ShellyLuMD

PubMed

• S-Adenosylmethionine Negatively Regulates the Mitochondrial Respiratory Chain Repressor MCJ in the Liver.
  Barbier-Torres, L., Chhimwal, J., Kim, S., Ramani, K., Robinson, A., Yang, H., Van Eyk, J., Seki, E., Mato, J., Liangpunsakul, S., Lu, S.> ;International Journal of Biological Sciences. 2024 Jan 1
• Sumoylation of methionine adenosyltransferase alpha 1 promotes mitochondrial dysfunction in alcohol-associated liver disease.
  Floris, A., Chandla, S., Lim, Y., Barbier-Torres, L., Seth, K., Khangholi, A., Li, T., Robison, A., Murray, B., Lee, S., Murali, R., Tomasi, M., Matsuda, M., Lu, S.> ;Hepatology. 2023 Dec 15
• Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis.
  Fan, W., Cao, D., Yang, B., Wang, J., Li, X., Kitka, D., Li, T., You, S., Shiao, S., Gangi, A., Posadas, E., Di Vizio, D., Tomasi, M., Seki, E., Mato, J., Yang, H., Lu...> ;Journal of Hepatology. 2024 Mar 1
• CSNK2A1-mediated MAX phosphorylation upregulates HMGB1 and IL-6 expression in cholangiocarcinoma progression.
  Bing Yang, Jing Zhang, Jiaohong Wang, Wei Fan, Lucía Barbier-Torres, Xi Yang, Monica Anne R Justo, Ting Liu, Yongheng Chen, Justin Steggerda, Komal Ramani, Shelly C Lu...> ;Hepatology Communications. 2023 Jul 1
• 21 citations
  Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment.
  Zhijun Wang, So Yeon Kim, Wei Tu, Jieun Kim, Alexander Xu, Yoon Mee Yang, Michitaka Matsuda, Lien Reolizo, Takashi Tsuchiya, Sandrine Billet, Alexandra Gangi, Mazen No...> ;Cell Metabolism. 2023 Jul 11
• 1 citations
  Hyperphosphorylation of hepatic proteome characterizes nonalcoholic fatty liver disease in S-adenosylmethionine deficiency.
  Aaron E Robinson, Aleksandra Binek, Komal Ramani, Niveda Sundararaman, Lucía Barbier-Torres, Ben Murray, Vidya Venkatraman, Simion Kreimer, Angela Mc Ardle, Mazen Nour...> ;Iscience. 2023 Feb 17
• 4 citations
  One Carbon Metabolism and-Adenosylmethionine in Non-Alcoholic Fatty Liver Disease Pathogenesis and Subtypes.
  David Fernández-Ramos, Fernando Lopitz-Otsoa, Oscar Millet, Cristina Alonso, Shelly C Lu, José M Mato> ;Livers. 2022 Dec 1
• 5 citations
  An NMR-Based Model to Investigate the Metabolic Phenoreversion of COVID-19 Patients throughout a Longitudinal Study.
  Rubén Gil-Redondo, Ricardo Conde, Maider Bizkarguenaga, Chiara Bruzzone, Ana Laín, Beatriz González-Valle, Milagros Iriberri, Carlos Ramos-Acosta, Eduardo Anguita, Jua...> ;Metabolites. 2022 Dec 1
• 1 citations
  Deletion of adipocyte prohibitin 1 exacerbates high-fat diet-induced steatosis but not liver inflammation and fibrosis.
  Xiaolin Wang, Seung-Jin Kim, Yukun Guan, Richard Parker, Robim M Rodrigues, Dechun Feng, Shelly C Lu, Bin Gao> ;Hepatology Communications. 2022 Dec 1
• 6 citations
  TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis.
  David Matye, Sumedha Gunewardena, Jianglei Chen, Huaiwen Wang, Yifeng Wang, Mohammad Nazmul Hasan, Lijie Gu, Yung Dai Clayton, Yanhong Du, Cheng Chen, Jacob E Friedman...> ;Nature Communications. 2022 Sep 28
• In Memoriam Vinay Sundaram (1978-2022).
