SunilSudhirRaikarMD

PubMed

• Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia.
  Hope L Mumme, Sunil S Raikar, Swati S Bhasin, Beena E Thomas, Taylor Lawrence, Elizabeth P Weinzierl, Yakun Pang, Deborah DeRyckere, Chuck Gawad, Daniel S Wechsler, Ch...> ;Genome Medicine. 2023 Oct 16
• Development of a microfluidic cell transfection device into gene-edited CAR T cell manufacturing workflow.
  Tong Yu, Navdeep Jhita, Peter Shankles, Andrew Fedanov, Noah Kramer, Sunil S Raikar, Todd Sulchek> ;Lab on a Chip. 2023 Nov 7
• 2 citations
  Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia.
  Hope Mumme, Beena E Thomas, Swati S Bhasin, Upaasana Krishnan, Bhakti Dwivedi, Pruthvi Perumalla, Debasree Sarkar, Gulay B Ulukaya, Himalee S Sabnis, Sunita I Park, De...> ;Nature Communications. 2023 Oct 5
• 1 citations
  Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis.
  Swati S Bhasin, Beena E Thomas, Ryan J Summers, Debasree Sarkar, Hope Mumme, William Pilcher, Mohamed Emam, Sunil S Raikar, Sunita I Park, Sharon M Castellino, Douglas...> ;Scientific Reports. 2023 Aug 2
• 4 citations
  Enhancing the effectiveness of γδ T cells by mRNA transfection of chimeric antigen receptors or bispecific T cell engagers.
  Scott A Becker, Brian G Petrich, Bing Yu, Kristopher A Knight, Harrison C Brown, Sunil S Raikar, Christopher B Doering, H Trent Spencer> ;Molecular Therapy Oncolytics. 2023 Jun 15
• Multicolor Light-Induced Immune Activation via Polymer Photocaged Cytokines.
  Lacey A Birnbaum, Emily C Sullivan, Priscilla Do, Biaggio Uricoli, Sunil S Raikar, Christopher C Porter, Curtis J Henry, Erik C Dreaden> ;Biomacromolecules. 2023 Mar 13
• 11 citations
  Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.
  Miyoung Lee, Jamie A G Hamilton, Ganesh R Talekar, Anthony J Ross, Langston Michael, Manali Rupji, Bhakti Dwivedi, Sunil S Raikar, Jeremy Boss, Christopher D Scharer, ...> ;Nature Communications. 2022 Mar 3
• 10 citations
  Allogeneic gamma delta T cells as adoptive cellular therapy for hematologic malignancies.
  Navdeep Jhita, Sunil S Raikar> ;Exploration of Immunology. 2022 Jan 1
• Cryptic t(6;11) KMT2A rearrangement in a pediatric acute myeloid leukemia patient detected by next-generation sequencing and dual-fusion FISH analysis.
  Sharmila Raghunandan, Juhi Jain, Debra Saxe, Melinda Pauly, Ahmed A Aljudi, Rhett P. Ketterling, Alexis B Carter, Sunil S. Raikar> ;Pediatric Blood & Cancer. 2021 Nov 12
• 48 citations
  PI3Kδ/γ inhibition promotes CART cell epigenetic and metabolic re-programming to enhance anti-tumor cytotoxicity
  Christopher Ronald Funk, Shuhua Wang, Kevin Z. Chen, Alexandra Waller, Aditi Sharma, Claudia L. Edgar, Vikas Gupta, Shanmuganathan Chandrakasan, Jaquelyn T. Zoine, And...> ;Blood. 2021 Sep 14
• Mixed phenotype acute leukemia in a child associated with a NUP98-NSD1 fusion and NRAS p.Gly61Arg mutation.
  Shireen S Ganapathi, Sunil S. Raikar, Svetlana A. Yatsenko, Miroslav Djokic, Andrew Bukowinski> ;Cancer Reports. 2021 Mar 30
• 12 citations
  Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds.
  Jamie A.G. Hamilton, Miyoung Lee, Rae Hunter, Raira S. Ank, Jamie Y. Story, Ganesh R. Talekar, Talia Sisroe, Dov B. Ballak, Andrew Fedanov, Christopher C. Porter, Elan...> ;Aging Cell. 2021 Jan 22
• 16 citations
  Bortezomib enhances cytotoxicity of ex vivo-expanded gamma delta T cells against acute myeloid leukemia and T-cell acute lymphoblastic leukemia.
