SidneyNelsonIIIMD

PubMed

• 2 citations
  Should nonselective nonsteroidal anti-inflammatory drugs be avoided following dermatological surgery? A critically appraised topic with a proposed approach to postoper...
  T. Watson Brown, Sidney D. Nelson, T. Nelson> ;Clinical and Experimental Dermatology. 2020 Jan 1
• 4 citations
  Altered secretion patterns and cell wall organization caused by loss of PodB function in the filamentous fungus Aspergillus nidulans.
  Karthik Boppidi, Liliane Fraga Costa Ribeiro, Sirasa Iambamrung, Sidney M. Nelson, Yan Wang, Michelle Momany, Elizabeth A. Richardson, Stephen Lincoln, Ranjan Srivasta...> ;Scientific Reports. 2018 Jul 30
• 4 citations
  A fast and simple method to estimate relative, hyphal tensile-strength of filamentous fungi used to assess the effect of autophagy.
  Daniela Quintanilla, Cynthia Chelius, Sirasa Iambamrung, Sidney M. Nelson, Donnel Thomas, Krist V. Gernaey, Mark R. Marten> ;Biotechnology and Bioengineering. 2018 Mar 1
• 18 citations
  Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer.
  Michael Kyriakides, Léa Maitre, Brendan D. Stamper, Isaac Mohar, Terrance J. Kavanagh, John R. Foster, Ian D. Wilson, Elaine Holmes, Sidney D. Nelson, Muireann Coen> ;Archives of Toxicology. 2016 Jan 9
• 6 citations
  p53 Contributes to Differentiating Gene Expression following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo
  Brendan D. Stamper, Michael L. Garcia, Duy Q. Nguyen, Richard P. Beyer, Theo K. Bammler, Frederico M. Farin, Terrance J. Kavanagh, Sidney D. Nelson> ;Gene Regulation and Systems Biology. 2015 Jun 1
• 31 citations
  Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor–Dependent Hepatotoxicity: Induction of CYP3A4 Enhances the Cytotoxicity of Lapatinib in HepaRG...
  Klarissa D. Hardy, Michelle D. Wahlin, Ioannis Papageorgiou, Jashvant D. Unadkat, Allan E. Rettie, Sidney D. Nelson> ;Drug Metabolism and Disposition. 2014 Jan 1
• 37 citations
  Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6.
  Isaac Mohar, Brendan D. Stamper, Peter M. Rademacher, Charles L. White, Sidney D. Nelson, Terrance J. Kavanagh> ;Redox Biology. 2014 Jan 1
• 35 citations
  Cross-linking mass spectrometry and mutagenesis confirm the functional importance of surface interactions between CYP3A4 and holo/apo cytochrome b(5).
  Chunsheng Zhao, Qiuxia Gao, Arthur G. Roberts, Scott A. Shaffer, Catalin E. Doneanu, Song Xue, David R. Goodlett, Sidney D. Nelson, William M. Atkins> ;Biochemistry. 2012 Nov 27
• 17 citations
  Characterization of rat liver proteins adducted by reactive metabolites of menthofuran.
  S. Cyrus Khojasteh, Dylan P. Hartley, Kevin A. Ford, Hirdesh Uppal, Shimako Oishi, Sidney D. Nelson> ;Chemical Research in Toxicology. 2012 Nov 19
• 5 citations
  Comparative NMR-based metabonomic investigation of the metabolic phenotype associated with tienilic acid and tienilic acid isomer.
  Muireann Coen, Peter M. Rademacher, Wei Zou, Michael A. Scott, Patricia E. Ganey, Robert A. Roth, Sidney D. Nelson> ;Chemical Research in Toxicology. 2012 Nov 5
• 11 citations
  Covalent Modification and Time-Dependent Inhibition of Human CYP2E1 by the Meta Isomer of Acetaminophen
  John Harrelson, Brendan D. Stamper, John D. Chapman, David R. Goodlett, Sidney D. Nelson> ;Drug Metabolism and Disposition. 2012 Aug 1
• 34 citations
  Interaction of lapatinib with cytochrome P450 3A5.
  Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho, Sidney D. Nelson> ;Drug Metabolism and Disposition. 2012 Jul 1
• 71 citations
  An Inducible Cytochrome P450 3A4-Dependent Vitamin D Catabolic Pathway
  Zhican Wang, Yvonne S. Lin, Xi Emily Zheng, Tauri Senn, Takanori Hashizume, Michele Scian, Leslie J. Dickmann, Sidney D. Nelson, Thomas A. Baillie, Mary F. Hebert, Dav...> ;Molecular Pharmacology. 2012 Apr 1
• 10 citations
  Protein tyrosine nitration of mitochondrial carbamoyl phosphate synthetase 1 and its functional consequences.
  Hideo Takakusa, Isaac Mohar, Terrance J. Kavanagh, Edward J. Kelly, Rüdiger Kaspera, Sidney D. Nelson> ;Biochemical and Biophysical Research Communications. 2012 Mar 30
• 31 citations
  Differential Oxidation of Two Thiophene-Containing Regioisomers to Reactive Metabolites by Cytochrome P450 2C9
  Peter M. Rademacher, Caleb M. Woods, Qingbiao Huang, Grazyna D. Szklarz, Sidney D. Nelson> ;Chemical Research in Toxicology. 2012 Mar 14
• 59 citations
  The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4.
  Arthur G. Roberts, Jing Yang, James R. Halpert, Sidney D. Nelson, Kenneth T. Thummel, William M. Atkins> ;Biochemistry. 2011 Dec 20
• 37 citations
  Metabolic Intermediate Complex Formation of Human Cytochrome P450 3A4 by Lapatinib
  Hideo Takakusa, Michelle D. Wahlin, Chunsheng Zhao, Kelsey L. Hanson, Lee Sun New, Eric Chun Yong Chan, Sidney D. Nelson> ;Drug Metabolism and Disposition. 2011 Jun 1
• 27 citations
  Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting.
  Brendan D. Stamper, Isaac Mohar, Terrance J. Kavanagh, Sidney D. Nelson> ;Chemical Research in Toxicology. 2011 Apr 18
• 299 citations
  Managing the challenge of chemically reactive metabolites in drug development
  B. Kevin Park, Alan R. Boobis, Stephen E. Clarke, Christopher E. Goldring, David Jones, J. Gerry Kenna, Craig Lambert, Hugh Laverty, Dean J. Naisbitt, Sidney D. Nelson...> ;Nature Reviews. Drug Discovery. 2011 Apr 1
• 41 citations
  Rearrangement reactions catalyzed by cytochrome P450s
  Paul R. Ortiz de Montellano, Sidney D. Nelson> ;Archives of Biochemistry and Biophysics. 2011 Mar 1
• 24 citations
  Metabolism and toxicity of menthofuran in rat liver slices and in rats
  S. Cyrus Khojasteh, Shimako Oishi, Sidney D. Nelson> ;Chemical Research in Toxicology. 2010 Nov 15
• 83 citations
  Mechanism-Based Inactivation of Cytochrome P450 3A4 by Lapatinib
  Woon Chien Teng, Jing Wen Oh, Lee Sun New, Michelle D. Wahlin, Sidney D. Nelson, Han Kiat Ho, Eric Chun Yong Chan> ;Molecular Pharmacology. 2010 Oct 1
• 25 citations
  Differential regulation of mitogen-activated protein kinase pathways by acetaminophen and its nonhepatotoxic regioisomer 3′-hydroxyacetanilide in TAMH cells
  Brendan D. Stamper, Theo K. Bammler, Richard P. Beyer, Frederico M. Farin, Sidney D. Nelson> ;Toxicological Sciences. 2010 Jul 1
• 32 citations
  Mutagenic activation of tris(2,3-dibromopropyl)phosphate: the role of microsomal oxidative metabolism.
  Erik J. Søderlund, Sidney D. Nelson, Erik Dybing> ;Acta Pharmacologica Et Toxicologica. 2009 Mar 13
• 6 citations
  Genetic differences in dimethylnitrosamine mutagenicity in vitro associated with mouse hepatic aryl hydrocarbon hydroxylase activity induced by 3-methylcholanthrene.
  Tore Aune, Erik Dybing, Sidney D. Nelson, Snorri S. Thorgeirsson> ;Acta Pharmacologica Et Toxicologica. 2009 Mar 13
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