SosipatrosBoikosMD

PubMed

• 5 citations
  POU2AF3-rearranged sarcomas: A novel tumor defined by fusions of EWSR1 or FUS to a gene formerly designated COLCA2.
  Matthew C Hiemenz, Jaspreet Kaur, Zheng Kuang, Richard S P Huang, Lukas Harries, Dana Metzger, Kelsie Schiavone, Sherri Z Millis, Douglas I Lin, Mirna Lechpammer, Bren...> ;Genes, Chromosomes & Cancer. 2023 Aug 1
• 2 citations
  Genomic screening reveals ubiquitin-like modifier activating enzyme 1 as a potent and druggable target in c-MYC-high triple negative breast cancer models.
  Sheeba Jacob, Tia H Turner, Jinyang Cai, Konstantinos V Floros, Ann K Yu, Colin M Coon, Rishabh Khatri, Mohammad A Alzubi, Charles T Jakubik, Ynes M Bouck, Madhavi Puc...> ;PNAS Nexus. 2022 Nov 1
• 4 citations
  Pharmacologic Inhibition of SHP2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1.
  Kurupi, R., Floros, K., Jacob, S., Chawla, A., Cai, J., Hu, B., Puchalapalli, M., Coon, C., Khatri, R., Crowther, G., Egan, R., Murchie, E., Greninger, P., Dalton, K.,...> ;Cancer Research Communications. 2022 Sep 1
• 8 citations
  High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition.
  Jinyang Cai, Sheeba Jacob, Richard Kurupi, Krista M Dalton, Colin Coon, Patricia Greninger, Regina K Egan, Giovanna T Stein, Ellen Murchie, Joseph McClanaghan, Yuta Ad...> ;Cell Reports. 2022 Jul 26
• 5 citations
  MYCN upregulates the transsulfuration pathway to suppress the ferroptotic vulnerability in-amplified neuroblastoma.
  Konstantinos V Floros, Ayesha T Chawla, Mia O Johnson-Berro, Rishabh Khatri, Angeliki M Stamatouli, Sosipatros A Boikos, Mikhail G Dozmorov, L Ashley Cowart, Anthony C...> ;Cell Stress. 2022 Feb 1
• The cytologic features of primary pseudomyogenic hemangioendothelioma of bone.
  Bryce Hatfield, Steven C Smith, Sosipatros A Boikos, Sadia Sayeed> ;Diagnostic Cytopathology. 2021 Oct 12
• 6 citations
  Pharmaceutical Interference of the EWS-FLI1-driven Transcriptome By Cotargeting H3K27ac and RNA Polymerase Activity in Ewing Sarcoma.
  Daniel A. R. Heisey, Sheeba Jacob, Timonthy L Lochmann, Richard Kurupi, Maninderjit S. Ghotra, Marissa L. Calbert, Mayuri Shende, Yuki Kato Maves, Jennifer E. Koblinsk...> ;Molecular Cancer Therapeutics. 2021 Jul 26
• 6 citations
  Unmasking BCL-2 Addiction in Synovial Sarcoma by Overcoming Low NOXA.
  Carter K. Fairchild, Konstantinos V. Floros, Sheeba Jacob, Colin M. Coon, Madhavi Puchalapalli, Bin Hu, Hisashi Harada, Mikhail G. Dozmorov, Jennifer E. Koblinski, Ste...> ;Cancers. 2021 May 12
• 1 citations
  Intimal sarcoma of the pulmonary artery treated with neoadjuvant radiation prior to pulmonary artery resection and reconstruction.
  Alexander Allen, Steven C. Smith, Raghavendra Pillappa, Sosipatros A. Boikos, Benjamin Medalion, John D. Grizzard, Anthony D. Cassano, Timothy Harris> ;Respiratory Medicine Case Reports. 2021 Apr 27
• 60 citations
  MYCN-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis
  Konstantinos V. Floros, Jinyang Cai, Sheeba Jacob, Richard Kurupi, Carter K. Fairchild, Mayuri Shende, Colin M. Coon, Krista M. Powell, Benjamin R. Belvin, Bin Hu, Mad...> ;Cancer Research. 2021 Apr 1
• 9 citations
  Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN -amplified neuroblastoma.
  Krista M. Dalton, Timothy L. Lochmann, Konstantinos V. Floros, Marissa L. Calbert, Richard Kurupi, Giovanna T. Stein, Joseph McClanaghan, Ellen Murchie, Regina K. Egan...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Mar 30
• 12 citations
  Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors.
  Konstantinos V. Floros, Sheeba Jacob, Richard Kurupi, Carter K. Fairchild, Bin Hu, Madhavi Puchalapalli, Jennifer E. Koblinski, Mikhail G. Dozmorov, Sosipatros A. Boik...> ;Cell Death & Disease. 2021 Feb 15
• 4 citations
  A Reappraisal of Superficial Pleomorphic Liposarcoma.
  Scott Hilliard Berg, Cathy M. Massoud, Colleen Jackson-Cook, Sosipatros Alexander Boikos, Steven C. Smith, Mark C. Mochel> ;American Journal of Clinical Pathology. 2020 Aug 5
