StephenPlymateMD

PubMed

• A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer.
  Takuma Uo, Kayode K Ojo, Cynthia C T Sprenger, Kathryn Soriano Epilepsia, B Gayani K Perera, Mamatha Damodarasamy, Shihua Sun, Soojin Kim, Hannah H Hogan, Matthew A Hu...> ;Molecular Cancer Therapeutics. 2024 Mar 20
• Thio-2 inhibits key signaling pathways required for the development and progression of castration resistant prostate cancer.
  Antje Neeb, Ines Figueiredo, Denisa Bogdan, Laura Cato, Jutta Stober, Juan M Jiménez-Vacas, Victor Gourain, Irene I Lee, Rebecca Seeger, Claudia Muhle-Goll, Bora Gurel...> ;Molecular Cancer Therapeutics. 2024 Feb 27
• The Prostate Cancer Active Lifestyle Study (PALS): A randomized controlled trial of diet and exercise in overweight and obese men on active surveillance.
  Jonathan L Wright, Jeannette M Schenk, Roman Gulati, Sarah J Beatty, Matthew VanDoren, Daniel W Lin, Michael P Porter, Colm Morrissey, Atreya Dash, John L Gore, Ruth E...> ;Cancer. 2024 Feb 14
• Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts.
  Sychev, Z., Day, A., Bergom, H., Larson, G., Ali, A., Ludwig, M., Boytim, E., Coleman, I., Corey, E., Hwang, J., Drake, J., Plymate, S., Nelson, P.> ;Molecular Cancer Research. 2024 Feb 12
• Development and Validation of a New BAG-1L-Specific Antibody to Quantify BAG-1L Protein Expression in Advanced Prostate Cancer.
  Antje Neeb, Ines Figueiredo, Bora Gurel, Daniel Nava Rodrigues, Jan Rekowski, Ruth Riisnaes, Ana Ferreira, Susana Miranda, Mateus Crespo, Daniel Westaby, Maria de Los ...> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2023 Nov 1
• Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts.
  Zoi E Sychev, Abderrahman Day, Hannah E Bergom, Gabrianne Larson, Atef Ali, Megan Ludwig, Ella Boytim, Ilsa Coleman, Eva Corey, Stephen R Plymate, Peter S Nelson, Just...> ;Biorxiv. 2023 Aug 5
• 1 citations
  Supraphysiological Androgens Promote the Tumor Suppressive Activity of the Androgen Receptor through cMYC Repression and Recruitment of the DREAM Complex.
  Michael D Nyquist, Ilsa M Coleman, Jared M Lucas, Dapei Li, Brian Hanratty, Hannah Meade, Elahe A Mostaghel, Stephen R Plymate, Eva Corey, Michael C Haffner, Peter S N...> ;Cancer Research. 2023 Sep 1
• 1 citations
  The androgen receptor.
  Greg Van-Duyne, Ian A Blair, Cynthia Sprenger, Vera Moiseenkova-Bell, Stephen Plymate, Trevor M Penning> ;Vitamins and Hormones. 2023 Jan 1
• ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer.
  Song Yi Bae, Hannah E Bergom, Abderrahman Day, Joseph T Greene, Zoi E Sychev, Gabrianne Larson, Eva Corey, Stephen R Plymate, Tanya S Freedman, Justin H Hwang, Justin ...> ;Frontiers in Endocrinology. 2023 Jan 1
• Re: Heng Li, Yucong Zhang, Dong Li, et al. Androgen Receptor Splice Variant 7 Predicts Shorter Response in Patients with Metastatic Hormone-sensitive Prostate Cancer R...
  Adam G Sowalsky, Stephen R Plymate, Michael C Haffner, Johann S de Bono, Adam Sharp> ;European Urology. 2022 Nov 1
• 5 citations
  Druggable Metabolic Vulnerabilities Are Exposed and Masked during Progression to Castration Resistant Prostate Cancer.
  Stephen Y C Choi, Caroline Fidalgo Ribeiro, Yuzhuo Wang, Massimo Loda, Stephen R Plymate, Takuma Uo> ;Biomolecules. 2022 Oct 28
• 6 citations
  Assessment of Androgen Receptor Splice Variant-7 as a Biomarker of Clinical Response in Castration-Sensitive Prostate Cancer.
  Adam G Sowalsky, Ines Figueiredo, Rosina T Lis, Ilsa Coleman, Bora Gurel, Denisa Bogdan, Wei Yuan, Joshua W Russo, John R Bright, Nichelle C Whitlock, Shana Y Trostel,...> ;Clinical Cancer Research. 2022 Aug 15