  Rajiv Jalan, Shelly Lu, Alexander Kuo> ;Journal of Hepatology. 2022 Sep 1
• 13 citations
  HCC EV ECG score: An extracellular vesicle-based protein assay for detection of early-stage hepatocellular carcinoma.
  Na Sun, Ceng Zhang, Yi-Te Lee, Benjamin V Tran, Jing Wang, Hyoyong Kim, Junseok Lee, Ryan Y Zhang, Jasmine J Wang, Junhui Hu, Zhicheng Zhang, Manaf S Alsudaney, Kuan-C...> ;Hepatology. 2023 Mar 1
• 11 citations
  Nonalcoholic fatty liver disease prevalence and severity in Asian Americans from the national health and nutrition examination surveys 2017-2018.
  Emily Truong, Yee Hui Yeo, Galen Cook-Wiens, Mark Muthiah, Ju Dong Yang, Vinay Sundaram, Devon Chang, Tsuyoshi Todo, Irene K Kim, Shelly C Lu, Veronica Wendy Setiawan,...> ;Hepatology Communications. 2022 Sep 1
• 23 citations
  Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles.
  Ibon Martínez-Arranz, Chiara Bruzzone, Mazen Noureddin, Ruben Gil-Redondo, Itziar Mincholé, Maider Bizkarguenaga, Enara Arretxe, Marta Iruarrizaga-Lejarreta, David Fer...> ;Hepatology. 2022 Oct 1
• 15 citations
  Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease.
  Lucía Barbier-Torres, Ben Murray, Jin Won Yang, Jiaohong Wang, Michitaka Matsuda, Aaron Robinson, Aleksandra Binek, Wei Fan, David Fernández-Ramos, Fernando Lopitz-Ots...> ;Nature Communications. 2022 Jan 28
• Magnetic resonance imaging for characterization of hepatocellular carcinoma metabolism.
  Lixia Wang, Ju Dong Yang, Charles C Yoo, Keane K Y Lai, Jonathan Braun, Dermot P B McGovern, Yibin Xie, Stephen J Pandol, Shelly C Lu, Debiao Li> ;Frontiers in Physiology. 2022 Jan 1
• 34 citations
  The Mortality and Overall Survival Trends of Primary Liver Cancer in the United States.
  Yi-Te Lee, Jasmine J. Wang, Michael Luu, Mazen Noureddin, Kambiz Kosari, Vatche G. Agopian, Nicole E. Rich, Shelly C. Lu, Hsian-Rong Tseng, Nicholas N. Nissen, Amit G....> ;Journal of the National Cancer Institute. 2021 Nov 2
• 43 citations
  Incidence of Pancreatic Cancer by Age and Sex in the US, 2000-2018.
  Srinivas Gaddam, Yazan Abboud, Janice Oh, Jamil S. Samaan, Nicholas N. Nissen, Shelly C. Lu, Simon K. Lo> ;JAMA. 2021 Oct 24
• 14 citations
  S-Adenosylmethionine Inhibits La Ribonucleoprotein Domain Family Member 1 in Murine Liver and Human Liver Cancer Cells.
  Komal Ramani, Aaron E Robinson, Joshua E. Berlind, Wei Fan, Aushinie Abeynayake, Aleksandra Binek, Lucía Barbier-Torres, Mazen Noureddin, Nicholas N. Nissen, Zehra Yil...> ;Hepatology. 2021 Aug 27
• 5 citations
  Deregulated 14-3-3ζ and methionine adenosyltransferase α1 interplay promotes liver cancer tumorigenesis in mice and humans.
  Liqing Lu, Jing Zhang, Wei Fan, Yuan Li, Jiaohong Wang, Tony W.H. Li, Lucía Barbier-Torres, José M. Mato, Ting Liu, Ekihiro Seki, Michitaka Matsuda, Maria Lauda Tomasi...> ;Oncogene. 2021 Aug 4
• 23 citations
  Modeling alcohol-associated liver disease in a human Liver-Chip.
  Janna Nawroth, Debora B. Petropolis, Dimitris V. Manatakis, Tengku Ibrahim Maulana, Gabriel Burchett, Katharina Schlünder, Anke Witt, Abhishek Shukla, Konstantia Kodel...> ;Cell Reports. 2021 Jul 20
• 17 citations
  A molecular signature for the metabolic syndrome by urine metabolomics.
