StephenLLeeMD

Neurology • Lebanon, NH

Movement Disorder, Neurodegenerative, Neurocritical Care

Assistant Professor, Neurology, Geisel School of Medicine

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Office
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon, NH 03756
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Education & Training

Vanderbilt UniversityResearch Fellowship, 2001 - 2002
Vanderbilt University Medical CenterMovement Disorders, Movement Disorders, PG-MSTP, 2001 - 2002
Washington University/B-JH/SLCH ConsortiumResidency, Neurology, 1998 - 2001
Washington University/B-JH/SLCH ConsortiumInternship, Internal Medicine, 1997 - 1998
Washington University in St. Louis School of MedicineClass of 1997

Certifications & Licensure

NH State Medical License 2004 - 2025
VT State Medical License 2022 - 2024
ME State Medical License 2020 - 2021
TN State Medical License 2001 - 2006
MO State Medical License 1998 - 2001
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011, 2013

Clinical Trials

Efficacy of Isradipine in Early Parkinson Disease Start of enrollment: 2014 Nov 01
Completed
Phase 3
Prism Adaptation Treatment of Parkinson's Disease Start of enrollment: 2015 Feb 01
Completed
Not Applicable

Publications & Presentations

PubMed

3 citations
Two weeks of twice-daily prism adaptation treatment does not improve posture or gait in Parkinson's disease: a double-blind randomized controlled trial.
Janet H. Bultitude, Dawna Pidgeon, Pauline R LeBlanc, Charlotte A Jeffreys, Faith P. Alexandre, Stephen L. Lee> ;Trials. 2021 Jun 14
32 citations
Plasma-borne indicators of inflammasome activity in Parkinson's disease patients.
Faith L Anderson, Katharine M. von Herrmann, Angeline S. Andrew, Yuliya I. Kuras, Alison L. Young, Clemens R. Scherzer, William F. Hickey, Stephen L. Lee, Matthew C. H...> ;NPJ Parkinson's Disease. 2021 Jan 4
1 citations
Lifestyle Factors and Parkinson's Disease Risk in a Rural New England Case-Control Study.
Angeline S. Andrew, Faith L Anderson, Stephen L. Lee, Katharine M. von Herrmann, Matthew C. Havrda> ;Parkinson's Disease. 2021 Jul 2
108 citations
NLRP3 expression in mesencephalic neurons and characterization of a rare NLRP3 polymorphism associated with decreased risk of Parkinson's disease.
Katharine M. von Herrmann, Lucas A. Salas, Eileen M. Martinez, Alison L. Young, Joseph M. Howard, Mary S. Feldman, Brock C. Christensen, Owen M. Wilkins, Stephen L. Le...> ;NPJ Parkinson's Disease. 2018 Aug 15
24 citations
Factors associated with falling in early, treated Parkinson's disease: The NET-PD LS1 cohort
Kelvin L. Chou, Jordan J. Elm, Catherine L. Wielinski, David Simon, Michael J. Aminoff, Chadwick W. Christine, Grace S. Liang, Robert A. Hauser, Lewis Sudarsky, Chizob...> ;Journal of the Neurological Sciences. 2017 Jun 15
8 citations
Therapeutic plasma exchange as a steroid-sparing therapy in a patient with limbic encephalitis due to antibodies to voltage-gated potassium channels.
Isabella W. Martin, Christi-Lynn B. Martin, Nancy M. Dunbar, Stephen L. Lee, Zbigniew M. Szczepiorkowski> ;Journal of Clinical Apheresis. 2016 Feb 1
163 citations
Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial
Tanya Simuni, Karl Kieburtz, Barbara C. Tilley, Jordan J. Elm, Bernard Ravina, Debra Babcock, Marina E. Emborg, Robert A. Hauser, Cornelia Kamp, John C. Morgan, G. Web...> ;The Lancet. Neurology. 2015 Aug 1
13 citations
Parkinson disease loci in the mid-western Amish
Mary F. Davis, Anna C. Cummings, Lan Jiang, D.R. Velez Edwards, Renee Laux, Lori Reinhart-Mercer, Denise Fuzzell, William K. Scott, Margaret A. Pericak-Vance, Stephen ...> ;Human Genetics. 2013 Jun 21
Carfilzomib in Multiple Myeloma Patients with Renal Impairment: Pharmacokinetics and Safety
