ShannonLeigh(Huggins)Huggins-PuhallaMD

PubMed

• 14 citations
  Cisplatin with veliparib or placebo in metastatic triple-negative breast cancer and BRCA mutation-associated breast cancer (S1416): a randomised, double-blind, placebo...
  Eve Rodler, Priyanka Sharma, William E Barlow, Julie R Gralow, Shannon L Puhalla, Carey K Anders, Lori Goldstein, Debu Tripathy, Ursa A Brown-Glaberman, Thu-Tam Huynh,...> ;The Lancet. Oncology. 2023 Feb 1
• 45 citations
  Atezolizumab With Neoadjuvant Anti-Human Epidermal Growth Factor Receptor 2 Therapy and Chemotherapy in Human Epidermal Growth Factor Receptor 2-Positive Early Breast ...
  Jens Huober, Carlos H Barrios, Naoki Niikura, Michał Jarząb, Yuan-Ching Chang, Shannon L Huggins-Puhalla, José Pedrini, Lyudmila Zhukova, Vilma Graupner, Daniel Eiger,...> ;Journal of Clinical Oncology. 2022 Sep 1
• 5 citations
  A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovari...
  Julia Manzo, Shannon Puhalla, Shalu Pahuja, Fei Ding, Yan Lin, Leonard Appleman, Hussein Tawbi, Ronald Stoller, James J Lee, Brenda Diergaarde, Brian F Kiesel, Jing Yu...> ;Cancer Chemotherapy and Pharmacology. 2022 May 1
• 6 citations
  Clinical-pathologic characteristics and response to neoadjuvant chemotherapy in triple-negative low Ki-67 proliferation (TNLP) breast cancers.
  Pooja Srivastava, Tiannan Wang, Beth Z Clark, Jing Yu, Jeffrey L Fine, Tatiana M Villatoro, Gloria J Carter, Adam M Brufsky, Vikram C Gorantla, Shannon L Huggins-Puhal...> ;NPJ Breast Cancer. 2022 Apr 20
• 14 citations
  Veliparib monotherapy following carboplatin/paclitaxel plus veliparib combination therapy in patients with germline BRCA-associated advanced breast cancer: results of ...
  Hyo S. Han, Banu Arun, Bella Kaufman, Hans Wildiers, Michael Friedlander, J.P. Ayoub, Shannon Puhalla, Bruce A. Bach, Madan Gopal Kundu, N. Khandelwal, D. Feng, S. Bha...> ;Annals of Oncology. 2021 Nov 30
• 7 citations
  Biomarkers of response and resistance to palbociclib plus letrozole in patients with ER+/HER2- breast cancer.
  Mitch Dowsett, Lucy Kilburn, Mothaffar F. Rimawi, C. Kent Osborne, Katherine L. Pogue-Geile, Yuan Liu, Samuel A. Jacobs, Melanie Finnigan, Shannon Puhalla, Andrew Dods...> ;Clinical Cancer Research. 2021 Oct 13
• 10 citations
  Efficacy and safety of first-line veliparib and carboplatin-paclitaxel in patients with HER2- advanced germline BRCA+ breast cancer: Subgroup analysis of a randomised ...
  Banu Arun, Hyo S. Han, Bella Kaufman, Hans Wildiers, Michael Friedlander, Jean Pierre Ayoub, Shannon Puhalla, Katherine M. Bell-McGuinn, Bruce A. Bach, Madan Gopal Kun...> ;European Journal of Cancer. 2021 Jul 6
• 1 citations
  Phase 1 study of safety, pharmacokinetics, and pharmacodynamics of tivantinib in combination with bevacizumab in adult patients with advanced solid tumors
  William F. Maguire, John C. Schmitz, Jonas Scemama, Ken Czambel, Yan Lin, Anthony Green, Shaoyu Wu, Huang Lin, Shannon Puhalla, John C. Rhee, Ronald G. Stoller, Hussei...> ;Cancer Chemotherapy and Pharmacology. 2021 Jun 23
• 9 citations
  Relevance of Platinum-free Interval and BRCA Reversion Mutations for Veliparib Monotherapy after Progression on Carboplatin/Paclitaxel for gBRCA Advanced Breast Cancer...
  Shannon Puhalla, Véronique Diéras, Banu Arun, Bella Kaufman, Hans Wildiers, Hyo S. Han, Jean-Pierre M. Ayoub, Vered Stearns, Yuan Yuan, Teresa Helsten, Bridget Riley-G...> ;Clinical Cancer Research. 2021 Sep 15
• 4 citations
  Prognostic factors and survival of patients undergoing surgical intervention for breast cancer bone metastases.
  Margaret L. Hankins, Clair N. Smith, Beverly L Hersh, Tanya Heim, Sean W. Dooley, Adrian V. Lee, Steffi Oesterreich, Peter C. Lucas, Shannon Puhalla, Kurt R. Weiss, Re...> ;Journal of Bone Oncology. 2021 May 3
• 8 citations
  Abemaciclib in Combination With Endocrine Therapy for Patients With Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Phase 1b Study.
  Sara M Tolaney, Muralidhar Beeram, J Thaddeus Beck, Alison Conlin, E Claire Dees, Shannon L Puhalla, Brent N Rexer, Howard A Burris, Komal Jhaveri, Teresa Helsten, Car...> ;Frontiers in Oncology. 2021 Jan 1
• 11 citations
  Safety and efficacy of veliparib plus carboplatin/paclitaxel in patients with HER2-negative metastatic or locally advanced breast cancer: subgroup analyses by germline...
