StephenDSchmidtMD

PubMed

• 34 citations
  Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting.
  Cheng Cheng, Kai Xu, Rui Kong, Gwo-Yu Chuang, Angela R. Corrigan, Hui Geng, Kurt R. Hill, Alexander J. Jafari, Sijy O'Dell, Li Ou, Reda Rawi, Ariana P. Rowshan, Edward...> ;Plos One. 2019 Apr 17
• 15 citations
  Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes
  Sean P. O’Brien, Adrienne E. Swanstrom, Amarendra Pegu, Sung-Youl Ko, Taina T. Immonen, Gregory Q. Del Prete, Christine M. Fennessey, Jason Gorman, Kathryn E. Foulds, ...> ;Plos Pathogens. 2019 Apr 3
• Limited anti-HIV neutralizing antibody breadth and potency before and after HIV superinfection in Danish men who have sex with men.
  Andrew D. Redd, Marie Helleberg, Matthew Sievers, Stephen D. Schmidt, Nicole A. Doria-Rose, Daniel Bruno, Shelby Traeger, Craig Martens, Jannik Fonager, Gitte Kronborg...> ;Infectious Diseases. 2019 Jan 2
• 12 citations
  Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation
  Christina Guzzo, Peng Zhang, Qingbo Liu, Alice L. Kwon, Ferzan Uddin, Alexandra I. Wells, Hana Schmeisser, Raffaello Cimbro, Jinghe Huang, Nicole A. Doria-Rose, Stephe...> ;Mbio. 2018 Dec 11
• 43 citations
  Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody
  Young Do Kwon, Gwo-Yu Chuang, Baoshan Zhang, Robert T. Bailer, Nicole A. Doria-Rose, Tatyana Gindin, Bob C. Lin, Mark K. Louder, Krisha McKee, Sijy O'Dell, Amarendra P...> ;Cell Reports. 2018 Feb 13
• 25 citations
  Structure of an N276-dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole adjacent to the CD4 Binding Site
  Constantinos Kurt Wibmer, Jason Gorman, Colin Anthony, Nonhlanhla N. Mkhize, Aliaksandr Druz, Talita. York, Stephen D. Schmidt, Phillip. Labuschagne, Mark K. Louder, R...> ;Journal of Virology. 2016 Aug 31
• 247 citations
  A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges
  Rajeev Gautam, Yoshiaki Nishimura, Amarendra Pegu, Martha Nason, Florian Klein, Anna Gazumyan, Jovana Golijanin, Alicia Buckler-White, Reza Sadjadpour, Keyun Wang, Zac...> ;Nature. 2016 May 5
• 48 citations
  Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody
  Cheng Cheng, Marie Pancera, Adam Bossert, Stephen D. Schmidt, Rita E. Chen, Xuejun Chen, Aliaksandr Druz, Sandeep Narpala, Nicole A. Doria-Rose, Adrian B. McDermott, P...> ;Journal of Virology. 2016 Mar 15
• 61 citations
  Human Immunodeficiency Virus Type 1 Monoclonal Antibodies Suppress Acute Simian-Human Immunodeficiency Virus Viremia and Limit Seeding of Cell-Associated Viral Reservo...
  Diane L. Bolton, Amarendra Pegu, Keyun Wang, Kathleen A. McGinnis, Martha Nason, Kathryn E. Foulds, Valerie Letukas, Stephen D. Schmidt, Xuejun Chen, John Paul Todd, J...> ;Journal of Virology. 2016 Feb 1
• 14 citations
  Combination recombinant simian or chimpanzee adenoviral vectors for vaccine development
  Cheng Cheng, Lingshu Wang, Sung Youl Ko, Wing Pui Kong, Stephen D. Schmidt, Jason G. D. Gall, Stefano Colloca, Robert A. Seder, John R. Mascola, Gary J. Nabel> ;Vaccine. 2015 Dec 16
• 91 citations
  Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection
  Kevin O. Saunders, Lingshu Wang, M. Gordon Joyce, Zhi Yong Yang, Alejandro B. Balazs, Cheng Cheng, Sung Youl Ko, Wing Pui Kong, Rebecca S. Rudicell, Ivelin S. Georgiev...> ;Journal of Virology. 2015 Aug 15
• 102 citations
  Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection.