• 3 citations
  Starving lethal prostate cancer by targeting heat shock proteins and glycolytic enzymes.
  Stephen R Plymate, Cynthia Sprenger, Michael C Haffner> ;Cell Reports. Medicine. 2022 Feb 15
• 13 citations
  Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth.
  Michael D Nyquist, Lisa S Ang, Alexandra Corella, Ilsa M Coleman, Michael P Meers, Anthony J Christiani, Cordell Pierce, Derek H Janssens, Hannah E Meade, Arnab Bose, ...> ;The Journal of Clinical Investigation. 2021 Jun 15
• 9 citations
  Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth.
  Michael D Nyquist, Lisa S Ang, Alexandra Corella, Ilsa M Coleman, Michael P Meers, Anthony J Christiani, Cordell Pierce, Derek H Janssens, Hannah E Meade, Arnab Bose, ...> ;The Journal of Clinical Investigation. 2021 May 17
• 110 citations
  Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling.
  Lauren Brady, Michelle Kriner, Ilsa Coleman, Colm Morrissey, Martine Roudier, Lawrence D. True, Roman Gulati, Stephen R. Plymate, Zoey Zhou, Brian Birditt, Rhonda Mere...> ;Nature Communications. 2021 Mar 3
• 19 citations
  CD38 in Advanced Prostate Cancers.
  Christina Guo, Mateus Crespo, Bora Gurel, David Dolling, Jan Rekowski, Adam Sharp, Antonella Petremolo, Semini Sumanasuriya, Daniel Nava Rodrigues, Ana Ferreira, Rita ...> ;European Urology. 2021 Jun 1
• 16 citations
  JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer
  Alec Paschalis, Jonathan Welti, Antje Neeb, Wei Yuan, Ines Figueiredo, Rita Pereira, Ana Ferreira, Ruth Riisnaes, Daniel Nava Rodrigues, Juan M. Jiménez-Vacas, Soojin ...> ;Cancer Research. 2021 Feb 15
• Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer.
  Irfan Asangani, Ian A Blair, Gregory Van Duyne, Vincent J Hilser, Vera Moiseenkova-Bell, Stephen Plymate, Cynthia Sprenger, A Joshua Wand, Trevor M Penning> ;The Journal of Biological Chemistry. 2021 Jan 9
• 36 citations
  Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer.
  Takuma Uo, Cynthia C. Sprenger, Stephen R. Plymate> ;Frontiers in Oncology. 2020 Oct 9
• 1 citations
  AR-V7 biomarker testing for primary prostate cancer: The ongoing challenge of analytical validation and clinical qualification.
  Adam G. Sowalsky, Adam Sharp, Shana Y. Trostel, Johann S. de Bono, Stephen R. Plymate> ;Cancer Treatment and Research Communications. 2021 Jan 1
• 48 citations
  A phase I dose-escalation study of enzalutamide in combination with the AKT inhibitor AZD5363 (capivasertib) in patients with metastatic castration-resistant prostate ...
  Michael Kolinsky, Pasquale Rescigno, Diletta Bianchini, Zafeiris Zafeiriou, Niven Mehra, Joaquin Mateo, Vasiliki Michalarea, Ruth Riisnaes, Mateus Crespo, Ines Figueir...> ;Annals of Oncology. 2020 May 1
• Clinical Acumen Versus Androgen Receptor Variant 7 Circulating Tumor Cells in Decision-Making for Men with Advanced Prostate Cancer.
  Bruce Montgomery, Stephen R. Plymate> ;European Urology. 2020 Feb 1
• 43 citations
  Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer
  Yingming Li, Rendong Yang, Christine Henzler, Yeung Ho, Courtney N. Passow, Benjamin Auch, Suzanne Carreira, Daniel Nava Rodrigues, Claudia Bertan, Tae Hyun Hwang, Dav...> ;Clinical Cancer Research. 2020 Apr 15
• 3 citations
  Intracrine androgen biosynthesis and drug resistance.
  Trevor M Penning, Irfan A Asangani, Cynthia Sprenger, Stephen Plymate> ;Cancer Drug Resistance. 2020 Jan 1
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Journal Articles

• Alternative Splicing in Prostate Cancer  
  Ganesh V Raj, Stephen R Plymate, Nature