S Lee, A Z Badros, T Martin> ;Nature.
7 citations
Time-Dependent Statistical and Correlation Properties of Neural Signals during Handwriting
Valery I. Rupasov, Mikhail A. Lebedev, Joseph S. Erlichman, Stephen L. Lee, James C. Leiter, Michael Linderman> ;Plos One. 2012 Sep 11
6 citations
A Genome‐Wide Linkage Screen in the Amish with Parkinson Disease Points to Chromosome 6
Anna C. Cummings, Stephen L. Lee, Jacob L. McCauley, Lan Jiang, Amy E. Crunk, Lynne L. McFarland, Paul Gallins, Denise Fuzzell, Clare Knebusch, Charles E. Jackson, Wil...> ;Annals of Human Genetics. 2011 May 1
19 citations
Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging...
Chantel D. Sloan, Li Shen, John D. West, Heather A. Wishart, Laura A. Flashman, Laura A. Rabin, Robert B. Santulli, Stephen J. Guerin, C. Harker Rhodes, Gregory J. Tso...> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2010 Jul 1
11 citations
A genome-wide scan in an Amish pedigree with parkinsonism.
Stephen L. Lee, Deborah G. Murdock, Jacob L. McCauley, Yuki Bradford, Amy E. Crunk, Lynne L. McFarland, L. Jiang, T. Wang, Nathalie Schnetz-Boutaud, Jonathan L. Haines> ;Annals of Human Genetics. 2008 Sep 1
44 citations
GPNN: Power studies and applications of a neural network method for detecting gene-gene interactions in studies of human disease
Alison A. Motsinger, Stephen L. Lee, George D. Mellick, Marylyn D. Ritchie> ;BMC Bioinformatics. 2006 Jan 25
26 citations
Familial dementia with Lewy bodies: Clinicopathologic analysis of two kindreds
James E. Galvin, Stephen L. Lee, Arie Perry, N. Havlioglu, Daniel W. McKeel, John C. Morris> ;Neurology. 2002 Oct 8
1 citations
Predictors of effective bilateral subthalamic nucleus stimulation for PD.
P D Charles, N Van Blercom, P Krack, S L Lee, J Xie, G Besson, A-L Benabid, P Pollak> ;Neurology. 2002 Sep 24
27 citations
Characterization of the circadian system of NGFI-A and NGFI-A/NGFI-B deficient mice.
Thomas S. Kilduff, C. Vugrinic, Stephen L. Lee, Jeffrey Milbrandt, Jens D. Mikkelsen, Bruce F. O'Hara, H. C. Heller> ;Journal of Biological Rhythms. 1998 Aug 1
155 citations
TISSUE FACTOR TRANSCRIPTION DRIVEN BY EGR-1 IS A CRITICAL MECHANISM OF MURINE PULMONARY FIBRIN DEPOSITION IN HYPOXIA
Shi Fang Yan, Yu Shan Zou, Yun Gao, Chao Zhai, Nigel Mackman, Stephen L. Lee, Jeffrey Milbrandt, David J. Pinsky, Walter Kisiel, David M. Stern> ;Proceedings of the National Academy of Sciences of the United States of America. 1998 Jul 7
416 citations
Luteinizing Hormone Deficiency and Female Infertility in Mice Lacking the Transcription Factor NGFI-A (Egr-1)
Stephen L. Lee, Yoel Sadovsky, Alexander H. Swirnoff, Jeffrey A. Polish, Pam Goda, Galina Gavrilina, Jeffrey Milbrandt> ;Science. 1996 Aug 30
83 citations
Unimpaired macrophage differentiation and activation in mice lacking the zinc finger transplantation factor NGFI-A (EGR1).
Stephen L. Lee, Y Wang, Jeffrey Milbrandt> ;Molecular and Cellular Biology. 1996 Aug 1
120 citations
Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice.
Peter A. Crawford, Yoel Sadovsky, Karen G. Woodson, Stephen L. Lee, Jeffrey Milbrandt> ;Molecular and Cellular Biology. 1995 Aug 1
229 citations
Unimpaired Thymic and Peripheral T Cell Death in Mice Lacking the Nuclear Receptor NGFI-B (Nur77)
Stephen L. Lee, Robin L. Wesselschmidt, Gerald P. Linette, Osami Kanagawa, John H. Russell, Jeffrey Milbrandt> ;Science. 1995 Jul 28
153 citations
Growth and differentiation proceeds normally in cells deficient in the immediate early gene NGFI-A.
Stephen L. Lee, LeAnne C. Tourtellotte, Robin L. Wesselschmidt, Jeffrey Milbrandt> ;The Journal of Biological Chemistry. 1995 Apr 28
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Hospital Affiliations

Dartmouth-Hitchcock Medical CenterLebanon, New Hampshire