
Simon C. Robson MD PhD FAASLD (He/Him)
Gastrointestinal Cancer, Hepatology & Liver Transplantation, Inflammatory Bowel Disease
Professor, Medicine and Anesthesiology, Vice Chair Research, Beth Israel Deaconess Medical Center, Harvard Medical School
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330 Brookline AvenueBeth Israel Deaconess Medical CenterBoston, MA 02215
Phone+1 617-632-1070
Fax+1 617-632-1861
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Summary
- Physician Scientist with expertise in Hepatology and Inflammation.
Education & Training
- Beth Israel Deaconess Medical CenterPost-Doctoral Fellowship, 1993 - 1996
- University of Cape TownPhD, 1989
- Kings College HospitalMRCP, 1982 - 1983
- University of Cape Town Faculty of MedicineClass of 1978
Certifications & Licensure
- MA State Medical License 1997 - 2026
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Plenary and Keynote Lectures PURINES2018, PURINES2022, 2018, 2022
- John Hedley-Whyte Lectureship Anesthesia, BIDMC, 2021
- Subcommittee of Professors Harvard Medical School, 2018, 2020-2021
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Clinical Trials
- Identification of Genetic Causes of Calcific Aortic Valve Disease Start of enrollment: 2018 Sep 25
- Purinergic Signaling and the Postmenopausal Heart Start of enrollment: 2019 Jul 01
Publications & Presentations
PubMed
- Targeting the CD39/CD73 pathway: New insights into cardiac fibrosis and inflammation in female cardiac surgery patients.Eitezaz Mahmood, Mark Robitaille, Yifan Bu, Adnan Khan, Marie-France Poulin
Journal of Molecular and Cellular Cardiology Plus. 2025-06-01 - Endothelial -targeted CD39 is protective in a mouse model of global forebrain ischaemia.Natasha Ting Lee, Ioanna Savvidou, Carly Selan, David K Wright, Robert Brkljaca
Journal of Neuroinflammation. 2025-04-21 - Impact of Estrogen on Purinergic Signaling in Microvascular Disease.Jessica Cassavaugh, Maria Serena Longhi, Simon C Robson
International Journal of Molecular Sciences. 2025-02-27
Journal Articles
- Adenosine generation by CD39 and CD73 on T regulatory cells mediates immune suppressionDeaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M, Kuchroo VK, Strom TB, Robson SC, The Journal of Experimental Medicine, 1/1/2007
- Purinergic Signaling during InflammationEltzschig HK, Sitkovsky MV, Robson SC, N Engl J Med, 12/13/2012
- Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injuryNowak-Machen M, Schmelzle M, Hanidziar D, Junger W, Exley M, Otterbein L, Wu Y, Csizmadia E, Doherty G, Sitkovsky M, Robson SC, Am J Respir Cell Mol Biol, 5/1/2013
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Books/Book Chapters
Abstracts/Posters
- Lower Risk of Cardiac Rupture in CD39 Null Mice Post-myocardial InfarctionOgawa M, Ogawa N, Nakayama M, Csizmadia E, Enjyoji K, Kohzuki M, Robson SC, J. American College of Cardiology, 1/1/2005
- Adenosine A1 and A2A Receptors. CD39/CD73KO Influence Granulomatousresponses to BCGKara FM, Montesinos MC, Mor A, Robson SC, Thompson L, Cronstein BN, 8th International Symposium on Adenosine and Adenine Nucleotides, Ferrara, Italy, 5/1/2006
- Transcription Factor YY1 and the Retinoblastoma Protein Are Downstream Targets of CD39/ENTPD1 Signaling Pathways during Liver RegenerationWu Y, Imai M, Sun X, Csizmadia E, Enjyoji K, Choi C, Robson SC,Usheva A, Hepatology, 1/1/2005
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Lectures
- Vascular Biology of CD39 and Transplantation TopicsDepartment of Gastroenterology, BIDMC - 1/1/2013
- Vascular Bed-specific Characteristics of Endothelial CellsDepartment of Gastroenterology, Mount Sinai Hospital, NY - 1/1/2013
- Purinergic Signaling in the LiverLondon, UK - 1/1/2013
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Other
- Hepatic Xenotransplantation. Transplant Report
1/1/1995 - Contributions to Reports in Cape Times, Hepatitis B Immunizations and Liver TransplantationRobson
1/1/1993 - Audio-mix, and Pathways to HealthRadio Today
1/1/1993 - Join now to see all
Grant Support
- T cell genotype/phenotype influence on atherosclerotic cardiovascular disease.NIH2023–2027
- Targeting ENTPD3 to boost extracellular ATP and inflame tumors.Emerson Collective CRF2021–2023
- PGC-1α, Purines and the Postmenopausal Heart.NIH NIA2021–2023
- DAMP-Mediated Innate Immune Failure and Pneumonia .....DoD2016–2022
- Directed Purinergic Signaling as Immunotherapy in LeukemiaNIH NCI2018–2020
- Engineering Inhibitory Antibodies To Ectoenzymes For Cancer TreatmentNational Cancer Institute2012
- Thromboregulatory Barriers To XenotransplantationNational Institute Of Allergy And Infectious Diseases2000–2011
- Purinergic ThromboregulationNational Heart, Lung, And Blood Institute2009–2010
- Thromboregulatory Strategies To Prolong Xenograft Survival.National Institute Of Allergy And Infectious Diseases2006–2009
- Vascular Topography Of Cd39/NtpdasesNational Heart, Lung, And Blood Institute2004–2008
- Core--Histological SupportNational Heart, Lung, And Blood Institute2004–2008
- Functional Analysis Of Vascular NtpdasesNational Heart, Lung, And Blood Institute2000–2007
- Thromboregulatory Strategies To Prolong XenograftsNational Institute Of Allergy And Infectious Diseases2005
- Vascular Ntpdases And TransplantationNational Heart, Lung, And Blood Institute2001–2004
- Vascular Ecto Adpases And TransplantationNational Heart, Lung, And Blood Institute1997–2000
Committees
- Member, SOP HMS 2018 - 2021
Research History
- Vice Chair Research AnesthesiaDirector of Center for Inflammation Research2019 - Present
Professional Memberships
- AASLDMember
Other Languages
- Dutch
Industry Relationships
- Scientific Founder, ePURINES2018 - Present
- Scientific Founder, Purinomia2017 - Present
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