SheilaArvikarMD

Rheumatology • Boston, MA

Rheumatoid Arthritis & Related

Instructor in Medicine, Harvard Medical School/Massachusetts General Hospital

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Office
Massachusetts General Hospital
Yawkey 2c, 55 Fruit Street
Boston, MA 02114
Phone+1 617-726-7938
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Summary

Dr. Sheila Arvikar is a rheumatologist in Boston, MA and is affiliated with Massachusetts General Hospital. She received her medical degree from UMass Chan Medical School and has been in practice 11 years. Her research and clinical practice focuses om rheumatoid arthritis & Lyme arthritis.

Education & Training

Massachusetts General HospitalFellowship, Rheumatology, 2009 - 2011
Massachusetts General HospitalResidency, Internal Medicine, 2006 - 2009
University of Massachusetts Medical SchoolClass of 2006

Certifications & Licensure

MA State Medical License 2009 - 2024
NH State Medical License 2021 - 2023
RI State Medical License 2021 - 2022
American Board of Internal Medicine Rheumatology

Awards, Honors, & Recognition

Scientist Development Award Rheumatology Research Foundation, 2015
Young Investigator Bone and Joint Initiative, 2013
Don Riggin Research Award Arthritis Foundation, 2012
Fellow American College of Rheumatology
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Publications & Presentations

