SidharthJainMD

PubMed

• Deconvolution of immune cell composition and biological age of hepatocellular carcinoma using DNA methylation.
  Sidharth S Jain, Megan E McNamara, Rency S Varghese, Habtom W Ressom> ;Methods. 2023 Oct 1
• 1 citations
  Circulating cell-free methylated DNA reveals tissue-specific, cellular damage from radiation treatment.
  Megan E McNamara, Netanel Loyfer, Amber J Kiliti, Marcel O Schmidt, Sapir Shabi-Porat, Sidharth S Jain, Sarah Martinez Roth, A Patrick McDeed 4th, Nesreen Shahrour, El...> ;JCI Insight. 2023 Jul 24
• Cell-type Deconvolution and Age Estimation Using DNA Methylation Reveals NK Cell Deficiency in the Hepatocellular Carcinoma Microenvironment.
  Sidharth S Jain, Megan E Barefoot, Rency S Varghese, Habtom W Ressom> ;Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 2022 Dec 1
• 4 citations
  RNASeq profiling of COVID19-infected patients identified an EIF2AK2 inhibitor as a potent SARS-CoV-2 antiviral.
  Sidharth Jain, Samantha Rego, Steven Park, Yiran Liu, Simone Parn, Kush Savsani, David S Perlin, Sivanesan Dakshanamurthy> ;Clinical and Translational Medicine. 2022 Nov 1
• 48 citations
  Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.
  Takahiro Ito, Michael J. Young, Ruitong Li, Sidharth S. Jain, Andreas Wernitznig, John M. Krill-Burger, Christopher T. Lemke, Davide Monducci, Diego J. Rodriguez, Lian...> ;Nature Genetics. 2021 Dec 2
• 5 citations
  Integrative Analysis of DNA Methylation and microRNA Expression Reveals Mechanisms of Racial Heterogeneity in Hepatocellular Carcinoma.
  Rency S. Varghese, Megan E. Barefoot, Sidharth Jain, Yifan Chen, Yunxi Zhang, Amber Alley, Alexander Kroemer, Mahlet G. Tadesse, Deepak Kumar, Zaki A. Sherif, Habtom W...> ;Frontiers in Genetics. 2021 Sep 7
• 33 citations
  Molecular basis for substrate recruitment to the PRMT5 methylosome.
  Kathleen M. Mulvaney, Christa Blomquist, Nischal Acharya, Ruitong Li, Matthew J. Ranaghan, Meghan O’Keefe, Diego J. Rodriguez, Michael J. Young, Devishi Kesar, Debjani...> ;Molecular Cell. 2021 Sep 2
• 6 citations
  Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanism.
  Martine Policard, Sidharth Jain, Samantha Rego, Sivanesan Dakshanamurthy> ;Virus Research. 2021 Aug 1
• 13 citations
  Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanism.
  Martine Policard, Sidharth Jain, Samantha Rego, Sivanesan Dakshanamurthy> ;Biorxiv. 2021 Mar 22
• 5 citations
  Low Dose Chronic Angiotensin II Induces Selective Senescence of Kidney Endothelial Cells.
  Irfan Khan, Marcel O Schmidt, Bhaskar Kallakury, Sidharth Jain, Shaunt Mehdikhani, Moshe Levi, Margarida Mendonca, William Welch, Anna T Riegel, Christopher S Wilcox, ...> ;Frontiers in Cell and Developmental Biology. 2021 Jan 1
• 21 citations
  GEMINI: a variational Bayesian approach to identify genetic interactions from combinatorial CRISPR screens
  Mahdi Zamanighomi, Sidharth S. Jain, Takahiro Ito, Debjani Pal, Timothy Daley, William R. Sellers> ;Genome Biology. 2019 Jul 12
• 36 citations
  TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3
  Matthew Murphy, Sujash S. Chatterjee, Sidharth Jain, Manpreet S. Katari, Ramanuj DasGupta> ;Scientific Reports. 2016 Jun 23
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