SharonRachelGrossmanMDPhD

PubMed

• An integrated map of genetic variation from 1,092 human genomes.
  1000 Genomes Project Consortium, Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, Kang HM, Marth GT, McVean GA> ;Nature.
• 267 citations
  Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics
  Ekta Khurana, Yao Fu, Vincenza Colonna, Xinmeng Jasmine Mu, Hyun Min Kang, Tuuli Lappalainen, Andrea Sboner, Lucas Lochovsky, Jieming Chen, Arif Harmanci, Jishnu Das, ...> ;Science. 2013 Oct 4
• Response to "Letter to the Editor Regarding Vaping." Seven Reasons E-cigarettes Must Be "Downright Prohibited" Now!
  Sharon Galper Grossman> ;Rambam Maimonides Medical Journal. 2019 Oct 29
• 425 citations
  Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations.
  Charles P. Fulco, Joseph Nasser, Thouis R. Jones, Glen Munson, Drew T. Bergman, Vidya Subramanian, Sharon R. Grossman, Rockwell Anyoha, Benjamin R. Doughty, Tejal A. P...> ;Nature Genetics. 2019 Jul 3
• 38 citations
  Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk.
  Yakir A. Reshef, Hilary K. Finucane, David R. Kelley, Alexander Gusev, Dylan Kotliar, Jacob C. Ulirsch, Farhad Hormozdiari, Joseph Nasser, Luke J. O’Connor, Bryce van ...> ;Nature Genetics. 2018 Sep 3
• 48 citations
  Positional specificity of different transcription factor classes within enhancers
  Sharon R. Grossman, Jesse M. Engreitz, John P. Ray, Tung T. Nguyen, Nir Hacohen, Eric S. Lander> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Jul 24
• 103 citations
  Systematic dissection of genomic features determining transcription factor binding and enhancer function
  Sharon R. Grossman, Xiaolan Zhang, Li Wang, Jesse M. Engreitz, Alexandre Melnikov, Peter Rogov, Ryan Tewhey, Alina Isakova, Bart Deplancke, Bradley E. Bernstein, Tarje...> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Feb 14
• 368 citations
  Systematic mapping of functional enhancer-promoter connections with CRISPR interference
  Charles P. Fulco, Mathias Munschauer, Rockwell Anyoha, Glen Munson, Sharon R. Grossman, Elizabeth M. Perez, Michael Kane, Brian Cleary, Eric S. Lander, Jesse M. Engreitz> ;Science. 2016 Sep 29
• 1 citations
  The Angelina Jolie Effect in Jewish Law: Prophylactic Mastectomy and Oophorectomy in BRCA Carriers.
  Sharon Galper Grossman> ;Rambam Maimonides Medical Journal. 2015 Oct 26
• 352 citations
  RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites.
  Jesse M. Engreitz, Klara Sirokman, Patrick McDonel, Alexander A. Shishkin, Christine Surka, Pamela Russell, Sharon R. Grossman, Amy Y. M. Chow, Mitchell Guttman, Eric ...> ;Cell. 2014 Sep 25
• Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences.
  Colonna V, Ayub Q, Chen Y, Pagani L, Luisi P, Pybus M, Garrison E, Xue Y, Tyler-Smith C, 1000 Genomes Project Consortium, Abecasis GR, Auton A, Brooks LD, DePristo MA,...> ;Genome biology. 2014-06-30
• Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel.
  Delaneau O, Marchini J, 1000 Genomes Project Consortium, 1000 Genomes Project Consortium> ;Nature communications. 2014-06-13
• 376 citations
  Detecting natural selection in genomic data.
  Joseph J. Vitti, Sharon R. Grossman, Pardis C. Sabeti> ;Annual Review of Genetics. 2013 Nov 25
• 252 citations
  Identifying Recent Adaptations in Large-Scale Genomic Data
  Shamai A. Grossman, Kristian G. Andersen, Ilya Shlyakhter, Shervin Tabrizi, Sarah M. Winnicki, Angela Yen, Daniel J. Park, Dustin Griesemer, Elinor K. Karlsson, Sunny ...> ;Cell. 2013 Feb 14
• The 1000 Genomes Project: data management and community access.
  Clarke L, Zheng-Bradley X, Smith R, Kulesha E, Xiao C, Toneva I, Vaughan B, Preuss D, Leinonen R, Shumway M, Sherry S, Flicek P, 1000 Genomes Project Consortium> ;Nature methods. 2012-04-27
• 68 citations
  Genome-wide scans provide evidence for positive selection of genes implicated in Lassa fever
  Kristian G. Andersen, Ilya Shylakhter, Shervin Tabrizi, Sharon R. Grossman, Christian T. Happi, Pardis C. Sabeti> ;Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 2012 Mar 19
• 724 citations
  Detecting Novel Associations in Large Data Sets
  David N. Reshef, Yakir A. Reshef, Hilary K. Finucane, Sharon R. Grossman, Gilean McVean, Peter J. Turnbaugh, Eric S. Lander, Michael Mitzenmacher, Pardis C. Sabeti> ;Science. 2011 Dec 16
• The functional spectrum of low-frequency coding variation.
  Marth GT, Yu F, Indap AR, Garimella K, Gravel S, Leong WF, Tyler-Smith C, Bainbridge M, Blackwell T, Zheng-Bradley X, Chen Y, Challis D, Clarke L, Ball EV, Cibulskis K...> ;Genome biology. 2011-09-14
• Demographic history and rare allele sharing among human populations.
  Gravel S, Henn BM, Gutenkunst RN, Indap AR, Marth GT, Clark AG, Yu F, Gibbs RA, 1000 Genomes Project, Bustamante CD> ;Proceedings of the National Academy of Sciences of the United States of America. 2011-07-05
• Variation in genome-wide mutation rates within and between human families.
  Conrad DF, Keebler JE, DePristo MA, Lindsay SJ, Zhang Y, Casals F, Idaghdour Y, Hartl CL, Torroja C, Garimella KV, Zilversmit M, Cartwright R, Rouleau GA, Daly M, Ston...> ;Nature genetics. 2011-06-12
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