StephenIraWassermanMD

Allergy & Immunology • La Jolla, CA

Professor of Medicine, UCSD

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Office
9350 Campus Point Dr
Suite 2a
La Jolla, CA 92037
Phone+1 858-657-8322

Fax+1 858-534-7517
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Education & Training

University of California (San Diego) Medical CenterResidency, Dermatology, 1982 - 1983
Brigham and Women's HospitalResidency, Internal Medicine, 1972 - 1973
US Public Health Service HospitalResidency, Internal Medicine, 1970 - 1972
Brigham and Women's HospitalResidency, Internal Medicine, 1968 - 1970
David Geffen School of Medicine at UCLAClass of 1968

Certifications & Licensure

CA State Medical License 1969 - 2024
American Board of Allergy and Immunology Allergy & Immunology
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 1984
Fellow (FAAAAI) American Academy of Allergy Asthma and Immunology
Super Doctor SuperDoctors.com

Clinical Trials

Asthma Clinical Research Network (ACRN) Start of enrollment: 1993 Sep 01
Withdrawn
Phase 3
Asthma Clinical Research Network (ACRN) Trial - Long-Acting Beta Agonist Response by Genotype (LARGE) Start of enrollment: 2004 Dec 01
Completed
Phase 3
Asthma Clinical Research Network (ACRN) Trial - Macrolides in Asthma (MIA) Start of enrollment: 2006 Jun 01
Completed
Phase 3
Asthma Clinical Research Network (ACRN) Trial - Best Adjustment Strategy for Asthma in Long Term (BASALT) Start of enrollment: 2007 Jun 01
Completed
Phase 3
Asthma Clinical Research Network (ACRN) Trial - Tiotropium Bromide as an Alternative to Increased Inhaled Corticosteroid in Patients Inadequately Controlled on a Lower Dose of Inhaled Corticosteroid (TALC) Start of enrollment: 2008 May 01
Completed
Phase 3
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Publications & Presentations

