StevenR.SchneiderMD

PubMed

• 11 citations
  1-((3S,4S)-4-amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetes.
  Kim M. Andrews, David A. Beebe, John William Benbow, David A. Boyer, Shawn D. Doran, Yu Hui, Shenping Liu, R. Kirk McPherson, Constantin Neagu, Janice C. Parker, David...> ;Bioorganic & Medicinal Chemistry Letters. 2011 Mar 15
• Discovery of 2-(2-chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-f][1,4]oxazepin-8(5H)-one (PF-514273), a novel, bicyclic lactam-b...
  Dow, R.L., Carpino, P.A., Hadcock, J.R., Black, S.C., Iredale, P.A., DaSilva-Jardine, P., Schneider, S.R., Paight, E.S., Griffith, D.A., Scott, D.O., O'Connor, R.E., N...> ;J Med Chem. 2009-05-14
• Potent and selective, sulfamide-based human beta 3-adrenergic receptor agonists.
  Dow, R. L., Paight, E. S., Schneider, S. R., Hadcock, J. R., Hargrove, D. M., Martin, K. A., Maurer, T. S., Nardone, N. A., Tess, D. A., DaSilva-Jardine, P.> ;Bioorg Med Chem Lett. 2004 Jun 21
• Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics.
  Dow, R. L., Schneider, S. R., Paight, E. S., Hank, R. F., Chiang, P., Cornelius, P., Lee, E., Newsome, W. P., Swick, A. G., Spitzer, J., Hargrove, D. M., Patterson, T....> ;Bioorg Med Chem Lett. 2003 Feb 10
• Bioisosteric replacement of the hydrazide pharmacophore of the cannabinoid-1 receptor antagonist SR141716A. Part I: potent, orally-active 1,4-disubstituted imidazoles.
  Dow, R. L., Hadcock, J. R., Scott, D. O., Schneider, S. R., Paight, E. S., Iredale, P. A., Carpino, P. A., Griffith, D. A., Hammond, M., Dasilva-Jardine, P.> ;Bioorg Med Chem Lett. 2009 Sep 15
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