StevenYoungMD

PubMed

• 45 citations
  Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells.
  Fang Hao, Qinhong Xu, Yinglan Zhao, Jan V. Stevens, Steven H. Young, James Sinnett-Smith, Enrique Rozengurt> ;Molecular Cancer Research. 2017 Jul 1
• 6 citations
  Direct growth-inhibitory effects of prostaglandin E2 in pancreatic cancer cells in vitro through an EP4/PKA-mediated mechanism.
  Andrea I. Schmidt, James Sinnett-Smith, Steven H. Young, Hui-Hua Chang, O. Joe Hines, David W. Dawson, Enrique Rozengurt, Guido Eibl> ;Surgery. 2017 Jun 1
• 17 citations
  Hepatic porphyria: A narrative review
  Sumant Arora, Sudha Kodali, Ashwani K. Singal> ;Indian Journal of Gastroenterology. 2016 Oct 31
• Introduction: Reproductive immunology: checkered past and bright future.
  Young, S. L.> ;Fertil. Steril.. 2016 Aug 02
• Budesonide Use and Hospitalization Rate in Crohn’s Disease: Results From a Cohort at a Tertiary Care IBD Referral Center
  Jordan Orr, Krishna Venkata, Fenglong Xie, Talha A. Malik> ;Journal of Clinical Medicine Research. 2016 Aug 29
• 31 citations
  Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelia...
  Jia Wang, James Sinnett-Smith, Jan V. Stevens, Steven H. Young, Enrique Rozengurt> ;The Journal of Biological Chemistry. 2016 Aug 19
• 10 citations
  Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552.
  Jia Wang, Liang Han, James Sinnett-Smith, Li-Li Han, Jan V. Stevens, Nora Rozengurt, Steven H. Young, Enrique Rozengurt> ;American Journal of Physiology. Cell Physiology. 2016 Apr 1
• 21 citations
  Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1.
  Hui-Hua Chang, Steven H. Young, James Sinnett-Smith, Caroline Ei Ne Chou, Aune Moro, Kathleen M. Hertzer, Oscar J. Hines, Enrique Rozengurt, Guido Eibl> ;American Journal of Physiology. Cell Physiology. 2015 Nov 15
• 2 citations
  Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the ...
  Steven H. Young, Osvaldo Rey, Enrique Rozengurt> ;Biochemical and Biophysical Research Communications. 2015 Nov 6
• 74 citations
  Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2
  Heloisa P. Soares, Ming Ming, Michelle Mellon, Steven H. Young, Liang Han, James Sinnet-Smith, Enrique Rozengurt> ;Molecular Cancer Therapeutics. 2015 Feb 11
• 55 citations
  Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells.
  Ming Ming, James Sinnett-Smith, Jia Wang, Heloisa P. Soares, Steven H. Young, Guido Eibl, Enrique Rozengurt> ;Plos One. 2014 Dec 10
• 30 citations
  Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling.
  James Sinnett-Smith, Yang Ni, Jia Wang, Ming Ming, Steven H. Young, Enrique Rozengurt> ;American Journal of Physiology. Cell Physiology. 2014 May 15
• 12 citations
  Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888.
  Steven H. Young, Osvaldo Rey, James Sinnett-Smith, Enrique Rozengurt> ;American Journal of Physiology. Cell Physiology. 2014 Feb 1
• 12 citations
  Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells
  Steven H. Young, Nora Rozengurt, James Sinnett-Smith, Enrique Rozengurt> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2012 Aug 1
• 17 citations
  Crosstalk between insulin receptor and G protein-coupled receptor signaling systems leads to Ca2+ oscillations in pancreatic cancer PANC-1 cells ☆
  Steven H. Young, Enrique Rozengurt> ;Biochemical and Biophysical Research Communications. 2010 Oct 8
• 24 citations
  Amino acid sensing by enteroendocrine STC-1 cells: role of the Na+-coupled neutral amino acid transporter 2
  Steven H. Young, Osvaldo Rey, Catia Sternini, Enrique Rozengurt> ;American Journal of Physiology. Cell Physiology. 2010 Mar 10
• 54 citations
  Protein Kinase D Mediates Mitogenic Signaling by Gq-coupled Receptors through Protein Kinase C-independent Regulation of Activation Loop Ser744 and Ser748 Phosphorylation
  James Sinnett-Smith, Rodrigo Jacamo, Robert K. Kui, Yun Zu M. Wang, Steven H. Young, Osvaldo Rey, Richard T. Waldron, Enrique Rozengurt> ;The Journal of Biological Chemistry. 2009 May 15
• 37 citations
  Qdot nanocrystal conjugates conjugated to bombesin or ANG II label the cognate G protein-coupled receptor in living cells.
  Steven H. Young, Enrique Rozengurt> ;American Journal of Physiology. Cell Physiology. 2006 Mar 1
• 69 citations
  Amino acids and Ca2+ stimulate different patterns of Ca2+ oscillations through the Ca2+-sensing receptor
  Steven H. Young, Enrique Rozengurt> ;American Journal of Physiology. Cell Physiology. 2002 Jun 1
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