PubMed

1 citations
A kinase inhibitor screen identifies signaling pathways regulating mucosal growth during otitis media.
Julia E. Noel, Keigo Suzukawa, Eduardo Chavez, Kwang Pak, Stephen I. Wasserman, Arwa Kurabi, Allen F. Ryan> ;Plos One. 2020 Aug 6
3 citations
Role of the PI3K/AKT pathway and PTEN in otitis media.
Hwan Ho Lee, Anthony Chin, Kwang Pak, Stephen I. Wasserman, Arwa Kurabi, Allen F. Ryan> ;Experimental Cell Research. 2020 Feb 1
13 citations
NOD1/NOD2-mediated recognition of non-typeable Haemophilus influenzae activates innate immunity during otitis media:
Jasmine Lee, Anke Leichtle, Emily Zuckerman, Kwang Pak, Meghan Spriggs, Stephen I. Wasserman, Arwa Kurabi> ;Innate Immunity. 2019 Aug 31
13 citations
Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery.
Joey P. Ting, Frances Tung, Stephen Antonysamy, Stephen I. Wasserman, Spencer B. Jones, Feiyu F. Zhang, Alfonso Espada, Howard B. Broughton, Michael J. Chalmers, Micha...> ;Plos One. 2018 Jan 12
13 citations
Otitis Media and Nasopharyngeal Colonization in ccl3-/- Mice.
Dominik Deniffel, Brian Nuyen, Kwang Pak, Keigo Suzukawa, Jun Hung, Arwa Kurabi, Stephen I. Wasserman, Allen F. Ryan> ;Infection and Immunity. 2017 Nov 1
28 citations
Obesity's effect on asthma extends to diagnostic criteria.
Njira L Lugogo, Cynthia L. Green, Noah Agada, Siyi Zhang, Susanne Meghdadpour, Run Zhou, Siyun Yang, Kevin J. Anstrom, Elliot Israel, Richard J. Martin, Robert F. Lema...> ;The Journal of Allergy and Clinical Immunology. 2018 Mar 1
3 citations
ABAI's MOC Assessment of Knowledge Program Matures: Adding Value with Continuous Learning and Assessment.
David I. Bernstein, Stephen I. Wasserman, William P. Thompson, Theodore M. Freeman> ;The Journal of Allergy and Clinical Immunology. in Practice. 2017 Jan 1
25 citations
Innate Immunity: Orchestrating Inflammation and Resolution of Otitis Media
Arwa Kurabi, Kwang Pak, Allen F. Ryan, Stephen I. Wasserman> ;Current Allergy and Asthma Reports. 2016 Jan 5
44 citations
The transcriptome of a complete episode of acute otitis media
Michelle L. Hernandez, Anke Leichtle, Kwang Pak, Nicholas J. G. Webster, Stephen I. Wasserman, Allen F. Ryan> ;BMC Genomics. 2015 Apr 3
14 citations
C-Jun N-terminal kinase (JNK) isoforms play differing roles in otitis media
William Yao, Meredith C. Frie, Jeffrey Pan, Kwang Pak, Nicholas J. G. Webster, Stephen I. Wasserman, Allen F. Ryan> ;BMC Immunology. 2014 Oct 14
Lipoxin Generation is Related to Soluble Epoxide Hydrolase Activity in Severe Asthma.
Ono, E.,Dutile, S.,Kazani, S.,Wechsler, M. E.,Yang, J.,Hammock, B.,Douda, D.,Tabet, Y.,Sirois, M.,Sirois, C.,Rizcallah, E.,Rousseau, E.,Israel, E.,Levy, B. D.,Ameredes...> ;Am. J. Respir. Crit. Care Med.. 2014 Aug 28
17 citations
A Mouse Model of Otitis Media Identifies HB-EGF as a Mediator of Inflammation-Induced Mucosal Proliferation
Keigo Suzukawa, Julia Tomlin, Kwang Pak, Eduardo Chavez, Arwa Kurabi, Andrew Baird, Stephen I. Wasserman, Allen F. Ryan> ;Plos One. 2014 Jul 17
24 citations
The inflammasome adaptor ASC contributes to multiple innate immune processes in the resolution of otitis media
Arwa Kurabi, Jasmine Lee, Chelsea Wong, Kwang Pak, Hal M. Hoffman, Allen F. Ryan, Stephen I. Wasserman> ;Innate Immunity. 2015 Feb 1
86 citations
Predictors of response to tiotropium versus salmeterol in asthmatic adults
Stephen P. Peters, Eugene R. Bleecker, Susan J. Kunselman, Nikolina Icitovic, Wendy C. Moore, Rodolfo M. Pascual, Bill T. Ameredes, Homer A. Boushey, William J. Calhou...> ;The Journal of Allergy and Clinical Immunology. 2013 Nov 1
82 citations
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients
Xingnan Li, Gregory A. Hawkins, Elizabeth J. Ampleford, Wendy C. Moore, Huashi Li, Annette T. Hastie, Timothy D. Howard, Homer A. Boushey, William W. Busse, William J....> ;The Journal of Allergy and Clinical Immunology. 2013 Aug 1
142 citations
Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized contro...
William J. Calhoun, Bill T. Ameredes, Tonya S. King, Nikolina Icitovic, Eugene R. Bleecker, Mario Castro, Reuben M. Cherniack, Vernon M. Chinchilli, Timothy J. Craig, ...> ;JAMA. 2012 Sep 12
Maintenance of certification and maintenance of professionalism.
Stephen I. Wasserman> ;The Journal of Allergy and Clinical Immunology. 2011 Sep 1
166 citations
Asthma in the Elderly: Current Understanding and Future Research Needs: A Report of a National Institute on Aging (NIA) Workshop
Nicola A. Hanania, Monroe J. King, Sidney S. Braman, Carol A. Saltoun, Robert A. Wise, Paul L. Enright, Ann R. Falsey, Sameer K. Mathur, Joe W. Ramsdell, Linda Rogers,...> ;The Journal of Allergy and Clinical Immunology. 2011 Sep 1
5 citations
Biologic modulators in allergic and autoinflammatory diseases.
Lori Broderick, Louanne M. Tourangeau, Arthur Kavanaugh, Stephen I. Wasserman> ;Current Opinion in Allergy and Clinical Immunology. 2011 Aug 1
MOC CME program.
Stephen I. Wasserman, Lawrence J. Vapniarek> ;Annals of Allergy, Asthma & Immunology. 2011 Aug 1
8 citations
The role of monoclonal antibodies in the treatment of severe asthma.
Louanne M. Tourangeau, Arthur Kavanaugh, Stephen I. Wasserman> ;Therapeutic Advances in Respiratory Disease. 2011 Mar 10
501 citations
Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma.
Yvonne J. Huang, Craig E. Nelson, Eoin L. Brodie, Todd Z. DeSantis, Marshall S. Baek, Jane Liu, Tanja Woyke, Martin Allgaier, James Bristow, Jeanine P. Wiener-Kronish,...> ;The Journal of Allergy and Clinical Immunology. 2011 Feb 1
21 citations
TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media.
Joerg Ebmeyer, Anke Leichtle, Michelle L. Hernandez, Umay Ebmeyer, Jacob Husseman, Kwang Pak, Holger Sudhoff, David H. Broide, Stephen I. Wasserman, Allen F. Ryan> ;BMC Immunology. 2011 Jan 26
34 citations
The role of DNA sensing and innate immune receptor TLR9 in otitis media
Anke Leichtle, Michelle L. Hernandez, Jasmine Lee, Kwang Pak, Nicholas J. G. Webster, Barbara Wollenberg, Stephen I. Wasserman, Allen F. Ryan> ;Innate Immunity. 2012 Feb 1
46 citations
Innate signaling in otitis media: pathogenesis and recovery.
Anke Leichtle, Yuping Lai, Barbara Wollenberg, Stephen I. Wasserman, Allen F. Ryan> ;Current Allergy and Asthma Reports. 2011 Feb 1
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Press Mentions

ABAI’s New Continuous Assessment Program Unveiled in the January/February Issue of JACI in PracticeJanuary 23rd, 2017
Lansoprazole for Children with Poorly Controlled AsthmaA Randomized Controlled TrialJanuary 25th, 2012

Grant Support

Mechanisms Of Persistence And Recovery In Otitis MediaNational Institute On Deafness And Other Communication Disorders2010–2012
Asthma Clinical Research NetworkNational Heart, Lung, And Blood Institute2003–2012
MAST Cells And Innate Immunity In Otitis MediaNational Institute On Deafness And Other Communication Disorders2003–2007
Efficacy Of Immunotherapy In Mite Allergic AsthmaNational Institute Of Allergy And Infectious Diseases1985–1989
Release &Effect Of MAST Cell/Basophil MediatorsNational Institute Of Allergy And Infectious Diseases1986–1988
Atopic DermatitisNational Institute Of Allergy And Infectious Diseases1985
Role Of The MAST Cell In Intestinal Immune FunctionNat Inst Of Arthritis, Diabetes, Digestive &Kidney Diseases1985