  Chiara Bruzzone, Rubén Gil-Redondo, Marisa Seco, Rocío Barragán, Laura de la Cruz, Claire Cannet, Hartmut Schäfer, Fang Fang, Tammo Diercks, Maider Bizkarguenaga, Beat...> ;Cardiovascular Diabetology. 2021 Jun 15
• 9 citations
  Anti-miR-518d-5p Overcomes Liver Tumor Cell Death Resistance Through Mitochondrial Activity
  Pablo Fernández-Tussy, Rubén Rodríguez-Agudo, David Fernández-Ramos, Lucía Barbier-Torres, Imanol Zubiete-Franco, Sergio López de Davalillo, Elisa Herraez, Naroa Goiko...> ;Cell Death & Disease. 2021 May 28
• 9 citations
  Comparison of Surgical Resection and Systemic Treatment for Hepatocellular Carcinoma with Vascular Invasion: National Cancer Database Analysis
  Rajalakshmi Govalan, Marie Lauzon, Michael Luu, Joseph C. Ahn, Kambiz Kosari, Tsuyoshi Todo, Irene K. Kim, Mazen Noureddin, Alexander Kuo, Ayoub S. Walid, Vinay Sundar...> ;Liver Cancer. 2021 Apr 23
• 6 citations
  Transarterial radioembolization versus systemic treatment for hepatocellular carcinoma with macrovascular invasion: Analysis of the US National Cancer Database
  Joseph C. Ahn, Marie Lauzon, Michael Luu, Marc L. Friedman, Kambiz Kosari, Nicholas N. Nissen, Shelly C. Lu, Lewis R. Roberts, Amit G. Singal, Ju Dong Yang> ;Journal of Nuclear Medicine. 2021 Apr 9
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Journal Articles

• NASH Leading Cause of Liver Transplant in Women: Updated Analysis of Indications for Liver Transplant and Ethnic and Gender Variances  
  Tsuyoshi Todo, Walid S Ayoub, Naim Alkhouri, Nicholas N Nissen, Vinay Sundaram, Shelly C Lu, Mazen Noureddin, Aarshi Vipani, Tram Tran, Andrew S Klein, Nature
• Liver receptor homolog 1 and transmethylation fluxes in nonalcoholic steatohepatitis  
  Lu SC, Hepatology, 1/1/2016
• Sex and racial/ethnic differences in the association of obesity with risk of hepatocellular carcinoma  
  Setiawan VW, Lim U, Lipworth L, Lu SC, Shepherd J, Ernst T, Henderson BE, Le Marchand L, Clin Gastroenterology Hepatol, 1/1/2016
• Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis  
  Zubiete-Franco I, García-Rodríguez JL, Martínez-Uña M, Matínez-Lopez N, Woodhoo A, Gutiérrez-De JV, Beraza N, Lage-Medina S, Andrade F, Fernandez ML, Aldámiz-Echevarrí..., J Hepatol, 1/1/2016
• Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes  
  Murray B, Antonyuk SV, Marina A, Lu SC, Mato JM, Hasnain S, Rojas AL, PNAS, 1/1/2016
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  Yang HP, Liu T, Wang J, Li TWH, Fan W, Peng H, Krishnan A, Gores GJ, Mato JM, and Lu SC, Hepatology, 1/1/2016
• Prohibitin 1 regulates the H19-Igf2 axis and proliferation in hepatocytes  
  Ramani K, Mavila N, Ko KS, Mato JM, Lu SC, J. Biol. Chem., 1/1/2016
• Nonalcoholic fatty liver disease: update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine  
  Noureddin M, Mato JM, and Lu SC, Exp. Biol Med, 1/1/2015
• S-adenosylmethionine and methylthioadenosine inhibit beta catenin signaling by multiple mechanisms in liver and colon cancer  
  Li TWH, Peng H, Yang HP, Kuriniawidjaja S, Panthaki P, Zheng Y, Mato JM, and Lu SC, Mol. Pharmacol., 1/1/2015
• Activation of a novel c-Myc-miR27-Prohibitin 1 circuitry in cholestatic liver injury inhibits GSH synthesis in mice  