PubMed

1 citations
Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis.
Korawit Kanjana, Klemen Strle, Robert B Lochhead, Annalisa Pianta, Laura M Mateyka, Qi Wang, Sheila L Arvikar, David E Kling, Cameron A Deangelo, Lucy Curham, Alan G B...> ;The Journal of Clinical Investigation. 2023 Sep 1
2 citations
Cell-Mediated Cytotoxicity in Lyme Arthritis.
David Ordóñez, Robert B Lochhead, Klemen Strle, Annalisa Pianta, Sheila Arvikar, Ildiko Van Rhijn, Anat Stemmer-Rachamimov, Allen C Steere> ;Arthritis & Rheumatology. 2023 May 1
4 citations
Lyme Arthritis.
Sheila L Arvikar, Allen C Steere> ;Infectious Disease Clinics of North America. 2022 Sep 1
30 citations
Lyme arthritis: linking infection, inflammation and autoimmunity.
Robert B. Lochhead, Klemen Strle, Sheila L. Arvikar, Janis J. Weis, Allen C. Steere> ;Nature Reviews. Rheumatology. 2021 Jul 5
16 citations
Identification of Novel, Immunogenic HLA-DR-Presented Prevotella copri Peptides in Patients with Rheumatoid Arthritis
Annalisa Pianta, Geena Chiumento, Kristina Ramsden, Qi Wang, Klemen Strle, Sheila L. Arvikar, Catherine E. Costello, Allen C. Steere> ;Arthritis & Rheumatology. 2021 May 27
9 citations
Periodontal inflammation and distinct inflammatory profiles in saliva and gingival crevicular fluid compared with serum and joints in rheumatoid arthritis patients
Sheila L. Arvikar, Hatice Hasturk, Klemen Strle, Danielle Stephens, Marcy B. Bolster, Deborah S. Collier, Alpdogan Kantarci, Allen C. Steere> ;Journal of Periodontology. 2021 Oct 1
An 80-Year-Old Man With Fevers, Altered Mental Status, and Joint Effusions.
Naomi Serling-Boyd, Zachary S. Wallace, Jana Jarolimova, Sheila L. Arvikar, Eli M. Miloslavsky> ;Arthritis Care & Research. 2020 Mar 1
3 citations
Case 22-2019: A 65-Year-Old Woman With Weakness, Dark Urine, and Dysphagia
Mason W. Freeman, Amanda C. Guidon, Sheila L. Arvikar, Robert H. Goldstein, Nathan F. Clement, Ajay K. Singh> ;The New England Journal of Medicine. 2019 Jul 17
1 citations
Case 17-2019: A 44-Year-Old Man with Joint Pain, Weight Loss, and Chest Pain.
Sheila L. Arvikar, Sara R. Schoenfeld, Andrew S. Fox, Varsha K. Tanguturi, Lena D. Stuart> ;The New England Journal of Medicine. 2019 May 29
22 citations
Interferon-gamma production in Lyme arthritis synovial tissue promotes differentiation of fibroblast-like synoviocytes into immune effector cells.
Robert B. Lochhead, David Ordoñez, Sheila L. Arvikar, John M. Aversa, Luke S. Oh, Benton E. Heyworth, Ruslan I. Sadreyev, Allen C. Steere, Klemen Strle> ;Cellular Microbiology. 2019 Feb 1
21 citations
Robust interferon signature and suppressed tissue repair gene expression in synovial tissue from patients with postinfectious, Borrelia burgdorferi-induced Lyme arthri...
Robert B. Lochhead, Sheila L. Arvikar, John M. Aversa, Ruslan I. Sadreyev, Klemen Strle, Allen C. Steere> ;Cellular Microbiology. 2019 Feb 1
121 citations
Two rheumatoid arthritis–specific autoantigens correlate microbial immunity with autoimmune responses in joints
Annalisa Pianta, Sheila L. Arvikar, Klemen Strle, Elise E. Drouin, Qi Wang, Catherine E. Costello, Allen C. Steere> ;The Journal of Clinical Investigation. 2017 Aug 1
219 citations
Evidence of the Immune Relevance of Prevotella copri, a Gut Microbe, in Patients With Rheumatoid Arthritis.
Annalisa Pianta, Sheila L. Arvikar, Klemen Strle, Elise E. Drouin, Qi Wang, Catherine E. Costello, Allen C. Steere> ;Arthritis & Rheumatology. 2017 May 1
Granulomatous skin involvement in a patient with an unusual NOD2 mutation.
Ifedayo O. Kuye, Morayo Adisa, Rosalynn M. Nazarian, Sheila L. Arvikar, Gideon P. Smith> ;The Australasian Journal of Dermatology. 2017 May 1
46 citations
T-Helper 17 Cell Cytokine Responses in Lyme Disease Correlate With Borrelia burgdorferi Antibodies During Early Infection and With Autoantibodies Late in the Illness i...
Klemen Strle, Katherine B. Sulka, Annalisa Pianta, Jameson T. Crowley, Sheila L. Arvikar, Anthony Anselmo, Ruslan I. Sadreyev, Allen C. Steere> ;Clinical Infectious Diseases. 2017 Apr 1
28 citations
MicroRNA Expression Shows Inflammatory Dysregulation and Tumor-Like Proliferative Responses in Joints of Patients With Postinfectious Lyme Arthritis.
Robert B. Lochhead, Klemen Strle, Nancy D. Kim, Minna J. Kohler, Sheila L. Arvikar, John M. Aversa, Allen C. Steere> ;Arthritis & Rheumatology. 2017 May 1
37 citations
Autoimmune Arthritides, Rheumatoid Arthritis, Psoriatic Arthritis, or Peripheral Spondyloarthritis Following Lyme Disease
Sheila L. Arvikar, Jameson T. Crowley, Katherine B. Sulka, Allen C. Steere> ;Arthritis & Rheumatology. 2017 Jan 1
Letter to the Editor: Reply to Tuttle.
Arvikar Sl, Steere Ac> ;Arthritis & Rheumatology. 2016 Nov 11
39 citations
Matrix metalloproteinase-10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis
Jameson T. Crowley, Klemen Strle, Elise E. Drouin, Annalisa Pianta, Sheila L. Arvikar, Qi Wang, Catherine E. Costello, Allen C. Steere> ;Journal of Autoimmunity. 2016 May 1
43 citations
Annexin A2 is a target of autoimmune T and B cell responses associated with synovial fibroblast proliferation in patients with antibiotic-refractory Lyme arthritis.
Annalisa Pianta, Elise E. Drouin, Jameson T. Crowley, Sheila L. Arvikar, Klemen Strle, Catherine E. Costello, Allen C. Steere> ;Clinical Immunology. 2015 Oct 1
2 citations
CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 22-2015. A 20-Year-Old Man with Sore Throat, Fever, Myalgias, and a Pericardial Effusion.
Daniel P. Hunt, Jonathan A. Scheske, David M. Dudzinski, Sheila L. Arvikar> ;The New England Journal of Medicine. 2015 Jul 15
3 citations
Editorial Commentary: What Constitutes Appropriate Treatment of Post-Lyme Disease Symptoms and Other Pain and Fatigue Syndromes?
Allen C. Steere, Sheila L. Arvikar> ;Clinical Infectious Diseases. 2015 Jun 15
124 citations
Diagnosis and treatment of Lyme arthritis.
Sheila L. Arvikar, Allen C. Steere> ;Infectious Disease Clinics of North America. 2015 Jun 1
54 citations
Clinical correlations with Porphyromonas gingivalis antibody responses in patients with early rheumatoid arthritis
Sheila L. Arvikar, Deborah S. Collier, Mark Fisher, Sebastian Unizony, George L. Cohen, Gail McHugh, Toshihisa Kawai, Klemen Strle, Allen C. Steere> ;Arthritis Research & Therapy. 2013 Sep 9
217 citations
Tocilizumab for the treatment of large-vessel vasculitis (giant cell arteritis, Takayasu arteritis) and polymyalgia rheumatica.
Sebastian Unizony, L. Arias-Urdaneta, Eli M. Miloslavsky, Sheila L. Arvikar, Arezou Khosroshahi, Brian J. Keroack, James R. Stone, John H. Stone> ;Arthritis Care & Research. 2012 Nov 1
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Press Mentions

Reconsider Post Lyme Disease Treatment Options, Study SaysFebruary 1st, 2017

Professional Memberships

American College of Rheumatology - ACR
Member

Hospital Affiliations

Massachusetts General HospitalBoston, Massachusetts