StuartJFrankMD

Endocrinology • Birmingham, AL

Diabetes, Lipid Metabolism

Professor, Medicine, University of Alabama School of Medicine

Join to view full profile

Dr. Frank is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Frank's full profile

Already have an account?

Office
619 19th St S
Birmingham, AL 35249
Phone+1 205-934-6600
Is this information wrong?

Summary

Division Director

Education & Training

National Institutes of Health Clinical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1989 - 1991
Washington University/B-JH/SLCH ConsortiumResidency, Internal Medicine, 1984 - 1987
Harvard Medical SchoolClass of 1984

Certifications & Licensure

AL State Medical License 1991 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Publications & Presentations

PubMed

5 citations
Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology.
Sobuj Mia, Ravi Sonkar, Lamario Williams, Mary N Latimer, David R Rawnsley, Samir Rana, Jin He, Pieterjan Dierickx, Teayoun Kim, Min Xie, Kirk M Habegger, Masato Kubo,...> ;JACC. Basic to Translational Science. 2023 Sep 1
2 citations
Identification of growth hormone receptor as a relevant target for precision medicine in low-EGFR expressing glioblastoma.
Maïté Verreault, Irma Segoviano Vilchis, Shai Rosenberg, Nolwenn Lemaire, Charlotte Schmitt, Jérémy Guehennec, Louis Royer-Perron, Jean-Léon Thomas, TuKiet T Lam, Flor...> ;Clinical and Translational Medicine. 2022 Jul 1
5 citations
Augmented Cardiac Growth Hormone Signaling Contributes to Cardiomyopathy Following Genetic Disruption of the Cardiomyocyte Circadian Clock.
Ravi Sonkar, Ryan Berry, Mary N Latimer, Sumanth D Prabhu, Martin E Young, Stuart J Frank> ;Frontiers in Pharmacology. 2022 Jan 1
3 citations
Very Low Vitamin D in a Patient With a Novel Pathogenic Variant in the GC Gene That Encodes Vitamin D-Binding Protein.
Ronadip R. Banerjee, Tara Spence, Stuart J. Frank, Raj Pandian, Andrew N. Hoofnagle, Bob Argiropoulos, Julien Marcadier> ;Journal of the Endocrine Society. 2021 Jun 5
26 citations
Branched chain amino acids selectively promote cardiac growth at the end of the awake period.
Mary N. Latimer, Ravi Sonkar, Sobuj Mia, Isabelle Robillard Frayne, Karen J. Carter, Christopher A. Johnson, Samir Rana, Min Xie, Glenn C. Rowe, Adam R. Wende, Sumanth...> ;Journal of Molecular and Cellular Cardiology. 2021 Apr 21
9 citations
Impact of obesity on day-night differences in cardiac metabolism.
Sobuj Mia, Ravi Sonkar, Lamario Williams, Mary N. Latimer, Isabelle Frayne Robillard, Abhinav Diwan, Stuart J. Frank, Christine Des Rosiers, Martin E. Young> ;FASEB Journal. 2021 Mar 1
1 citations
Physiology of GH action and associated human disorders.
Horacio M. Domené, Jan M. Wit, Stuart J. Frank> ;Molecular and Cellular Endocrinology. 2021 Jan 15
13 citations
Classical and novel GH receptor signaling pathways.
Stuart J. Frank> ;Molecular and Cellular Endocrinology. 2020 Dec 1
11 citations
A Small Molecule, UAB126, Reverses Diet-Induced Obesity and its Associated Metabolic Disorders.
Guang Ren, Teayoun Kim, Hae-Suk Kim, Martin E. Young, Donald D. Muccio, Venkatram R. Atigadda, Samuel I. Blum, Hubert M. Tse, Kirk M. Habegger, Sushant Bhatnagar, Tatj...> ;Diabetes. 2020 Jul 1
27 citations
Differential effects of REV-ERBα/β agonism on cardiac gene expression, metabolism, and contractile function in a mouse model of circadian disruption.
Sobuj Mia, Mariame Selma Kane, Mary N. Latimer, Cristine J. Reitz, Ravi Sonkar, Gloria A. Benavides, Samuel R. Smith, Stuart J. Frank, Tami A. Martino, Jianhua Zhang, ...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2020 Jun 1
73 citations
Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity.
Daniel DiToro, Stacey N. Harbour, Jennifer K. Bando, Gloria A. Benavides, Steven Witte, Vincent A. Laufer, Carson E. Moseley, Jeffery R. Singer, Blake Frey, Henrietta ...> ;Immunity. 2020 Apr 14
4 citations
Autocrine/paracrine actions of growth hormone in human melanoma cell lines.
Ashiya Buckels, Yue Zhang, Jing Jiang, Mohammad Athar, Farrukh Afaq, Lalita Shevde-Samant, Stuart J. Frank> ;Biochemistry and Biophysics Reports. 2020 Mar 1
6 citations
Growth hormone (GH) receptor (GHR)-specific inhibition of GH-Induced signaling by soluble IGF-1 receptor (sol IGF-1R).
Yue Zhang, Sajina Gc, Sweta B. Patel, Ying Liu, Andrew J. Paterson, John C. Kappes, Jing Jiang, Stuart J. Frank> ;Molecular and Cellular Endocrinology. 2019 Jul 15
3 citations
Moving Career Development Upstream: Evaluation of a Course for Internal Medicine Trainees Contemplating Career Pathways in Academic Medicine.
Ryan R. Kraemer, Jessica F. Wakelee, Lisle Hites, Stuart J. Frank, Kenneth G. Saag, David A. Rogers, Anoma Nellore, Nathan Erdmann, Ashley Nichols, Jessica S. Merlin> ;Southern Medical Journal. 2018 Aug 1
6 citations
Differential tissue response to growth hormone in mice.
Ryan Berry, Graham R. McGinnis, Ronadip R. Banerjee, Martin E. Young, Stuart J. Frank> ;FEBS Open Bio. 2018 Jul 1
13 citations
Temporal partitioning of adaptive responses of the murine heart to fasting.
Rachel A. Brewer, Helen E. Collins, Ryan Berry, Manoja K. Brahma, Brian A. Tirado, Rodrigo A. Peliciari-Garcia, Haley L. Stanley, Adam R. Wende, Heinrich Taegtmeyer, N...> ;Life Sciences. 2018 Mar 15
32 citations
Effects of rapamycin on growth hormone receptor knockout mice.
Yimin Fang, Cristal M. Hill, Justin Darcy, Adriana Reyes-Ordoñez, Edwin Arauz, Samuel McFadden, Chi Zhang, Jared M. Osland, John Gao, Tian Zhang, Stuart J. Frank, Mart...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb 13
10 citations
Subdomain 2, Not the Transmembrane Domain, Determines the Dimerization Partner of Growth Hormone Receptor and Prolactin Receptor.
Ying Liu, Jing Jiang, Bradford Lepik, Yue Zhang, Kurt R. Zinn, Stuart J. Frank> ;Endocrinology. 2017 Oct 1
47 citations
Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart.
Graham R. McGinnis, Yawen Tang, Rachel A. Brewer, Manoja K. Brahma, Haley L. Stanley, Gobinath Shanmugam, Namakkal S. Rajasekaran, Glenn C. Rowe, Stuart J. Frank, Adam...> ;Journal of Molecular and Cellular Cardiology. 2017 Sep 1
8 citations
Molecular interactions of EphA4, growth hormone receptor, Janus kinase 2, and signal transducer and activator of transcription 5B.
Takahiro Sawada, Daiki Arai, Xuefeng Jing, Masayasu Miyajima, Stuart J. Frank, Kazushige Sakaguchi> ;Plos One. 2017 Jul 7
11 citations
Insulin, IGF-1, and GH Receptors Are Altered in an Adipose Tissue Depot-Specific Manner in Male Mice With Modified GH Action.
Rikke Hjortebjerg, Darlene E. Berryman, Ross Comisford, Stuart J. Frank, Edward O. List, Mette Bjerre, Jan Frystyk, John J. Kopchick> ;Endocrinology. 2017 May 1
Use of MRI in Low-Dose-Rate and High-Dose-Rate Prostate Brachytherapy from Diagnosis to Treatment Assessment: Defining the Knowledge Gaps, Technical Challenges, and Ba...
Stuart Frank, MD> ;Brachytherapy.
37 citations
Calcium channel blocker use is associated with lower fasting serum glucose among adults with diabetes from the REGARDS study
Yulia Khodneva, Anath Shalev, Stuart J. Frank, April P. Carson, Monika M. Safford> ;Diabetes Research and Clinical Practice. 2016 May 1
9 citations
TIMP3 Modulates GHR Abundance and GH Sensitivity.
Yue Zhang, Xiangdong Wang, Kimberly Loesch, Larry A. May, George E. Davis, Jing Jiang, Stuart J. Frank> ;Molecular Endocrinology. 2016 Apr 13
11 citations
GHR/PRLR Heteromultimer Is Composed of GHR Homodimers and PRLR Homodimers
Ying Liu, Yue Zhang, Jing Jiang, Peter E. Lobie, Ramasamy Paulmurugan, John F. Langenheim, Wen Y. Chen, Kurt R. Zinn, Stuart J. Frank> ;Molecular Endocrinology. 2016 Mar 22
Join now to see all

