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Sonali (Mehta) Smith, MD, Oncology, Chicago, IL

Sonali (Mehta) Smith MD

Oncology•Chicago, IL

Hematologic Oncology

Elwood V. Jensen Professor of Medicine, Section Chief of Hematology/Oncology, Co-Director of the Lymphoma Program, the University of Chicago Div of the Bio Sci The Pritzker School of Medicine

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  • 5841 S Maryland AveChicago, IL 60637

  • Phone+1 888-824-0200

  • Fax+1 773-702-3163

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Summary

  • Dr. Sonali Smith is an oncologist in Chicago, IL and is affiliated with University of Chicago Medical Center. She received her medical degree from Northwestern University Feinberg School of Medicine and has been in practice 23 years. She specializes in hematologic oncology and is experienced in Hodgkin and non-Hodgkin lymphoma.

Education & Training

  • University of Chicago
    University of ChicagoFellowship, Hematology and Medical Oncology, 1998 - 2001
  • McGaw Medical Center of Northwestern University
    McGaw Medical Center of Northwestern UniversityResidency, Internal Medicine, 1994 - 1997
  • Northwestern University The Feinberg School of Medicine
    Northwestern University The Feinberg School of MedicineClass of 1994

Certifications & Licensure

  • IL State Medical License
    IL State Medical License 1997 - 2029
  • WI State Medical License
    WI State Medical License 2022 - 2023
  • Medical Oncology
    American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

  • CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2014, 2016-2017
  • CMS Meaningful Use Stage 2 Certification EpicCare Inpatient 2014 Certified EHR Suite, Epic Systems Corporation, 2014, 2016-2017
  • CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2014, 2016-2017

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin’s Lymphoma  
    Sonali (Mehta) Smith, MD, The New England Journal of Medicine
  • Five-Year Follow-up of Lenalidomide plus Rituximab as Initial Treatment for Mantle Cell Lymphoma  
    Jia Ruan, Jakub Svoboda, John P Leonard, Sonali M Smith, Morton Coleman, Richard R Furman, Blood

Abstracts/Posters

  • A Phase 2 Study of the Dual SYK/JAK Inhibitor Cerdulatinib Demonstrates Good Tolerability and Clinical Response in Relapsed/Refractory Peripheral T-Cell Lymphoma and C...
    Sonali M. Smith, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
  • PET-Directed Therapy for Patients with Limited-Stage Diffuse Large B-Cell Lymphoma - Results of Intergroup Nctn Study S1001
    Sonali M. Smith, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
  • Beyond PD-1: Investigating the Therapeutic Potential of TIGIT Blockade in DLBCL
    Sonali M. Smith, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

  • Checkpoint Blockade Therapy May Sensitize Hodgkin Lymphoma to Subsequent Therapy 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
  • Five-Year Outcomes of SWOG S0: A Randomized Phase II US Intergroup Study of R-HCVAD Vs. R-Bendamustine Followed By Autologous Stem Cell Transplant for Patients with Ma... 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
  • Checkpoint Blockade Therapy May Sensitize Aggressive and Indolent Non-Hodgkin Lymphoma to Subsequent Therapy 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Press Mentions

  • What Would “The Pitt: Oncology” Really Look Like?
    What Would “The Pitt: Oncology” Really Look Like?August 24th, 2026
  • UChicago Medicine Highlights Research, Leadership, Clinical Advances at ASCO 2026
    UChicago Medicine Highlights Research, Leadership, Clinical Advances at ASCO 2026June 11th, 2026
  • UChicago Medicine Launches Miller Family Center for Rare Blood Cancers Thanks to Philanthropic Gift
    UChicago Medicine Launches Miller Family Center for Rare Blood Cancers Thanks to Philanthropic GiftDecember 10th, 2025

Grant Support

  • Developing an Oncology Workforce for the 21st CenturyUNIVERSITY OF CHICAGO2010–2025

Committees

  • Member, Committee on Appropriateness Criteria, Expert Panel on Radiation Oncology - Lymphoma, American College of Radiology 2015 - Present

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