Stephanie Halene MD

PubMed

• Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow.
  Esen Sefik, William Philbrick, Fengrui Zhang, Kriti Agrawal, Brian Van Lee
  Proceedings of the National Academy of Sciences of the United States of America. 2025-09-23
• 1 citations
  RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and Wnt pathway activation.
  Madeline Y Mayday, Giulia Biancon, Manyi Wei, Christian Ramirez, Irene Moratti
  Blood. 2025-08-28
• In the time of COVID-19: challenges, successes, and lessons learned from studies in cancer patients.
  Philip C Mack, James M Crawford, Andres Chang, Anna Yin, Sabra L Klein
  Journal of the National Cancer Institute. 2025-08-01

Journal Articles

• SRSF2 Mutations Drive Oncogenesis by Activating a Global Program of Aberrant Alternative Splicing in Hematopoietic Cells  
  Radovan Vasic, Stephanie Halene, Nature

Abstracts/Posters

• Variable Response to BCL2 Inhibition in MDS Is Enhanced across MDS Subtypes with Synergistic Combination of BCL2+MCL1 Inhibition
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Immune Checkpoint Inhibitor Therapy for Acute Myeloid Leukemia and Higher-Risk Myelodysplastic Syndromes: A Single-Center Experience
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• LAM-003, a Novel Oral Heat Shock Protein 90 Inhibitor for Treatment of Acute Myeloid Leukemia, Including Wild-Type and FMS-like Tyrosine Kinase 3 (FLT3)-Mutant Disease
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• U2AF1 Driver Mutations in Hematopoietic Disorders Alter but Do Not Abrogate RNA Binding and Enlighten Structural Dependencies of the U2AF-RNA Complex
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• In Vivo reconstruction of Human Erythropoiesis with Circulating Mature Human RBCs in Humanized Liver Mistrg Mice
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• PARP Inhibitors Are Effective in IDH1/2 Mutant MDS and AML Resistant to Targeted IDH Inhibitors
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• The GPR68/BCL2 Axis Remodels Metabolism in AML By Relocating Calcium
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Ivo-Nivo: A Phase II Study of the IDH1 Inhibitor Ivosidenib (AG-120) in Combination with the Checkpoint Blockade Inhibitor Nivolumab for Patients with IDH1 Mutated Rel...
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• The PRIME Trial: PARP Inhibition in IDH Mutant Effectiveness Trial. a Phase II Study of Olaparib in Isocitrate Dehydrogenase (IDH) Mutant Relapsed/Refractory Acute Mye...
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Innate Immune Response and Hematopoietic Failure
  Stephanie Halene, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
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Lectures

• Proton Sensor GPR68 Is Essential to Maintain Myeloid Malignancies 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018