Journal Articles

Effects of Rapamycin on Growth Hormone Receptor Knockout Mice
Stuart J Frank, Proceedings of the National Academy of Sciences

Grant Support

Growth Hormone Receptor Dimerization &Disulfide LinkageNational Institute Of Diabetes And Digestive And Kidney Diseases2011–2012
Tyrosine Phosphorylation And Growth Hormone SignalingNational Institute Of Diabetes And Digestive And Kidney Diseases1997–2011
Growth Hormone Receptor Dimerization/Disulfide LinkageNational Institute Of Diabetes And Digestive And Kidney Diseases2010
"Growth Hormone Receptor Dimerization/Disulfide Linkage"National Institute Of Diabetes And Digestive And Kidney Diseases2007–2010
Growth Hormone Receptor Dimerization/Disulfide LinkageNational Institute Of Diabetes And Digestive And Kidney Diseases2001–2006
Tyrosine Phosphyorylation And Growth Hormone SignalingNational Institute Of Diabetes And Digestive And Kidney Diseases2005
Tyrosine Phosphorylation And Growth Hormone SignallingNational Institute Of Diabetes And Digestive And Kidney Diseases2001–2004
Tyrosine Phosphorylation And Growth Hormone SignalingNational Institute Of Diabetes And Digestive And Kidney Diseases1993–1996

Hospital Affiliations

Birmingham VA Medical CenterBirmingham, Alabama
University of Alabama HospitalBirmingham, Alabama