  Yang HP, Li TWH, Zhou Y, Peng H, Liu T, Zandi E, Martínez-Chantar ML, Mato JM, and Lu SC, Antioxidant & Redox Signaling, 1/1/2015
• Coffee intake, chronic liver diseases and hepatocellular carcinoma: the Multiethnic Cohort  
  Setiawan VW, Wilkens LR, Lu SC, Hernandez BY, Le Marchand L, Henderson BE, Gastroenterology, 1/1/2015
• TRAIL-producing NK cells contribute to fibrogenesis in the context of GNMT deficiency  
  Fernández-Álvarez S, Gutiérrez-de Juan V, Zubiete-Franco I, Lahoz A, Parés A, Luka Z, Wagner C, Lu SC, Mato JM, Martínez-Chantar ML, and Beraza N, Lab Invest., 1/1/2015
• S-adenosylmethionine regulates very-low density lipoprotein assembly, features and plasma metabolism in nonalcoholic fatty liver disease  
  Martínez-Uña M, Varela M, Mestre D, Fernández-Ares L, Fresnedo O, Fernandez-Ramos D, Gutiérrez-de Juan V, Martin-Guerrero I, García-Orad A, Luka Z, Wagner C, Lu SC, Ga..., J Hepatol., 1/1/2015
• HDAC4 promotes cholestatic liver injury in the absence of prohibitin-1  
  Barbier-Torres L, Beraza N, Fernández-Tussy P, Lopitz-Otsoa F, Fernández-Ramos D, Zubiete-Franco I, Varela-Rey M, Delgado TC, Gutiérrez V, Anguita J, Pares A, Banales ..., Hepatology, 1/1/2015
• Methionine adenosyltransferase a2 positively regulates B-cell CLL/lymphoma 2 expression in a sumoylation-dependent manner  
  Tomasi ML, Ryoo M, Tomasi I, Giordano P, Mato JM, and Lu SC, Oncotarget, 1/1/2015
• Nutritional status and infection risk in cirrhosis: examining both ends of the spectrum  
  Sundaram V, Kaung A, Rajaram A, Lu SC, Tran TT, Klein AS, Jalan R, Charlton MR, Jeon CY, Alimentary Pharmacology & Therapeutics, 1/1/2015
• Systems biology for hepatologists  
  Mato JM, Martínez-Chantar ML, and Lu SC, Hepatology, 1/1/2014
• Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice  
  Tomasi ML, Ryoo M, Yang HP, Iglesia Ara A, Ko K, and Lu SC, Free Radical Biology & Medicine, 1/1/2014
• Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveal candidate markers for liver toxicity  
  Rodríguez-Suárez E, González E, Hughes C, Conde-Vancells J, Rudella A, Royo F, Palomo L, Elortza F, Lu SC, Mato JM, Vissers JPC, and Falcón-Pérez JM, J. Proteomics, 1/1/2014
• Diabetes and racial/ethnic differences in hepatocellular carcinoma risk: the multiethnic cohort  
  Setiawan VW, Hernandez B, Lu SC, Stram DO, Wilkens LR, Marchand LL, Henderson BE, J Nat Cancer Inst., 1/1/2014
• S-adenosylmethionine metabolism and liver disease  
  Mato JM, Martínez-Chantar ML, and Lu SC, Annals Hepatology, 1/1/2013
• Glutathione synthesis  
  Lu SC, BBA-Gen, 1/1/2013
• Alcohol, DNA methylation and cancer  
  Varela-Rey M, Woodhoo A, Martínez-Chantar ML, Mato JM, and Lu SC, Alcohol Res, 1/1/2013
• MiRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma  
  Yang HP, Cho ME, Li TWH, Peng H, Ko KS, Mato JM, and Lu SC, J. Clin. Invest., 1/1/2013
• MAT2B-GIT1 interplay activates MEK1/ERK 1 and 2 to induce growth in human liver and colon cancer  
  Peng H, Dara L, Li TWH, Zheng Y, Yang HP, Tomasi ML, Tomasi I, Giordano P, Mato JM, and Lu SC, Hepatology, 1/1/2013
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Books/Book Chapters

• Liver Metabolism and Fatty Liver Disease 
  Chapter: Chapter 6: Oxidative Stress and Disease: Methionine adenosyltransferase genes in liver health and disease 
