SophieDarwicheMD

PubMed

• 1 citations
  Magnetic Resonance Arthrogram Outperforms Standard Magnetic Resonance Imaging 2 Weeks After First Shoulder Dislocation for Labral Tear Diagnosis.
  Ting Cong, Shaquille Charles, Justin J Greiner, Andrew Cordle, Carol Andrews, Rajiv P Reddy, Matthew Como, Nicholas Drain, Bryson P Lesniak, Sophie Darwiche, Jonathan ...> ;Arthroscopy. 2024 Feb 23
• 13 citations
  Toll-Like Receptor 4 on both Myeloid Cells and Dendritic Cells Is Required for Systemic Inflammation and Organ Damage after Hemorrhagic Shock with Tissue Trauma in Mice.
  Kent R. Zettel, Sebastian Korff, Ruben Zamora, Adrian E. Morelli, Sophie Darwiche, Patricia Loughran, Greg Elson, Limin Shang, Susana Salgado-Pires, Melanie J. Scott, ...> ;Frontiers in Immunology. 2017 Nov 28
• 8 citations
  Sirtuin 1 Agonist Minimizes Injury and Improves the Immune Response Following Traumatic Shock.
  Jason Luciano, Benjamin Kautza, Sophie Darwiche, Silvia Martinez, Sladjana Stratimirovic, Paul Waltz, Jason L. Sperry, Matthew R. Rosengart, Sruti Shiva, Brian S. Zuck...> ;Shock. 2015 Aug 1
• 83 citations
  Adenosine monophosphate-activated protein kinase activation protects against sepsis-induced organ injury and inflammation.
  Daniel Escobar, Ana M. Botero-Quintero, Benjamin Kautza, Jason Luciano, Patricia Loughran, Sophie Darwiche, Matthew R. Rosengart, Brian S. Zuckerbraun, Hernando Gomez> ;The Journal of Surgical Research. 2015 Mar 1
• 28 citations
  Anti-HMGB1 Monoclonal Antibody Ameliorates Immunosuppression after Peripheral Tissue Trauma: Attenuated T-Lymphocyte Response and Increased Splenic CD11b+Gr-1+ Myeloid...
  Xiangcai Ruan, Sophie Darwiche, Changchun Cai, Melanie J. Scott, Hans-Christoph Pape, Timothy R. Billiar> ;Mediators of Inflammation. 2015 Jan 29
• 19 citations
  Selective roles for toll-like receptors 2, 4, and 9 in systemic inflammation and immune dysfunction following peripheral tissue injury.
  Sophie Darwiche, Xiangcai Ruan, Marcus K. Hoffman, Kent R. Zettel, Aaron P. Tracy, Linda M.I. Schroeder, Changchun Cai, Rosemary A. Hoffman, Melanie J. Scott, Hans-Chr...> ;The Journal of Trauma and Acute Care Surgery. 2013 Jun 1
• 20 citations
  Cumulative Effects of Bone and Soft Tissue Injury on Systemic Inflammation: A Pilot Study
  Roman Pfeifer, Sophie Darwiche, Lauryn Kohut, Timothy R. Billiar, Hans-Christoph Pape> ;Clinical Orthopaedics and Related Research. 2013 Mar 12
• 17 citations
  Inducible nitric oxide synthase contributes to immune dysfunction following trauma.
  Sophie Darwiche, Roman Pfeifer, Christoph L. Menzel, Xiangcai Ruan, Marcus K. Hoffman, Changchun Cai, R. Savanh Chanthaphavong, Patricia Loughran, Bruce R. Pitt, Rosem...> ;Shock. 2012 Nov 1
• 29 citations
  Mast cells play a critical role in the systemic inflammatory response and end-organ injury resulting from trauma.
  Changchun Cai, Zongxian Cao, Patricia Loughran, Sodam Kim, Sophie Darwiche, Sebastian Korff, Timothy R. Billiar> ;Journal of the American College of Surgeons. 2011 Nov 1
• 21 citations
  The timing of definitive fixation for major fractures in polytrauma—A matched-pair comparison between a US and European level I centres: Analysis of current fracture m...
  Verena M. Schreiber, Ivan S. Tarkin, Frank Hildebrand, Sophie Darwiche, Roman Pfeifer, Jaques Chelly, Peter V. Giannoudis, Hans-Christoph Pape> ;Injury. 2011 Jul 1
• 22 citations
  Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
  Lauryn Kohut, Sophie Darwiche, John Brumfield, Alicia Frank, Timothy R. Billiar> ;Journal of Visualized Experiments. 2011 Jun 6
• 30 citations
  Pseudofracture: an acute peripheral tissue trauma model.
  Sophie Darwiche, Philipp Kobbe, Roman Pfeifer, Lauryn Kohut, Hans-Christoph Pape, Timothy R. Billiar> ;Journal of Visualized Experiments. 2011 Apr 18
• 25 citations
  Models of lower extremity damage in mice: time course of organ damage and immune response.
  Christoph L. Menzel, Roman Pfeifer, Sophie Darwiche, Philipp Kobbe, Roop Gill, Richard A. Shapiro, Patricia Loughran, Yoram Vodovotz, Melanie J. Scott, Mazen S. Zenati...> ;The Journal of Surgical Research. 2011 Apr 1
• 30 citations
  Role of hemorrhage in the induction of systemic inflammation and remote organ damage: analysis of combined pseudo-fracture and hemorrhagic shock.
  Roman Pfeifer, Philipp Kobbe, Sophie Darwiche, Timothy R. Billiar, Hans-Christoph Pape> ;Journal of Orthopaedic Research. 2011 Feb 1
• 24 citations
  Complement factor 3 deficiency attenuates hemorrhagic shock-related hepatic injury and systemic inflammatory response syndrome
  Changchun Cai, Roop Gill, Hyun-Ae Eum, Zongxian Cao, Patricia Loughran, Sophie Darwiche, Rebecca D. Edmonds, Christoph L. Menzel, Timothy R. Billiar> ;American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 2010 Nov 1
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