• Respecting your elders: osimertinib demonstrates preferential activity in elderly patients with T790M positive non-small cell lung cancers.
  Hiromichi Ebi, Sosipatros A. Boikos, Anthony C. Faber> ;Journal of Thoracic Disease. 2019 Sep 1
• 3 citations
  Paragangliomas in Carney-Stratakis Syndrome.
  Arushi Khurana, Lin Mei, Anthony C. Faber, Steven C. Smith, Sosipatros A. Boikos> ;Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 2019 Jun 7
• Correction: Prognostic Factors of Malignant Pheochromocytoma and Paraganglioma: A Combined SEER and TCGA Databases Review.
  Lin Mei, Arushi Khurana, Taha Al-Juhaishi, Anthony Faber, Francesco Celi, Steven Smith, Sosipatros Boikos> ;Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 2019 Jul 1
• 4 citations
  Prognostic Factors of Malignant Pheochromocytoma and Paraganglioma: A Combined SEER and TCGA Databases Review.
  Lin Mei, Arushi Khurana, Taha Al-Juhaishi, Anthony Faber, Francesco Celi, Steven Smith, Sosipatros Boikos> ;Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 2019 Jul 1
• 20 citations
  The Ewing Family of Tumors Relies on BCL-2 and BCL-XL to Escape PARP Inhibitor Toxicity
  Daniel A. R. Heisey, Timothy L. Lochmann, Konstantinos V. Floros, Colin M. Coon, Krista M. Powell, Sheeba Jacob, Marissa L. Calbert, Maninderjit S. Ghotra, Giovanna T....> ;Clinical Cancer Research. 2019 Mar 1
• 30 citations
  Increased Synthesis of MCL-1 Protein Underlies Initial Survival of EGFR-Mutant Lung Cancer to EGFR Inhibitors and Provides a Novel Drug Target.
  Kyung-A Song, Yasuyuki Hosono, Crystal Turner, Sheeba Jacob, Timothy L. Lochmann, Yoshiko Murakami, Neha U. Patel, Jungoh Ham, Bin Hu, Krista M. Powell, Colin M. Coon,...> ;Clinical Cancer Research. 2018 Nov 15
• 34 citations
  Advances and Challenges on Management of Gastrointestinal Stromal Tumors
  Lin Mei, Wei Du, Michael O. Idowu, Margaret von Mehren, Sosipatros A. Boikos> ;Frontiers in Oncology. 2018 May 7
• 21 citations
  Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy.
  Konstantinos V. Floros, Timothy L. Lochmann, Bin Hu, Carles Monterrubio, Mark T. Hughes, Jason D. Wells, Cristina Bernadó Morales, Maninderjit S. Ghotra, Carlotta Cost...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb 23
• 22 citations
  Classification of gastrointestinal stromal tumor syndromes.
  Priya Gopie, Lin Mei, Anthony C. Faber, Steven R. Grossman, Steven C. Smith, Sosipatros A. Boikos> ;Endocrine-Related Cancer. 2018 Feb 1
• 74 citations
  Venetoclax is effective in small cell lung cancers with high BCL-2 expression
  Timothy L. Lochmann, Konstantinos V. Floros, Mitra Naseri, Krista M. Powell, Wade Cook, Ryan J. March, Giovanna T. Stein, Patricia Greninger, Yuki Kato Maves, Laura Sa...> ;Clinical Cancer Research. 2018 Jan 15
• 52 citations
  Surgical Management of Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Pediatric and Wildtype GIST Clinic
  Christopher B. Weldon, Arin L. Madenci, Sosipatros A. Boikos, Katherine A. Janeway, Suzanne George, Margaret von Mehren, Alberto S. Pappo, Joshua D. Schiffman, Jennife...> ;Journal of Clinical Oncology. 2017 Feb 10
• 51 citations
  Gastrointestinal Stromal Tumors: The GIST of Precision Medicine
  Lin Mei, Steven C. Smith, Anthony C. Faber, Jonathan C. Trent, Steven R. Grossman, Constantine A. Stratakis, Sosipatros A. Boikos> ;Trends in Cancer. 2017 Dec 1
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Journal Articles

• The Ewing Family of Tumors Rely on BCL-2 and BCL-XL to Escape PARP Inhibitor Toxicity  
  Steven C Smith, Sosipatros A Boikos, Anthony C Faber, Clinical Cancer Research
• Increased Synthesis of MCL-1 Protein Underlies Initial Survival of EGFR Mutant Lung Cancer to EGFR Inhibitors and Provides a Novel Drug Target  
  Aaron N Hata, Sosipatros A Boikos, Anthony C Faber, Clinical Cancer Research