SumitAroraMD

PubMed

• 8 citations
  Evaluating the impact of acid-reducing agents on drug absorption using biorelevant in vitro tools and PBPK modeling - case example dipyridamole.
  Domagoj Segregur, Richard Barker, James Mann, Andrea Moir, Eva Karlsson, David B. Turner, Sumit Arora, Jennifer B. Dressman> ;European Journal of Pharmaceutical Sciences. 2021 May 1
• 17 citations
  On Absorption Modeling and Food Effect Prediction of Rivaroxaban, a BCS II Drug Orally Administered as an Immediate-Release Tablet
  Varun Kushwah, Sumit Arora, Miklós Tamás Katona, Dattatray Modhave, Eleonore Fröhlich, Amrit Paudel> ;Pharmaceutics. 2021 Feb 20
• 17 citations
  Physiologically Based Pharmacokinetic Modeling of Transdermal Selegiline and Its Metabolites for the Evaluation of Disposition Differences between Healthy and Special ...
  Santosh Kumar Puttrevu, Sumit Arora, Sebastian Polak, Nikunjkumar Patel> ;Pharmaceutics. 2020 Sep 30
• 13 citations
  Biorelevant Two-Stage In Vitro Testing for rDCS Classification and in PBPK Modeling-Case Example Ritonavir.
  Tom Fiolka, Jens Van Den Abeele, Patrick Augustijns, Sumit Arora, Jennifer B. Dressman> ;Journal of Pharmaceutical Sciences. 2020 Aug 1
• Electrocuted Hip: Late Consequences of Electrical Shock Injuries of Orthopaedic Relevance: A Case Report and Review of Literature.
  Yasim Khan, Sumit Arora, Swati Gupta, Nidhi Mahajan, Sumit Sural, Anil Dhal> ;JBJS Case Connector. 2020 Jul 1
• 16 citations
  Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed Physiologically-Based Pharmacokinetic Model of Ritonavir Norvir Tablet Absorption in Humans Under Fast...
  Sumit Arora, Amita Pansari, Peter Kilford, Masoud Jamei, Iain Gardner, David B. Turner> ;Molecular Pharmaceutics. 2020 Jun 1
• 30 citations
  Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer.
  Mohammad Aslam Khan, Sanjeev K. Srivastava, Haseeb Zubair, Girijesh Kumar Patel, Sumit Arora, Moh’d Khushman, James E. Carter, Gregory S. Gorman, Seema Singh, Ajay P. ...> ;The Journal of Biological Chemistry. 2020 Jun 19
• 17 citations
  Use of PBPK Modeling To Evaluate the Performance of Dissolv It, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products
  Mireille Hassoun, Maria Malmlöf, Otto Scheibelhofer, Abhinav Kumar, Sukhi Bansal, Ewa Selg, Mattias Nowenwik, Per Gerde, Snezana Radivojev, Amrit Paudel, Sumit Arora, ...> ;Molecular Pharmaceutics. 2019 Mar 4
• 44 citations
  Advances in experimental and mechanistic computational models to understand pulmonary exposure to inhaled drugs.
  Per Bäckman, Sumit Arora, William Couet, Ben Forbes, Wilbur de Kruijf, Amrit Paudel> ;European Journal of Pharmaceutical Sciences. 2017 Oct 25
• 10 citations
  Formulation, optimization, and in vitro–in vivo evaluation of olmesartan medoxomil nanocrystals
  Sanyog Jain, Kamlesh Patel, Sumit Arora, Venkata Appa Reddy, Chander Parkash Dora> ;Drug Delivery and Translational Research. 2017 Jan 23
• 26 citations
  Glucose Metabolism Reprogrammed by Overexpression of IKKε Promotes Pancreatic Tumor Growth.
  Haseeb Zubair, Shafquat Azim, Sanjeev K. Srivastava, Aamir Ahmad, Arun Bhardwaj, Mohammad Aslam Khan, Girijesh Kumar Patel, Sumit Arora, James E. Carter, Seema Singh, ...> ;Cancer Research. 2016 Dec 15
• 44 citations
  Comparative analysis of the relative potential of silver, Zinc-oxide and titanium-dioxide nanoparticles against UVB-induced DNA damage for the prevention of skin carci...
  Nikhil Tyagi, Sanjeev K. Srivastava, Sumit Arora, Yousef Omar, Ahmed Al-Ghadhban, Sachin Kumar Deshmukh, James E. Carter, Ajay P. Singh, Seema Singh, Zohaib Mohammad Ijaz> ;Cancer Letters. 2016 Dec 1
• 24 citations
  Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk.
