 May 26
20 citations
NDV-3A vaccination prevents C. albicans colonization of jugular vein catheters in mice
Abdullah Alqarihi, Shakti Singh, John E. Edwards, Ashraf S. Ibrahim, Priya Uppuluri> ;Scientific Reports. 2019 Apr 17
36 citations
Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens.
Zeinab Mamouei, Abdullah Alqarihi, Shakti Singh, Shuying Xu, Michael K. Mansour, Ashraf S. Ibrahim, Priya Uppuluri> ;Msphere. 2018 Oct 31
30 citations
Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based...
Shakti Singh, Eric G. Ramírez-Salazar, Rami Doueiri, Antonio Valentin, Margherita Rosati, Xintao Hu, Brandon F. Keele, Xiaoying Shen, Georgia D. Tomaras, Guido Ferrari...> ;Journal of Virology. 2018 Jul 17
22 citations
Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis.
Priya Uppuluri, Shakti Singh, Abdullah Alqarihi, Clint S. Schmidt, John P. Hennessey, Michael R. Yeaman, Scott G. Filler, John E. Edwards, Ashraf S. Ibrahim> ;Frontiers in Immunology. 2018 Jun 15
7 citations
Unsolved Puzzles Surrounding HCV Immunity: Heterologous Immunity Adds Another Dimension
Babita Agrawal, Shakti Singh, Nancy Gupta, Wen Li, Satish Vedi, Rakesh K. Kumar> ;International Journal of Molecular Sciences. 2017 Jul 27
10 citations
Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines.
Shakti Singh, Satish Vedi, Subodh Kumar Samrat, Wen Li, Rakesh K. Kumar, Babita Agrawal> ;Plos One. 2016 Jan 11
3 citations
Editorial: Influenza Virus Vaccines and Immunotherapies.
Arun Kumar, Shakti Singh> ;Frontiers in Immunology. 2015 Nov 24
6 citations
Immunization with Recombinant Adenoviral Vectors Expressing HCV Core or F Proteins Leads to T Cells with Reduced Effector Molecules Granzyme B and IFN-γ: A Potential N...
Subodh Kumar Samrat, Satish Vedi, Shakti Singh, Wen Li, Rakesh K. Kumar, Babita Agrawal> ;Viral Immunology. 2015 Jul 2
9 citations
Recombinant adenoviral vector expressing HCV NS4 induces protective immune responses in a mouse model of Vaccinia-HCV virus infection: a dose and route conundrum.
Shakti Singh, Satish Vedi, Wen Li, Subodh Kumar Samrat, Rakesh K. Kumar, Babita Agrawal> ;Vaccine. 2014 May 13
55 citations
Transplacental rotavirus IgG interferes with immune response to live oral rotavirus vaccine ORV-116E in Indian infants.
Mohan Babu Appaiahgari, Roger I. Glass, Shakti Singh, Sunita Taneja, Temsunaro Rongsen-Chandola, Nita Bhandari, Sukhdev Mishra, Sudhanshu Vrati> ;Vaccine. 2014 Feb 3
14 citations
Alternate reading frame protein (F protein) of hepatitis C virus: paradoxical effects of activation and apoptosis on human dendritic cells lead to stimulation of T cells.
Subodh Kumar Samrat, Wen Li, Shakti Singh, Rakesh K. Kumar, Babita Agrawal> ;Plos One. 2014 Jan 27
9 citations
Descriptive epidemiology of rotavirus infection in a community in North India.
T. R. Chandola, Sunita Taneja, N. Goyal, S. S. Rathore, Mohan Babu Appaiahgari, A. Mishra, Shakti Singh, Sudhanshu Vrati, Nita Bhandari> ;Epidemiology and Infection. 2013 Oct 1
61 citations
A Dose-Escalation Safety and Immunogenicity Study of Live Attenuated Oral Rotavirus Vaccine 116E in Infants: A Randomized, Double-Blind, Placebo-Controlled Trial
Nita Bhandari, Pooja Sharma, Sunita Taneja, Tivendra Kumar, Temsunaro Rongsen-Chandola, Mohan Babu Appaiahgari, Arpita Mishra, Shakti Singh, Sudhanshu Vrati> ;The Journal of Infectious Diseases. 2009 Aug 1
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Professional Memberships

American College of Gastroenterology - ACG
Member

Hospital Affiliations

Chandler Regional Medical CenterChandler, Arizona