  Ramani K, Lu SCEditors: Oren Tirosh.Taylor & Francis Group / CRC Press2014
• Amino Acids in Human Nutrition and Health 
  Chapter: Methionine metabolism 
  Mato JM, Martínez-Chantar ML, Lu SCEditors: D’Mello F.CABI, Oxfordshire, UK2011
• Textbook of Gastroenterology 
  Chapter: Cystic diseases of the liver and biliary tree 
  Suh JW, Chang AJ, Lu SCEditors: Yamada T.JB Lippincott, Philadelphia, PAEdition 5th,2009
• Atlas of Gastroenterology 
  Chapter: Cystic diseases of the liver and biliary tree 
  Chang AJ, Suh JW, Lu SCEditors: Yamada T.JB Lippincott, Philadelphia, PAEdition 4th,2009
• Nutrient-Gene Interactions in Cancer 
  Chapter: S-adenosylmethionine and methionine adenosyltransferase genes 
  Mato JM, Martínez-Chantar ML, Lu SCEditors: Choi SW, Friso S.CRC Press LLC, Boca Raton, FLEdition 1st,2006
• Liver Diseases: Biochemical Mechanisms and New Therapeutic Insights 
  Chapter: Methionine adenosyltransferase and S-adenosylmethionine in liver health and disease 
  Lu SC, Mato JMEditors: Shakir A, Friedman SL, Mann D.M/s Sc Pub, Inc., Chicago, ILEdition 1st,2006
• Alcohol, Tobacco and Cancer 
  Chapter: Role of S-adenosyl-L-methionine in alcohol-associated liver cancer 
  Lu SC, Mato JMEditors: Cho CH, Purohit V.Karger AG, Basel, SwitzerlandEdition 1st,2006
• Encyclopedia of Dietary Supplements 
  Chapter: S-adenosylmethionine 
  Mato JM, Lu SCEditors: Coates PM, Blackman MR, Levine M, Moss J, White JD.Marcel Dekker, New York, NYEdition 1st,2005
• Textbook of Gastroenterology 
  Chapter: Cystic diseases of the biliary tree 
  Lu SC, Debian KEditors: Yamada T.JB Lippincott, Philadelphia, PAEdition 4th,2003
• Atlas of Gastroenterology 
  Chapter: Cystic diseases of the biliary tree 
  Lu SC, Debian KEditors: Yamada T.JB Lippincott, Philadelphia, PAEdition 3rrd,2003
• FALK Symposium 113: Cytokines and Cell Homeostasis in the Gastrointestinal Tract 
  Chapter: Glutathione homeostasis in liver regeneration 
  Lu SCEditors: Andus T, Rogler G, Schlottmann K, Frick E, Adler G, Zeitz M, Schmiegel W, Schölmerich J.Kluwer Academic, Dordrecht, NetherlandsEdition 4th,2000
• Kelley's Textbook of Internal Medicine 
  Chapter: Drug-induced hepatic injury 
  Lu SC, Maldonado LEditors: Yamada T.JB Lippincott, Philadelphia, PAEdition 3rd,1996
• Biothiols 
  Chapter: Sinusoidal efflux of hepatic GSH: significance, physiology and regulation 
  Kaplowitz N, Oohktens M, Lu SCEditors: Packer L, Cadenas E.Kluwer Academic, Lancaster, United KingdomEdition 2nd,1995
• Hepatic anion transport and bile secretion: physiology and pathophysiology 
  Chapter: The regulation of hepatic glutathione 
  Fernandez-Checa J, Lu SC, Ookhtens M, DeLeve L, Runnegar M, Yoshida H, Saiki H, Kannan R, Garcia-Ruiz C, Kuhlenkamp JF, Kaplowitz NEditors: Tavoloni N, Berk PD.Raven Press, New York, NYEdition 2nd,1993
• Atlas of Gastroenterology 
  Chapter: Diseases of the biliary tract 
  Lu SC, Kaplowitz N, Hamlin AEditors: Yamada T.JB Lippincott, Philadelphia, PAEdition 1st,1992
• Liver and Biliary Diseases 
  Chapter: Cystic diseases and strictures 
  Lu SCEditors: Kaplowitz N.Williams & Wilkins, Baltimore, MAEdition 9th,1992
• Methionine Metabolism: Molecular Mechanism and Clinical Implications 
