ShaneOttoLebeauMDECNU

Endocrinology • Pittsburgh, PA

Lipid Metabolism, Parathyroid, Pituitary Disorders & Neuroendocrinology, Thyroid

Medical Principal, Clinical Performance and Quality, Cigna Healthcare

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Office
3000 Park Ln
Pittsburgh, PA 15275
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Education & Training

University of Pennsylvania Health SystemFellowship, Endocrinology, Diabetes, and Metabolism, 2003 - 2005
Icahn School of Medicine at Mount Sinai/Mount Sinai HospitalResidency, Internal Medicine, 1999 - 2002
Ohio State University College of MedicineClass of 1999

Certifications & Licensure

PA State Medical License 2003 - 2024
AZ State Medical License 2020 - 2021
NY State Medical License 2001 - 2005
OH State Medical License 1999 - 2000
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011
Top MD Consumers Checkbook
Diabetes Care Recognition Health Care Incentives Improvement Institute

Publications & Presentations

PubMed

2 citations
Comparison of the collection approaches of 2 large thyroid fine-needle aspiration practices reveals differing advantages for cytology and molecular testing adequacy ra...
Michael S. Landau, Thomas M. Pearce, Sally E. Carty, Jenna Wolfe, Linwah Yip, Kelly L. McCoy, Shane O. LeBeau, Mitchell Tublin, N. Paul Ohori> ;Journal of the American Society of Cytopathology. 2019 Sep 1
35 citations
Benign call rate and molecular test result distribution of ThyroSeq v3.
N. Paul Ohori, Michael S. Landau, Sally E. Carty, Linwah Yip, Shane O. LeBeau, Pooja Manroa, Raja R. Seethala, Karen E. Schoedel, Marina N. Nikiforova, Yuri E. Nikiforov> ;Cancer Cytopathology. 2019 Mar 1
39 citations
Correct extent of thyroidectomy is poorly predicted preoperatively by the guidelines of the American Thyroid Association for low and intermediate risk thyroid cancers.
Mashaal Dhir, Kelly L. McCoy, N. Paul Ohori, Cameron D. Adkisson, Shane O. LeBeau, Sally E. Carty, Linwah Yip> ;Surgery. 2018 Jan 1
28 citations
The influence of the noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) resection diagnosis on the false-positive thyroid cytology ra...
N. Paul Ohori, Jenna Wolfe, Sally E. Carty, Linwah Yip, Shane O. LeBeau, Aaron N. Berg, Karen E. Schoedel, Yuri E. Nikiforov, Raja R. Seethala> ;Cancer Cytopathology. 2017 Sep 1
46 citations
Preoperative detection of RAS mutation may guide extent of thyroidectomy.
Snehal G. Patel, Sally E. Carty, Kelly L. McCoy, N. Paul Ohori, Shane O. LeBeau, Raja R. Seethala, Marina N. Nikiforova, Yuri E. Nikiforov, Linwah Yip> ;Surgery. 2017 Jan 1
268 citations
Impact of the Multi-Gene ThyroSeq Next-Generation Sequencing Assay on Cancer Diagnosis in Thyroid Nodules with Atypia of Undetermined Significance/Follicular Lesion of...
Yuri E. Nikiforov, Sally E. Carty, Simon I. Chiosea, Christopher Coyne, Umamaheswar Duvvuri, Robert L. Ferris, William E. Gooding, Shane O. LeBeau, N. Paul Ohori, Raja...> ;Thyroid. 2015 Nov 6
2 citations
Significance of what is not sampled: Characteristics of thyroid nonmicrocarcinomas (>1.0 cm) that were not targeted.
Karen E. Schoedel, Jenna Wolfe, Steven P. Hodak, Shane O. LeBeau, Linwah Yip, Sally E. Carty, Marina N. Nikiforova, Yuri E. Nikiforov, N. Paul Ohori> ;Cancer Cytopathology. 2015 Nov 1
78 citations
Tumor genotype determines phenotype and disease-related outcomes in thyroid cancer: a study of 1510 patients.
Linwah Yip, Marina N. Nikiforova, Jenny Y. Yoo, Kelly L. McCoy, Michael T. Stang, Michaele J. Armstrong, Kristina J. Nicholson, N. Paul Ohori, Christopher J. Coyne, St...> ;Annals of Surgery. 2015 Sep 1
348 citations
Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing...
Yuri E. Nikiforov, Sally E. Carty, Simon I. Chiosea, Christopher J. Coyne, Umamaheswar Duvvuri, Robert L. Ferris, William E. Gooding, Steven P. Hodak, Shane O. LeBeau,...> ;Cancer. 2014 Dec 1
45 citations
Thyroid nodules with KRAS mutations are different from nodules with NRAS and HRAS mutations with regard to cytopathologic and histopathologic outcome characteristics.
Lisa A. Radkay, Simion I. Chiosea, Raja R. Seethala, Steven P. Hodak, Shane O. LeBeau, Linwah Yip, Kelly L. McCoy, Sally E. Carty, Karen E. Schoedel, Marina N. Nikifor...> ;Cancer Cytopathology. 2014 Dec 1
49 citations
A clinical algorithm for fine-needle aspiration molecular testing effectively guides the appropriate extent of initial thyroidectomy.
