Sinisa Dovat MD

Pediatric Hematology & Oncology•Hershey, PA

Professor, Pediatrics, Pennsylvania State University College of Medicine

500 University DrHershey, PA 17033
Phone+1 800-243-1455
Fax+1 608-263-0440

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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Pediatric Hematology/Oncology, 1996 - 1999
Penn State Milton S Hershey Medical CenterResidency, Pediatrics, 1993 - 1996
University of Novi Sad Faculty of MedicineClass of 1988

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Certifications & Licensure

CA State Medical License 1996 - Present
PA State Medical License 1994 - 2026
WI State Medical License 2004 - 2021
American Board of Pediatrics Pediatric Hematology-Oncology

Publications & Presentations

PubMed

Pharmacological blockade of rho kinase enhances venetoclax responses in translational models of acute myeloid leukemia.
Upendarrao Golla, Riya Bhalodia, Charyguly Annageldiyev, Satyam Patel, Vishnu Sravan Bollu
Haematologica. 2026-10-01
Establishment of Patient-Derived Organoids for Pediatric Cancer Research.
Muhammad Younis, Tarlan Arjmandi, Mohammad Haque, Katherine McClain, Thussenthan Walter-Angelo
Cancers. 2026-05-02
Lineage-specific CK2α deletion reshapes the transcriptome of hematopoietic stem cells toward an immune-primed state.
Hannah Valensi, Rajesh Rajaiah, Marudhu Shanmugam, Daniyal Muhammad, Upendar Golla
Biorxiv. 2026-04-15

Abstracts/Posters

CK2 Inhibitor CX4945 Shows Strong In Vivo Synergistic Anti-Leukemia Activity with Rapamycin in B-ALL Due to Enhanced Ikaros Mediated Repression of mTOR Pathway
Sinisa Dovat, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
CK2 Inhibitor CX4945 Shows Strong In Vivo Anti Leukemia Effect in AML Via Augmented Ikaros-Mediated Regulation of Global Epigenetic Landscape
Sinisa Dovat, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Oncogenesis of CRLF2 Overexpression and Effect of JAK2 Inhibitor in CRLF2 Overexpressed B-Cell Acute Lymphoblastic Leukemia
Sinisa Dovat, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

The Novel Small Molecule Inhibitor KS99 Targets AML and Inhibits Stemness Markers STAT3 and ALDH
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Press Mentions

College of Medicine Awarded $4 Million Grant to Advance Pediatric Oncology ResearchSeptember 25th, 2024
College of Medicine Awarded $4 Million Grant to Advance Pediatric Oncology ResearchSeptember 25th, 2024
Increased Incidence of IKZF1 Deletions and IGH-CRLF2 Translocations in B-ALL of Hispanic/Latino Children—a Novel Health DisparityFebruary 2nd, 2021

Grant Support

Novel targeted therapy to reduce health disparities in pediatric leukemiaPENNSYLVANIA STATE UNIV HERSHEY MED CTR2023–2028
The Role Of Zinc Finger Genes In LeukemogenesisNational Heart, Lung, And Blood Institute2010–2011
The Role Of Zinc Finger Genes In LeukemogenesisNational Heart, Lung, And Blood Institute2009–2010
The Role Of Zinc Finger Genes In Cellular ProliferationNational Cancer Institute2005–2007
The Role Of Zinc Finger Genes In HematopoiesisNational Cancer Institute2003