  Chapter: Regulation of hepatic GSH synthesis and efflux 
  Kaplowitz N, Lu SC, Ookhtens M, Fernandez-Checa J, Garcia-Ruiz C, Saiki HEditors: Mato J, et al.Edition 3rd,1992
• Gastrointestinal Emergencies 
  Chapter: Acetaminophen toxicity 
  Lu SC, Kaplowitz NEditors: Taylor MB, Gollan JL, Peppercorn MA, Steer ML, Wolfe MM.Williams & Wilkins, Baltimore, MAEdition 1st,1991
• Textbook of Gastroenterology 
  Chapter: Diseases of the biliary tract 
  Lu SC, Kaplowitz NEditors: Yamada T.JB Lippincott, Philadelphia, PAEdition 1st,1991
• Current Hepatology 
  Chapter: Drug-induced hepatotoxicity 
  Lu SC, Kaplowitz NEditors: Gitnick G.Year Book Medical, Chicago, ILEdition 9th,1989
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Abstracts/Posters

• Prohibitin-1 regulates cellular proliferation by controlling the H19-Igf2 axis in the liver
  Ramani K, Mavila N, Lu SC, Hepatology, 1/1/2016
• Prohibitin 1 represses c-Myc-driven E-box gene expression and acts as a tumor suppressor in liver cancers in mice and humans
  Fan W, Yang HP, Wang J, Li TWH, Alagappan A, Mato JM, Lu SC, Hepatology, 1/1/2016
• Metabolomic classification of murine and human nonalcoholic fatty liver disease
  Alonso C, Lavin JL, Iruarrizaga-Lejarreta M, Fernández-Ramos D, van-Liempd S, delaCruz-Villar L, Navasa N, Martínez-Arranz I, Aurrekoetxea I, Buqué X, Varela M, Falcón..., Hepatology, 1/1/2016
• S-Adenosylmethionine treatment corrects deregulated lipid metabolic pathways and prevents progression of non-alcoholic steatohepatitis in methionine adenosyltransferas...
  Fernandez D, Alonso C, van Liempd S, Varela M, Navasa N, Martinez-Arranz I, Aspichueta P, Aransay AM, Anguita J, Falcon-Perez JM, Martinez-Chantar ML, Lu SC, Mato JM, Hepatology, 1/1/2015
• Yang HP, Liu T, Wang J, Li TWH, Mato JM, Lu SC, Hepatology, 1/1/2015
• Subtyping nonalcoholic steatohepatitis for the development of effective treatments
  Martinez-Arranz I, Alonso C, Fernandez D, Mayo R, Varela M, Noureddin M, Martinez-Chantar ML, Lu SC, Castro A, Mato JM, Hepatology, 1/1/2015
• Polyamine and methionine adenosyltransferase 2A crosstalk in human colon cancer
  Tomasi ML, Ryoo M, Skay A, Tomasi I, Giordano P, Mato JM, Lu SC, Gastroenterology, 1/1/2013
• Role of sumoylation in alcoholic liver disease
  Tomasi ML, Ryoo M, Lu SC, Hepatology, 1/1/2013
• Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice
  Tomasi ML, Ryoo M, Lu SC, Hepatology, 1/1/2013
• Ubiquitin-conjugating enzyme 9-methionine adenosyltransferase 2A-Bcl2 axis regulates apoptosis in liver and colon cancer cells
  Tomasi ML, Skay A, Tomasi I, Giordano P, Lu SC, Gastroenterology, 1/1/2012
• Involvement of miRNAs in the regulation of methionine adenosyltransferase 1A expression and tumorigencity in hepatocellular carcinoma
  Yang H, Cho M, Ko K, Li T, Peng H, Mato JM, Lu SC, Gastroenterology, 1/1/2012
• Methionine Adenosyltransferase 2B interacts with G-protein-coupled receptor kinase-interacting protein 1 to activate ERK and induce growth
  Peng H, Dara L, Li TW, Mato JM, Lu SC, Hepatology, 1/1/2012
• Sumoylation of nuclear factor erythroid 2-related factor 2 and MafG protein is essential for glutamate-cysteine ligase catalystic subunit expression in hepatic stellat...