Linwah Yip, Laura I. Wharry, Michaele J. Armstrong, Ari Silbermann, Kelly L. McCoy, Michael T. Stang, Nobuyuki P. Ohori, Shane O. LeBeau, Christopher J. Coyne, Marina ...> ;Annals of Surgery. 2014 Jul 1
48 citations
Thyroid nodules (≥4 cm): can ultrasound and cytology reliably exclude cancer?
Laura I Wharry, Kelly L McCoy, Michael T Stang, Michaele J Armstrong, Shane O LeBeau, Mitch E Tublin, Biatta Sholosh, Ari Silbermann, N Paul Ohori, Yuri E Nikiforov, S...> ;World Journal of Surgery. 2014 Mar 1
18 citations
Effects of Testosterone and Growth Hormone on the Structural and Mechanical Properties of Bone by Micro-MRI in the Distal Tibia of Men With Hypopituitarism
Mona Al Mukaddam, Chamith S. Rajapakse, Yusuf A. Bhagat, Felix W. Wehrli, Wensheng Guo, Helen Peachey, Shane O. LeBeau, Babette S. Zemel, Christina Wang, Ronald S. Swe...> ;The Journal of Clinical Endocrinology and Metabolism. 2014 Jan 13
18 citations
“Colloid‐Rich” follicular neoplasm/suspicious for follicular neoplasm thyroid fine‐needle aspiration specimens: Cytologic, histologic, and molecular basis for consider...
N. Paul Ohori, Jenna Wolfe, Steven P. Hodak, Shane O. LeBeau, Linwah Yip, Sally E. Carty, Umamaheswar Duvvuri, Karen E. Schoedel, Marina N. Nikiforova, Yuri E. Nikiforov> ;Cancer Cytopathology. 2013 Dec 1
26 citations
Nodule size is an independent predictor of malignancy in mutation-negative nodules with follicular lesion of undetermined significance cytology
Rohtesh S. Mehta, Sally E. Carty, N. Paul Ohori, Steven P. Hodak, Christopher Coyne, Shane O. LeBeau, Mitchell Tublin, Michael T. Stang, Jonas T. Johnson, Kelly L. McC...> ;Surgery. 2013 Oct 1
61 citations
BRAF mutation detection in indeterminate thyroid cytology specimens: underlying cytologic, molecular, and pathologic characteristics of papillary thyroid carcinoma.
N. Paul Ohori, Rashi L. Singhal, Marina N. Nikiforova, Linwah Yip, Karen E. Schoedel, Christopher Coyne, Kelly L. McCoy, Shane O. LeBeau, Steven P. Hodak, Sally E. Car...> ;Cancer Cytopathology. 2013 Apr 1
102 citations
RAS mutations in thyroid FNA specimens are highly predictive of predominantly low-risk follicular-pattern cancers.
Nikhil Gupta, Anil K. Dasyam, Sally E. Carty, Marina N. Nikiforova, N. Paul Ohori, Michaele J. Armstrong, Linwah Yip, Shane O. LeBeau, Kelly L. McCoy, Christopher J. C...> ;The Journal of Clinical Endocrinology and Metabolism. 2013 Mar 28
98 citations
A combined molecular-pathologic score improves risk stratification of thyroid papillary microcarcinoma.
Leo A. Niemeier, Haruko Kuffner Akatsu, Chi Song, Sally E. Carty, Steven P. Hodak, Linwah Yip, Robert L. Ferris, George C. Tseng, Raja R. Seethala, Shane O. LeBeau, Mi...> ;Cancer. 2012 Apr 15
533 citations
Impact of Mutational Testing on the Diagnosis and Management of Patients with Cytologically Indeterminate Thyroid Nodules: A Prospective Analysis of 1056 FNA Samples
Yuri E. Nikiforov, N. Paul Ohori, Steven P. Hodak, Sally E. Carty, Shane O. LeBeau, Robert L. Ferris, Linwah Yip, Raja R. Seethala, Mitchell Tublin, Michael T. Stang, ...> ;The Journal of Clinical Endocrinology and Metabolism. 2011 Aug 31
52 citations
Both BRAF V600E mutation and older age (≥ 65 years) are associated with recurrent papillary thyroid cancer.
Gina M. Howell, Sally E. Carty, Michaele J. Armstrong, Shane O. LeBeau, Steven P. Hodak, Christopher Coyne, Michael T. Stang, Kelly L. McCoy, Marina N. Nikiforova, Yur...> ;Annals of Surgical Oncology. 2011 May 19
6 citations
Imaging Surveillance of Differentiated Thyroid Cancer
Nathan A. Johnson, Shane O. LeBeau, Mitchell Tublin> ;Radiologic Clinics of North America. 2011 May 1
4 citations
Diagnosis and Treatment of Differentiated Thyroid Carcinoma
Amy E. Cox, Shane O. LeBeau> ;Radiologic Clinics of North America. 2011 May 1
3 citations
Multiple paragangliomas in a pregnant patient with a succinate dehydrogenase B mutation.
Sonali Ganguly, Shane O. LeBeau, Kim Pierce, Ramesh K. Ramanathan, Rose Salata> ;Postgraduate Medicine. 2010 Nov 1
82 citations
Evaluation of a thyroid nodule
Steven R. Bomeli, Shane O. LeBeau, Robert L. Ferris> ;Otolaryngologic Clinics of North America. 2010 Apr 1
197 citations
Contribution of molecular testing to thyroid fine-needle aspiration cytology of "follicular lesion of undetermined significance/atypia of undetermined significance"
N. Paul Ohori, Marina N. Nikiforova, Karen E. Schoedel, Shane O. LeBeau, Steven P. Hodak, Raja R. Seethala, Sally E. Carty, Jennifer B. Ogilvie, Linwah Yip, Yuri E. Ni...> ;Cancer Cytopathology. 2010 Feb 25
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