  Jamie Y. Story, Jaquelyn T. Zoine, Rebecca E. Burnham, Jamie A.G. Hamilton, H. Trent Spencer, Christopher B. Doering, Sunil S. Raikar> ;Cytotherapy. 2021 Jan 1
• 2 citations
  Sustained Complete Molecular Remission With Imatinib Monotherapy in a Child Presenting With Blast Phase FIP1L1-PDGFRA-Associated Myeloid Neoplasm With Eosinophilia.
  Juhi Jain, Elizabeth P. Weinzierl, Debra Saxe, John Bergsagel, Jason Gotlib, Andreas Reiter, Sunil S. Raikar> ;Hemasphere. 2020 Nov 6
• 12 citations
  Significance of minimal residual disease in pediatric mixed phenotype acute leukemia: a multicenter cohort study.
  Matthew J. Oberley, Sunil S. Raikar, Gerald Wertheim, Jemily Malvar, Richard Sposto, Karen R. Rabin, Jyotinder N. Punia, Alix E. Seif, Viviane C. Cahen, Reuven J. Scho...> ;Leukemia. 2020 Feb 14
• 70 citations
  Targeting T cell malignancies using CAR-based immunotherapy: challenges and potential solutions.
  Lauren C. Fleischer, H. Trent Spencer, Sunil S. Raikar> ;Journal of Hematology & Oncology. 2019 Dec 29
• Clonal Evolution of B-Cell Acute Lymphoblastic Leukemia with del(9)(p13p21) into Mixed Phenotype Acute Leukemia Presenting as an Isolated Testicular Relapse.
  Miller, L., Saxe, D., Lew, G., Park, S., Raikar, S.> ;Reports. 2019 Sep 1
• 1 citations
  Acquired Hypofibrinogenemia Before Asparaginase Exposure During Induction Therapy for Pediatric Acute Lymphoblastic Leukemia: A Report of 2 Cases and Review of the Lit...
  Sunil S. Raikar, James Felker, Kavita N. Patel, Glen Lew, Robert F. Sidonio> ;Journal of Pediatric Hematology/oncology. 2018 Oct 1
• 56 citations
  Development of chimeric antigen receptors targeting T-cell malignancies using two structurally different anti-CD5 antigen binding domains in NK and CRISPR-edited T cel...
  Sunil S. Raikar, Lauren C. Fleischer, Robert Moot, Andrew Fedanov, Na Yoon Paik, Kristopher A. Knight, Christopher B. Doering, H. Trent Spencer> ;Oncoimmunology. 2018 Mar 4
• Hurdles Associated with the Translational Use of Genetically Modified Cells.
  Sunil S. Raikar, H. Trent Spencer> ;Current Stem Cell Reports. 2018 Feb 17
• 76 citations
  Improving T-cell expansion and function for adoptive T-cell therapy using ex vivo treatment with PI3Kδ inhibitors and VIP antagonists.
  Christopher T. Petersen, Mojibade Hassan, Anna B. Morris, Jasmin Jeffery, Kunhee Lee, Neera Jagirdar, Ashley D. Staton, Sunil S. Raikar, Harold Trent Spencer, Todd Sul...> ;Blood Advances. 2018 Feb 13
• 7 citations
  Hyperleukocytosis in infant acute leukemia: a role for manual exchange transfusion for leukoreduction.
  Daniel V. Runco, Cassandra D. Josephson, Sunil S. Raikar, Kelly C. Goldsmith, Glen Lew, Melinda Pauly, Ross M. Fasano> ;Transfusion. 2018 May 1
• 17 citations
  Isolated myeloperoxidase expression in pediatric B/myeloid mixed phenotype acute leukemia is linked with better survival.
  Sunil S. Raikar, Sunita I. Park, Traci Leong, David L. Jaye, Frank G. Keller, John T. Horan, William G. Woods> ;Blood. 2018 Feb 1
• 3 citations
  Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia
  Sunil S. Raikar, John Dallas Scarborough, Himalee S. Sabnis, John Bergsagel, David Wu, Todd M. Cooper, Frank G. Keller, Brent L. Wood, Silvia T. Bunting> ;Pediatric Blood & Cancer. 2016 Sep 1
• 22 citations
  Genetic engineering of chimeric antigen receptors using lamprey derived variable lymphocyte receptors
  Robert Moot, Sunil S. Raikar, Lauren C. Fleischer, Melissa Querrey, Daniel E Tylawsky, Hirotomo Nakahara, Christopher B. Doering, H. Trent Spencer> ;Molecular Therapy Oncolytics. 2016 Jan 1
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