  Ramani K, Tomasi ML, Yang H, Lu SC, Hepatology, 1/1/2012
• Dysregulation of phospho-receptor tyrosine kinase protein levels and microRNAs in methionine adenosyltransferase 1A knockout mice
  Tomasi ML, Ryoo M, Mato JM, Lu SC, Hepatology, 1/1/2012
• The flow from phosphatidylethanolamine to phos-phatidylcholine regulates hepatic lipid homeostasis
  Martínez-Uña M, Varela-Rey M, Fernandez-Ares L, Beraza N, Buqué X, Aurrekoetxea I, Lu SC, Martinez-Chantar ML, Aspichueta P, Mato JM, Hepatology, 1/1/2012
• Obesity Dependent Metabolic signatures associated with nonalcoholic fatty liver disease progression
  Barr J, Caballeria J, Martinez Arranz, I, Dominguez-Diez A, Alonso C, Muntane J, Perez-Cormenzana M, Garcia-Monzon C, Mayo R, Martin-Duce, A, Romero-Gomez M, Lo locono..., Hepatology, 1/1/2011
• S-Adenosylmethionine regulates ubiquitin conjugating enzyme 9 expression and sumoylation:Molecular mechanism and implication in hepatocarcinogenesis
  Tomasi ML, Ramani K, Li TW, Xu J, Mato JM, Lu SC, Hepatology, 1/1/2011
• S-adenosylmethionine regulates ubiquitin-conjugating enzyme 9 protein level and sumoylation
  Tomasi ML, Ramani K, Li TW, Xu J, Mato JM, Lu SC, Hepatology, 1/1/2010
• Expression of glutathione synthetic enzymes during hepatic stellate cell activation and differentiation
  Ramani K, Yang H, Tomasi ML, Ko K, Lu SC, Hepatology, 1/1/2010
• Forced expression of methionine adenosyltransferase 1A (MAT1A) in human hepatoma cells suppresses in vivo tumorigenicity by reducing proliferation and angiogenesis whi...
  Li J, Ramani K, Sun Z, Zee C, Grant EG, Yang H, Xia M, Oh P, Ko K, Mato JM, Lu SC, Hepatology, 1/1/2009
• Proliferative role of LKB1 in the development of hepatocellular varcinoma associated to nonalcohlic steatohepatitis
  Martinez N, Varela-Rey M, Fernandez D, Vasquez M, Embade N, Woodhoo A, Espinosa-Hevia L, Parada LA, Rodriguez MS, Lu SC, Hepatology, 1/1/2009
• S-Adenosylmethionine stablizes dual-specificity MAPK phosphatase protein (DUSP1) by inhibiting protesomal activity: Implication in the pathogenesis and chemoprevention...
  Tomasi ML, Ramani K, Iglesias-Ara A, Li TWH, Bardag-Gorce F, Feo F, Pascale RM, Mato JM, Lu SC, Hepatology, 1/1/2009
• Serum metabolic profiling reveals novel biomarkers associated with liver injury
  Barr J, Alonso C. Suero R, Castro A, Gonzalez E, Conde-Vancells J, Lu SC, Mato JM, Falcon-Perez JM, Hepatology, 1/1/2009
• S-adenosylmethionine regulates apurinic/apyrimidinic endonuclease 1 expression and contributes to increased genomic instability in livers of methionine adenosyltransfe...
  Tomasi ML, Iglesias-Ara A, Feo F, and Lu SC, Gastroenterology, 1/1/2008
• Rountree CB, Ding W, and Lu SC, Gastroenterology, 1/1/2008
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