StevenMOpalMD

PubMed

• Antimicrobial Efficacy of Continuous Low-Irradiance Phototherapy Against Multidrug-Resistant Organisms.
  Patrick McMullan, Alexander B White, Oluwadara Coker, Steven Opal, Shayan A McGee, Gary Rogers> ;Photobiomodulation, Photomedicine, and Laser Surgery. 2022 Sep 1
• 2 citations
  A pilot study of an anti-endotoxin Ig-enriched bovine colostrum to prevent experimental sepsis:
  Alan S. Cross, Steven M. Opal, John E. Palardy, Surekha Shridhar, Scott M Baliban, Alison J. Scott, Abdullah Chahin, Robert K. Ernst> ;Innate Immunity. 2021 Apr 16
• 14 citations
  Therapeutic Rationale for Endotoxin Removal with Polymyxin B Immobilized Fiber Column (PMX) for Septic Shock.
  Hisataka Shoji, Steven M. Opal> ;International Journal of Molecular Sciences. 2021 Feb 23
• 16 citations
  Steroids for sepsis and ARDS: this eternal controversy remains with COVID-19.
  Jean Carlet, Didier Payen, Steven M. Opal> ;Lancet. 2020 Oct 9
• 5 citations
  Safety and Pharmacokinetics of Recombinant Human Plasma Gelsolin in Patients Hospitalized for Nonsevere Community-Acquired Pneumonia.
  Abla Tannous, Susan L Levinson, James Bolognese, Steven M. Opal, Mark J. DiNubile> ;Antimicrobial Agents and Chemotherapy. 2020 Sep 21
• Reply to Siniorakis et al., "COVID-19 Interference with Renin-Angiotensin System in the Context of Heart Failure".
  David S. Fedson, Steven M. Opal, Ole Martin Rordam> ;Mbio. 2020 Jun 30
• 41 citations
  Activating Immunity to Fight a Foe - A New Path.
  Richard S. Hotchkiss, Steven M. Opal> ;The New England Journal of Medicine. 2020 Mar 25
• 106 citations
  Hiding in Plain Sight: an Approach to Treating Patients with Severe COVID-19 Infection
  David S. Fedson, Steven M. Opal, Ole Martin Rordam> ;Mbio. 2020 Apr 28
• 46 citations
  Biomarkers of Infection and Sepsis.
  Steven M. Opal, Xavier Wittebole> ;Critical Care Clinics. 2020 Jan 1
• 73 citations
  Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial.
  Pierre-François Laterre, Scott M. Berry, Allan Blemings, Jan E. Carlsen, Bruno François, Todd Graves, Karsten Jacobsen, Roger J. Lewis, Steven M. Opal, Anders Perner, ...> ;JAMA. 2019 Oct 15
• 1 citations
  Should we continue to test soluble thrombomodulin, or other systemic anticoagulants, as a life-saving therapy for sepsis-induced coagulopathy?
  Pierre-François Laterre, Mitchell M. Levy, Xavier Wittebole, T. Dugernier, Bruno François, Steven M. Opal> ;Anaesthesia, Critical Care & Pain Medicine. 2019 Oct 1
• 22 citations
  An Integrated Safety Summary of Omadacycline, a Novel Aminomethylcycline Antibiotic.
  Steven M. Opal, Thomas M. File, Tom van der Poll, Evan Tzanis, Surya Chitra, Paul C. McGovern> ;Clinical Infectious Diseases. 2019 Aug 1
• 174 citations
  Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.
  Jean Louis Vincent, Bruno François, I.B. Zabolotskikh, Mradul Kumar Daga, Jean-Baptiste Lascarrou, Mikhail Y. Kirov, Ville Pettilä, Xavier Wittebole, Ferhat Meziani, E...> ;JAMA. 2019 May 28
• 599 citations
  Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis.