  Courey Averett, Arun Bhardwaj, Sumit Arora, Sanjeev K. Srivastava, Mohammad Aslam Khan, Aamir Ahmad, Seema Singh, James E. Carter, Moh’d Khushman, Ajay P. Singh> ;Carcinogenesis. 2016 Nov 1
• 17 citations
  MYB Promotes Desmoplasia in Pancreatic Cancer through Direct Transcriptional Up-regulation and Cooperative Action of Sonic Hedgehog and Adrenomedullin.
  Arun Bhardwaj, Sanjeev K. Srivastava, Seema Singh, Nikhil Tyagi, Sumit Arora, James E. Carter, Moh’d Khushman, Ajay P. Singh> ;The Journal of Biological Chemistry. 2016 Jul 29
• 11 citations
  Development of surface stabilized candesartan cilexetil nanocrystals with enhanced dissolution rate, permeation rate across CaCo-2, and oral bioavailability
  Sanyog Jain, Venkata Appa Reddy, Sumit Arora, Kamlesh Patel> ;Drug Delivery and Translational Research. 2016 Apr 29
• 23 citations
  Highly respirable dry powder inhalable formulation of voriconazole with enhanced pulmonary bioavailability.
  Sumit Arora, Mehra Haghi, Paul M. Young, Michael Kappl, Daniela Traini, Sanyog Jain> ;Expert Opinion on Drug Delivery. 2016 Jan 1
• 42 citations
  Exploiting Nanotechnology for the Development of MicroRNA-Based Cancer Therapeutics.
  Nikhil Tyagi, Sumit Arora, Sachin Kumar Deshmukh, Seema Singh, Saravanakumar Marimuthu, Ajay P. Singh> ;Journal of Biomedical Nanotechnology. 2016 Jan 1
• 38 citations
  MYB is a novel regulator of pancreatic tumour growth and metastasis
  Sanjeev K. Srivastava, Arun Bhardwaj, Sumit Arora, Seema Singh, Shafquat Azim, Nikhil Tyagi, James E. Carter, Bin Wang, Ajay P. Singh> ;British Journal of Cancer. 2015 Dec 22
• 36 citations
  In vivo prediction of CYP-mediated metabolic interaction potential of formononetin and biochanin A using in vitro human and rat CYP450 inhibition data
  Sumit Arora, Isha Taneja, Muralikrishna Challagundla, Kanumuri Siva Rama Raju, Sheelendra Pratap Singh, Muhammad Wahajuddin> ;Toxicology Letters. 2015 Nov 19
• 17 citations
  Size is an essential parameter in governing the UVB-protective efficacy of silver nanoparticles in human keratinocytes.
  Rohan Palanki, Sumit Arora, Nikhil Tyagi, Lilia Rusu, Ajay P. Singh, Srinivas Palanki, James E. Carter, Seema Singh> ;BMC Cancer. 2015 Sep 15
• 27 citations
  Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin Carcinogenesis
  Nikhil Tyagi, Arun Bhardwaj, Sanjeev K. Srivastava, Sumit Arora, Saravanakumar Marimuthu, Sachin Kumar Deshmukh, Ajay P. Singh, James E. Carter, Seema Singh> ;Scientific Reports. 2015 Sep 9
• 51 citations
  MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways.
  Sanjeev K. Srivastava, Arun Bhardwaj, Sumit Arora, Nikhil Tyagi, Seema Singh, Joel Andrews, Steve McClellan, Bin Wang, Ajay P. Singh> ;British Journal of Cancer. 2015 Aug 11
• 45 citations
  Silver nanoparticles protect human keratinocytes against UVB radiation-induced DNA damage and apoptosis: potential for prevention of skin carcinogenesis.
  Sumit Arora, Nikhil Tyagi, Arun Bhardwaj, Lilia Rusu, Rohan Palanki, Komal Vig, Shree R. Singh, Ajay P. Singh, Srinivas Palanki, Michael E. Miller, James E. Carter, Se...> ;Nanomedicine. 2015 Jul 1
• 41 citations
  Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis
  Sanjeev K. Srivastava, Arun Bhardwaj, Sumit Arora, Nikhil Tyagi, Ajay P. Singh, James E. Carter, Jonathan G. Scammell, Øystein Fodstad, Seema Singh> ;British Journal of Cancer. 2015 May 26
• 27 citations
  Development of an inhaled controlled release voriconazole dry powder formulation for the treatment of respiratory fungal infection.
  Sumit Arora, Mehra Haghi, Ching-Yee Loo, Daniela Traini, Paul M. Young, Sanyog Jain> ;Molecular Pharmaceutics. 2015 May 7
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