  Takuya Yamamoto, Rebecca M. Lynch, Rajeev Gautam, Rodrigo Matus-Nicodemos, Stephen D. Schmidt, Kristin L. Boswell, Sam Darko, Patrick Wong, Zizhang Sheng, Constantinos...> ;Science Translational Medicine. 2015 Jul 29
• 86 citations
  Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection
  Kevin O. Saunders, Amarendra Pegu, Ivelin S. Georgiev, Ming Zeng, M. Gordon Joyce, Zhi Yong Yang, Sung Youl Ko, Xuejun Chen, Stephen D. Schmidt, Ashley T. Haase, John ...> ;Journal of Virology. 2015 Jun 1
• 73 citations
  Analysis of immunoglobulin transcripts and hypermutation following SHIV AD8 infection and protein-plus-adjuvant immunization
  Joseph R. Francica, Zizhang Sheng, Zhenhai Zhang, Yoshiaki Nishimura, Masashi Shingai, Akshaya Ramesh, Brandon F. Keele, Stephen D. Schmidt, Barbara J. Flynn, Sam Dark...> ;Nature Communications. 2015 Apr 10
• Glacial ice and atmospheric forcing on the Mertz Glacier Polynya over the past 250 years.
  Campagne P, Crosta X, Houssais MN, Swingedouw D, Schmidt S, Martin A, Devred E, Capo S, Marieu V, Closset I, Massé G> ;Nat Commun. 2015-03-24
• Correction for Acharya et al., Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements ...
  Acharya, P.,Luongo, T. S.,Georgiev, I. S.,Matz, J.,Schmidt, S. D.,Louder, M. K.,Kessler, P.,Yang, Y.,McKee, K.,O'Dell, S.,Chen, L.,Baty, D.,Chames, P.,Martin, L.,Masco...> ;J. Virol.. 2014 Dec 18
• 219 citations
  Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo
  Rebecca S. Rudicell, Young Do Kwon, Sung-Youl Ko, Amarendra Pegu, Mark K. Louder, Ivelin S. Georgiev, Xueling Wu, Jiang Zhu, Jeffrey C. Boyington, Xuejun Chen, Wei Shi...> ;Journal of Virology. 2014 Nov 1
• 202 citations
  Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor
  Amarendra Pegu, Zhi Yong Yang, Jeffrey C. Boyington, Lan Wu, Sung Youl Ko, Stephen D. Schmidt, Krisha McKee, Wing Pui Kong, Wei Shi, Xuejun Chen, John Paul Todd, Norma...> ;Science Translational Medicine. 2014 Jul 2
• 573 citations
  Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
  Nicole A. Doria-Rose, Chaim A. Schramm, Jason Gorman, Penny L. Moore, Jinal N. Bhiman, Brandon J. DeKosky, Michael J. Ernandes, Ivelin S. Georgiev, Helen J. Kim, Marie...> ;Nature. 2014 May 1
• 120 citations
  Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV
  Mario Roederer, Brandon F. Keele, Stephen D. Schmidt, Rosemarie D. Mason, Hugh C. Welles, Will Fischer, Celia C. LaBranche, Kathryn E. Foulds, Mark K. Louder, Zhi-Yong...> ;Nature. 2014 Jan 23
• 54 citations
  Residue-Level Prediction of HIV-1 Antibody Epitopes Based on Neutralization of Diverse Viral Strains
  Gwo-Yu Chuang, Priyamvada Acharya, Stephen D. Schmidt, Yongping Yang, Mark K. Louder, Tongqing Zhou, Young Do Kwon, Marie Pancera, Robert T. Bailer, Nicole A. Doria-Ro...> ;Journal of Virology. 2013 Sep 15
• 19 citations
  Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding ...
  Priyamvada Acharya, Timothy S. Luongo, Ivelin S. Georgiev, Julie Matz, Stephen D. Schmidt, Mark K. Louder, Pascal Kessler, Yongping Yang, Krisha McKee, Sijy O'Dell, Le...> ;Journal of Virology. 2013 Sep 15
• 180 citations
  Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
  Ivelin S. Georgiev, Nicole A. Doria-Rose, Tongqing Zhou, Young Do Kwon, Ryan P. Staupe, Stephanie Moquin, Gwo-Yu Chuang, Mark K. Louder, Stephen D. Schmidt, Han Altae-...> ;Science. 2013 May 10
• 30 citations
  Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model.
  Jose Morales-Corraliza, Stephen D. Schmidt, Matthew J. Mazzella, Jason D. Berger, Donald A. Wilson, Daniel W. Wesson, Mathias Jucker, Efrat Levy, Ralph A. Nixon, Paul ...> ;Neurobiology of Aging. 2013 Jan 1
• 63 citations
  Most rhesus macaques infected with the CCR5-tropic SHIV AD8 generate cross-reactive antibodies that neutralize multiple HIV-1 strains
  Masashi Shingai, Olivia K. Donau, Stephen D. Schmidt, Rajeev Gautam, Ronald J. Plishka, Alicia Buckler-White, Reza Sadjadpour, Wendy Lee, Celia C. LaBranche, David C. ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2012 Nov 27
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