  Christopher W. Seymour, Jason Kennedy, Shu Wang, Chung-Chou H. Chang, Corrine F. Elliott, Zhongying Xu, Scott M. Berry, Gilles Clermont, Gregory F. Cooper, Hernando Go...> ;JAMA. 2019 May 28
• 24 citations
  Inter-α-inhibitor Ameliorates Endothelial Inflammation in Sepsis
  Vandy P. Stober, Yow-Pin Lim, Steven M. Opal, Lisheng Zhuo, Koji Kimata, Stavros Garantziotis> ;Lung. 2019 Apr 26
• 19 citations
  Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis
  Pragnya Das, Santosh Panda, Beamon Agarwal, Sumita Behera, Syed Mohd Ali, Mark Pulse, Joseph S. Solomkin, Steven M. Opal, Vineet Bhandari, Suchismita Acharya> ;Scientific Reports. 2019 Feb 27
• 18 citations
  Physician agreement on the diagnosis of sepsis in the intensive care unit: estimation of concordance and analysis of underlying factors in a multicenter cohort
  Bert K. Lopansri, Russell R. Miller, John P. Burke, Mitchell M. Levy, Steven M. Opal, Richard E. Rothman, Franco R. D'Alessio, Venkataramana K. Sidhaye, Robert A. Balk...> ;Journal of Intensive Care. 2019 Feb 21
• 89 citations
  Towards precision medicine in sepsis: a position paper from the European Society of Clinical Microbiology and Infectious Diseases
  Jordi Rello, T.S.R. van Engelen, Emine Alp, Thierry Calandra, V. Cattoir, Winfried V. Kern, Mihai G. Netea, Saad Nseir, Steven M. Opal, F.L. van de Veerdonk, Mark H. W...> ;Clinical Microbiology and Infection. 2018 Dec 1
• 4 citations
  Coinfection With Influenza A Virus and Klebsiella oxytoca : An Underrecognized Impact on Host Resistance and Tolerance to Pulmonary Infections.
  Kayla M. Lee, Jenna Morris-Love, Damien J. Cabral, Peter Belenky, Steven M. Opal, Amanda M. Jamieson> ;Frontiers in Immunology. 2018 Oct 29
• 18 citations
  Whatever happened to the Shwartzman phenomenon
  Abdullah Chahin, Jason M. Opal, Steven M. Opal> ;Innate Immunity. 2018 Nov 8
• 23 citations
  Antibiotic Stewardship: Strategies to Minimize Antibiotic Resistance While Maximizing Antibiotic Effectiveness.
  Cheston B. Cunha, Steven M. Opal> ;The Medical Clinics of North America. 2018 Sep 1
• 9 citations
  Soluble programmed cell death protein-1 and programmed cell death ligand-1 in sepsis.
  Debasree Banerjee, Sean F. Monaghan, Runping Zhao, Thomas Walsh, Amy Palmisciano, Gary Phillips, Steven M. Opal, Mitchell M. Levy> ;Critical Care. 2018 Jun 7
• 82 citations
  Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, dou...
  Tobias Welte, R. Phillip Dellinger, Henning Ebelt, Miguel Ferrer, Steven M. Opal, Mervyn Singer, Jean Louis Vincent, Karl Werdan, Ignacio Martin-Loeches, Jordi Almiral...> ;Intensive Care Medicine. 2018 Apr 9
• 60 citations
  Validation of a Host Response Assay, SeptiCyte LAB, for Discriminating Sepsis from Systemic Inflammatory Response Syndrome in the ICU.
  Russell R. Miller, Bert K. Lopansri, John P. Burke, Mitchell M. Levy, Steven M. Opal, Richard E. Rothman, Franco R. D'Alessio, Venkataramana K. Sidhaye, Neil R. Aggarw...> ;American Journal of Respiratory and Critical Care Medicine. 2018 Oct 1
• 30 citations
  Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock—Adap...
  Roger J. Lewis, Derek C. Angus, Pierre-François Laterre, Anne Louise Kjølbye, Egbert van der Meulen, Allan Blemings, Todd Graves, James A. Russell, Jan E. Carlsen, Kar...> ;Annals of the American Thoracic Society. 2018 Feb 1
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