ShaunCoughlinMD

PubMed

• 9 citations
  Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models.
  Fumin Fu, Michael Pietropaolo, Lei Cui, Shilpa Pandit, Weiyan Li, Oleg Tarnavski, Suraj S Shetty, Jing Liu, Jennifer M Lussier, Yutaka Murakami, Prabhjit K Grewal, Gal...> ;Plos One. 2022 Jan 7
• 3 citations
  Thoracic Surgeon Impressions of the Impact of the COVID-19 Pandemic on Lung Cancer Care-Lessons from the First Wave in Canada.
  Roy A Hilzenrat, Shaun Deen, John Yee, Kyle Grant, Ahmad S Ashrafi, Shaun R. Coughlin, Anna L. McGuire> ;Current Oncology. 2021 Feb 18
• 67 citations
  Microglial Gi-dependent dynamics regulate brain network hyperexcitability.
  Mario Merlini, Victoria A. Rafalski, Keran Ma, Keunyoung Kim, Eric A. Bushong, Pamela E. Rios Coronado, Zhaoqi Yan, Andrew S. Mendiola, Elif G. Sozmen, Jae K. Ryu, Mat...> ;Nature Neuroscience. 2021 Jan 1
• 43 citations
  Protease-Activated Receptor-2 Regulates Neuro-Epidermal Communication in Atopic Dermatitis
  Timo Buhl, Akihiko Ikoma, Cordula Kempkes, Ferda Cevikbas, Mathias Sulk, Joerg Buddenkotte, Tasuku Akiyama, Debbie Crumrine, Eric Camerer, Earl Carstens, Michael P. Sc...> ;Frontiers in Immunology. 2020 Aug 12
• 53 citations
  Designing a Green Fluorogenic Protease Reporter by Flipping a Beta Strand of GFP for Imaging Apoptosis in Animals.
  Qiang Zhang, Antonino Schepis, Hai Huang, Junjiao Yang, Wen Ma, Joaquim Torra, Shao-Qing Zhang, Lina Yang, Haifan Wu, Santi Nonell, Zhiqiang Dong, Thomas B. Kornberg, ...> ;Journal of the American Chemical Society. 2019 Mar 1
• 184 citations
  A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish
  Roland S. Wu, Ian Lam, Hilary Clay, Daniel N. Duong, Rahul C. Deo, Shaun R. Coughlin> ;Developmental Cell. 2018 Jul 2
• 10 citations
  Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia.
  Antonino Schepis, Adrian Barker, Yoga Srinivasan, Eaman Balouch, Yaowu Zheng, Ian Lam, Hilary Clay, Chung-Der Hsiao, Shaun R. Coughlin> ;The Journal of Cell Biology. 2018 Jan 4
• 11 citations
  A rapid fluorogenic GPCR-β-arrestin interaction assay.
  Qiang Zhang, Yaowu Zheng, Shaun R. Coughlin, Xiaokun Shu> ;Protein Science. 2018 Feb 23
• 6 citations
  Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent.
  Lauren Kate Ely, Marco Lolicato, Tovo David, Kate L Lowe, Yun Cheol Kim, Dharmaraj Samuel, Paul Bessette, Jorge L. Garcia, Thomas Mikita, Daniel L. Minor, Shaun R. Cou...> ;Structure. 2018 Feb 6
• 16 citations
  Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia
  Xuan Jiang, Whitney Wooderchak-Donahue, Jamie McDonald, Prajakta Ghatpande, Mai Baalbaki, Melissa Sandoval, Daniel O. Hart, Hilary Clay, Shaun R. Coughlin, Giorgio Lag...> ;Science Signaling. 2018 Jan 16
• 35 citations
  Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter.
  Qiang Zhang, Hai Huang, Luqing Zhang, Roland Wu, Chan-I Chung, Shao-Qing Zhang, Joaquim Torra, Antonino Schepis, Shaun R Coughlin, Thomas B Kornberg, Xiaokun Shu> ;Molecular Cell. 2018 Jan 18
• First Search for Nontensorial Gravitational Waves from Known Pulsars.
  Abbott, B. P.,Abbott, R.,Abbott, T. D.,Acernese, F.,Ackley, K.,Adams, C.,Adams, T.,Addesso, P.,Adhikari, R. X.,Adya, V. B.,Affeldt, C.,Afrough, M.,Agarwal, B.,Agathos,...> ;Phys. Rev. Lett.. 2018 Feb 06
• 654 citations
  The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors
  Emma Lefrançais, Guadalupe Ortiz-Muñoz, Axelle Caudrillier, Beñat Mallavia, Fengchun Liu, David M. Sayah, Emily E. Thornton, Mark B. Headley, Tovo David, Shaun R. Coug...> ;Nature. 2017 Apr 6
• 36 citations
  Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development.
  Hilary Clay, Lisa D. Wilsbacher, Stephen J. Wilson, Daniel N. Duong, Maayan McDonald, Ian Lam, Kitae Eric Park, Jerold Chun, Shaun R. Coughlin> ;Developmental Biology. 2016 Oct 1
• 49 citations
  Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic ...
  Salome L. Gazit, Boubacar Mariko, Patrice Therond, Benoit Decouture, Yuquan Xiong, Ludovic Couty, Philippe Bonnin, Véronique Baudrie, Sylvain M. Le Gall, Blandine Dizi...> ;Circulation Research. 2016 Aug 31
• 40 citations
  Factor XIa–specific IgG and a reversal agent to probe factor XI function in thrombosis and hemostasis
  Tovo David, Yun Cheol Kim, Lauren Kate Ely, Isaac Rondon, Huilan Gao, Peter J. O'Brien, Michael W. Bolt, Anthony J. Coyle, Jorge L. Garcia, Eric A. Flounders, Thomas M...> ;Science Translational Medicine. 2016 Aug 24
• 31 citations
  Rational Design of a GFP-Based Fluorogenic Caspase Reporter for Imaging Apoptosis In Vivo
  Tsz-Leung To, Antonino Schepis, Rubén Ruiz-González, Qiang Zhang, Dan Yu, Zhiqiang Dong, Shaun R. Coughlin, Xiaokun Shu> ;Cell Chemical Biology. 2016 Jul 21
• 87 citations
  A mutation in the atrial-specific myosin light chain gene ( MYL4 ) causes familial atrial fibrillation
  Nathan Orr, Rima Arnaout, Lorne J. Gula, Danna A. Spears, Peter Leong-Sit, Qiuju Li, Wadea Tarhuni, Sven Reischauer, Vijay S. Chauhan, Matthew Borkovich, Shaheen Uppal...> ;Nature Communications. 2016 Apr 12
• 52 citations
  Identifying and quantifying two ligand-binding sites while imaging native human membrane receptors by AFM
  Moritz Pfreundschuh, David Alsteens, Ralph Wieneke, Cheng Zhang, Shaun R. Coughlin, Robert Tampé, Brian K. Kobilka, Daniel J. Müller> ;Nature Communications. 2015 Nov 12
• 73 citations
  An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish
  Jun Zou, Diana Tran, Mai Baalbaki, Ling Fung Tang, Annie Poon, Angelo Pelonero, Erron W. Titus, Christiana Yuan, Chenxu Shi, Shruthi Patchava, Elizabeth Halper, Jasmin...> ;Elife. 2015 Oct 16
• 30 citations
  Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography.
  Michael J. Page, André Luiz Lourenço, Tovo David, Aaron M. LeBeau, Fiore Cattaruzza, Helena Carla Castro, Henry F. VanBrocklin, Shaun R. Coughlin, Charles S. Craik> ;Nature Communications. 2015 Oct 1
• 75 citations
  Imaging G protein–coupled receptors while quantifying their ligand-binding free-energy landscape
  David Alsteens, Moritz Pfreundschuh, Cheng Zhang, Patrizia M. Spoerri, Shaun R. Coughlin, Brian K. Kobilka, Daniel J. Müller> ;Nature Methods. 2015 Sep 1
• 66 citations
  Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense
  Joni M. Prasad, Oleg V. Gorkun, Harini Raghu, Sherry Thornton, Eric S. Mullins, Joseph S. Palumbo, Ya-Ping Ko, Magnus Höök, Tovo David, Shaun R. Coughlin, Jay L. Degen...> ;Blood. 2015 Oct 22
• 6 citations
  Analysis of cardiomyocyte development using immunofluorescence in embryonic mouse heart.
  Lisa D. Wilsbacher, Shaun R. Coughlin> ;Journal of Visualized Experiments. 2015 Mar 26
• 47 citations
  Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion.
  Miles Berger, David W. Scheel, Hector Macias, Takeshi Miyatsuka, Hail Kim, Phuong Hoang, Greg M. Ku, Gerard Honig, Angela Liou, Yunshuo Tang, Jean B. Regard, Panid Sha...> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Mar 3
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Lectures

• Basic Cardiovascular Sciences (BCVS) 2013 Scientific Sessions 
  American Heart Association, Las Vegas, Nevada - 7/22/2013