  Jean-Pierre Ayoub, Hans Wildiers, Michael Friedlander, Banu K Arun, Hyo S Han, Shannon Puhalla, Yaroslav Shparyk, Erik H Jakobsen, Meijing Wu, Bruce A Bach, Dai Feng, ...> ;Therapeutic Advances in Medical Oncology. 2021 Jan 1
• 170 citations
  Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer (BROCADE3): a randomised, double-blind, placebo-controlled, phase 3 trial
  Véronique Diéras, Hyo Sook Han, Bella Kaufman, Hans Wildiers, Michael Friedlander, Jean Pierre Ayoub, Shannon Puhalla, Igor Bondarenko, Mario Campone, Erik Jakobsen, M...> ;The Lancet. Oncology. 2020 Oct 1
• 112 citations
  ANG1005, a brain penetrating peptide-drug conjugate, shows activity in patients with breast cancer with leptomeningeal carcinomatosis and recurrent brain metastases.
  Priya Kumthekar, Shou-Ching Tang, Andrew Brenner, Santosh Kesari, David Piccioni, Carey K. Anders, Jose Carrillo, Pavani Chalasani, Peter Kabos, Shannon Puhalla, Kathe...> ;Clinical Cancer Research. 2020 Jun 15
• 15 citations
  Pre- and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022
  Rachel A. Freedman, Rebecca Gelman, Nathalie Y. R. Agar, Sandro Santagata, Elizabeth C. Randall, Begoña Gimenez-Cassina Lopez, Roisin M. Connolly, Ian F. Dunn, Catheri...> ;Clinical Breast Cancer. 2020 Apr 1
• 8 citations
  TBCRC 002: a phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormon...
  Christos Vaklavas, Brian S. Roberts, Katherine E. Varley, Nan Lin, Minetta C. Liu, Hope S. Rugo, Shannon Puhalla, Rita Nanda, Anna Maria Storniolo, Lisa A. Carey, Mans...> ;Breast Cancer Research. 2020 Feb 18
• 28 citations
  Phase 1 study of veliparib (ABT-888), a poly (ADP-ribose) polymerase inhibitor, with carboplatin and paclitaxel in advanced solid malignancies
  Leonard Joseph Appleman, Jan H. Beumer, Yixing Jiang, Yan Lin, Fei Ding, Shannon Puhalla, Leigh Swartz, Taofeek K. Owonikoko, R. Donald Harvey, Ronald G. Stoller, Dani...> ;Cancer Chemotherapy and Pharmacology. 2019 Dec 1
• 3 citations
  Health-related quality of life in patients receiving first-line eribulin mesylate with or without trastuzumab for locally recurrent or metastatic breast cancer.
  Lee S. Schwartzberg, Kristi McIntyre, Sharon Wilks, Shannon Puhalla, Joyce O'Shaughnessy, Erhan Berrak, Yaohua He, Linda T. Vahdat> ;BMC Cancer. 2019 Jun 13
• 64 citations
  Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets.
  Damir Varešlija, Nolan Priedigkeit, Ailis Fagan, Siobhan Purcell, Nicola Cosgrove, Philip J. O’Halloran, Elspeth Ward, Sinead Cocchiglia, Ryan J. Hartmaier, Carlos A. ...> ;Journal of the National Cancer Institute. 2019 Apr 1
• 220 citations
  TBCRC 022: A phase II trial of neratinib and capecitabine for patients with human epidermal growth factor receptor 2-positive breast cancer and brain metastases
  Rachel A. Freedman, Rebecca Gelman, Carey K. Anders, Michelle E. Melisko, Heather A. Parsons, Anne Cropp, Kelly Silvestri, Christine M Cotter, Kathryn P. Componeschi, ...> ;Journal of Clinical Oncology. 2019 Mar 12
• 19 citations
  Targeted mutation detection in breast cancer using MammaSeq
  Nicholas G. Smith, Rekha Gyanchandani, Osama Shiraz Shah, Grzegorz T. Gurda, Peter C. Lucas, Ryan J. Hartmaier, Adam Brufsky, Shannon Puhalla, Amir Bahreini, Karthik K...> ;Breast Cancer Research. 2019 Feb 8
• 46 citations
  Metaplastic breast carcinoma: a clinical-pathologic study of 97 cases with subset analysis of response to neoadjuvant chemotherapy.
  Min Han, Arsalan Salamat, Li Zhu, Huina Zhang, Beth Z. Clark, David J. Dabbs, Gloria Carter, Adam Brufsky, Rachel C. Jankowitz, Shannon Puhalla, Ronald Johnson, Atilla...> ;Modern Pathology. 2019 Feb 5
• 114 citations
  Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor–Positive Early Breast Cancer: PALLET Trial
  Stephen R. D. Johnston, Shannon Puhalla, Duncan Wheatley, Alistair Ring, Peter A. Barry, Chris Holcombe, Jean Francois Boileau, Louise Provencher, André Robidoux, Moth...> ;Journal of Clinical Oncology. 2019 Jan 20
• 14 citations
  Whole genome amplification of cell-free DNA enables detection of circulating tumor DNA mutations from fingerstick capillary blood
  Rekha Gyanchandani, Erik Leeming Kvam, Ryan Charles Heller, Erin Finehout, Nicholas G. Smith, Karthik Kota, John Richard Nelson, Weston Blaine Griffin, Shannon Puhalla...> ;Scientific Reports. 2018 Nov 23
• 42 citations
  Low Estrogen Receptor (ER)-Positive Breast Cancer and Neoadjuvant Systemic Chemotherapy: Is Response Similar to Typical ER-Positive or ER-Negative Disease?
  Alessandra Landmann, Daniel J. Farrugia, Li Zhu, Emilia J Diego, Ronald Johnson, Atilla Soran, David J. Dabbs, Beth Z. Clark, Shannon Puhalla, Rachel C. Jankowitz, Ada...> ;American Journal of Clinical Pathology. 2018 May 31
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