SrinivasaEdaraMD

PubMed

• Expression of the inactive C145A mutant human O6-alkylguanine-DNA alkyltransferase in E.coli increases cell killing and mutations by N-methyl-N''-nitro-N-nitrosoguanid...
  Edara, S., Kanugula, S., Pegg, A. E.> ;Carcinogenesis. 1999 Jan
• Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
  Goodtzova, K., Kanugula, S., Edara, S., Pegg, A. E.> ;Biochemistry. 1998 Sep 8
• Reaction of O6-benzylguanine-resistant mutants of human O6-alkylguanine-DNA alkyltransferase with O6-benzylguanine in oligodeoxyribonucleotides.
  Pegg, A. E., Kanugula, S., Edara, S., Pauly, G. T., Moschel, R. C., Goodtzova, K.> ;J Biol Chem. 1998 May 1
• Repair of O6-benzylguanine by the Escherichia coli Ada and Ogt and the human O6-alkylguanine-DNA alkyltransferases.
  Goodtzova, K., Kanugula, S., Edara, S., Pauly, G. T., Moschel, R. C., Pegg, A. E.> ;J Biol Chem. 1997 Mar 28
• Resistance of the human O6-alkylguanine-DNA alkyltransferase containing arginine at codon 160 to inactivation by O6-benzylguanine.
  Edara, S., Kanugula, S., Goodtzova, K., Pegg, A. E.> ;Cancer Res. 1996 Dec 15
• Mutations in human O6-alkylguanine-DNA alkyltransferase imparting resistance to O6-benzylguanine.
  Crone, T. M., Goodtzova, K., Edara, S., Pegg, A. E.> ;Cancer Res. 1994 Dec 1
• Alteration of arginine-128 to alanine abolishes the ability of human O6-alkylguanine-DNA alkyltransferase to repair methylated DNA but has no effect on its reaction wi...
  Kanugula, S., Goodtzova, K., Edara, S., Pegg, A. E.> ;Biochemistry. 1995 May 30
• The role of tyrosine-158 in O6-alkylguanine-DNA alkyltransferase activity.
  Edara, S., Goodtzova, K., Pegg, A. E.> ;Carcinogenesis. 1995 Jul
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