SunilSudarshanMD

PubMed

• Are markers of survival associated with perioperative outcomes for tumor thrombectomy patients?
  Andrew M Fang, Stephen Leahy, Ava Saidian, Robert A Oster, Jeffrey W Nix, Sunil Sudarshan, Soroush Rais-Bahrami, Charles C Peyton> ;Urologic Oncology. 2023 Aug 1
• 2 citations
  Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma.
  Gia-Buu Tran, Jane Ding, Bingwei Ye, Mengling Liu, Yajie Yu, Yunhong Zha, Zheng Dong, Kebin Liu, Sunil Sudarshan, Han-Fei Ding> ;Cancer Research. 2023 Jul 5
• 7 citations
  Estrogen-related receptor gamma regulates mitochondrial and synaptic genes and modulates vulnerability to synucleinopathy.
  S N Fox, L J McMeekin, C H Savage, K L Joyce, S M Boas, M S Simmons, C B Farmer, J Ryan, L Pereboeva, K Becker, J Auwerx, S Sudarshan, J Ma, A Lee, R C Roberts, D K Cr...> ;NPJ Parkinson's Disease. 2022 Aug 18
• 1 citations
  Renal oncometabolite L-2-hydroxyglutarate imposes a block in kidney tubulogenesis: Evidence for an epigenetic basis for the L-2HG-induced impairment of differentiation.
  Mary Taub, Nader H Mahmoudzadeh, Jason M Tennessen, Sunil Sudarshan> ;Frontiers in Endocrinology. 2022 Jan 1
• 9 citations
  The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancer
  Hyeyoung Nam, Anirban Kundu, Suman Karki, Garrett J. Brinkley, Darshan S. Chandrashekar, Richard Kirkman, Juan Liu, Maria V. Liberti, Jason W. Locasale, Tanecia Mitche...> ;JCI Insight. 2021 Nov 22
• 6 citations
  The oncometabolite L-2-hydroxyglutarate is a common product of dipteran larval development.
  Nader H. Mahmoudzadeh, Alexander J. Fitt, Daniel B. Schwab, William E. Martenis, Lauren M. Nease, Charity G. Owings, Garrett J. Brinkley, Hongde Li, Jonathan A. Karty,...> ;Insect Biochemistry and Molecular Biology. 2020 Dec 1
• 6 citations
  Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney.
  Garrett Brinkley, Hyeyoung Nam, Eunhee Shim, Richard Kirkman, Anirban Kundu, Suman Karki, Yasaman Heidarian, Jason M Tennessen, Juan Liu, Jason W Locasale, Tao Guo, Sh...> ;Disease Models & Mechanisms. 2020 Nov 27
• 23 citations
  PRDM16 suppresses HIF-targeted gene expression in kidney cancer.
  Anirban Kundu, Hyeyoung Nam, Sandeep B. Shelar, Darshan S. Chandrashekar, Garrett J. Brinkley, Suman Karki, Tanecia Mitchell, Carolina B. Livi, Phillip Buckhaults, Ric...> ;The Journal of Experimental Medicine. 2020 Jun 1
• 1 citations
  Metastatic prostate cancer to an ischiorectal fossa lymph node identified on multiparametric magnetic resonance imaging.
  Andrew M. Fang, Samuel J. Galgano, Jennifer Gordetsky, Sunil Sudarshan, Andrew M. McDonald, Soroush Rais-Bahrami> ;Urology Annals. 2020 Apr 1
• 1 citations
  14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation.
  Anirban Kundu, Sandeep Shelar, Arindam P Ghosh, Mary Ballestas, Richard Kirkman, Hyeyoung Nam, Garrett J Brinkley, Suman Karki, James A Mobley, Sejong Bae, Sooryanaray...> ;The Journal of Biological Chemistry. 2020 Feb 7
• 15 citations
  PGC1α suppresses kidney cancer progression by inhibiting collagen-induced SNAIL expression.
  Hyeyoung Nam, Anirban Kundu, Garrett J. Brinkley, Darshan S. Chandrashekar, Richard Kirkman, Balabhadrapatruni V. S. K. Chakravarthi, Rachael M. Orlandella, Lyse A. No...> ;Matrix Biology. 2020 Jan 23
• 29 citations
  Integrative Epigenetic and Gene Expression Analysis of Renal Tumor Progression to Metastasis
  Hyeyoung Nam, Darshan S. Chandrashekar, Anirban Kundu, Sandeep B. Shelar, Eun-Young Kho, Guru Sonpavde, Gurudatta Naik, Pooja Ghatalia, Carolina B. Livi, Sooryanarayan...> ;Molecular Cancer Research. 2019 Jan 1
• 43 citations
  Biochemical and epigenetic insights into L-2-hydroxyglutarate, a potential therapeutic target in renal cancer
  Sandeep B. Shelar, Eun Hee Shim, Garrett J. Brinkley, Anirban Kundu, Francesca Carobbio, Tyler Poston, Jubilee Tan, Vishwas Parekh, Daniel Benson, David K. Crossman, P...> ;Clinical Cancer Research. 2018 Dec 15
• 19 citations
  Wnt receptor Frizzled 8 is a target of ERG in prostate cancer.
  Balabhadrapatruni V. S. K. Chakravarthi, Darshan S. Chandrashekar, Sai Akshaya Hodigere Balasubramanya, Alyncia D. Robinson, Shannon Carskadon, Uttam Rao, Jennifer Gor...> ;The Prostate. 2018 Dec 1
• 9 citations
  Kinomic profiling identifies focal adhesion kinase 1 as a therapeutic target in advanced clear cell renal cell carcinoma
  Arindam P. Ghosh, Christopher D. Willey, Joshua C. Anderson, Karim Welaya, Dongquan Chen, Amitkumar Mehta, Pooja Ghatalia, Ankit Madan, Gurudatta Naik, Sunil Sudarshan...> ;Oncotarget. 2017 Mar 18
• 19 citations
  Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic Targets.
  Pooja Ghatalia, Eddy S. Yang, Brittany N. Lasseigne, Ryne C. Ramaker, Sara J. Cooper, Dongquan Chen, Sunil Sudarshan, Shi Wei, Arjun S. Guru, Amy Zhao, Tiffiny Cooper,...> ;Plos One. 2016 Aug 30
• 6 citations
  Genetics of renal cancer: focus on MTOR
  Arindam P. Ghosh, Sunil Sudarshan> ;Aging. 2016 Mar 26
• 30 citations
  High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes
  Joshua C. Anderson, Christopher D. Willey, Amitkumar Mehta, Karim Welaya, Dongquan Chen, Christine W. Duarte, Pooja Ghatalia, Waleed Arafat, Ankit Madan, Sunil Sudarsh...> ;Plos One. 2015 Sep 25
• 53 citations
  Point mutations of the mTOR-RHEB pathway in renal cell carcinoma.
  Arindam P. Ghosh, Christopher B. Marshall, Tatjana Coric, Eun-Hee Shim, Richard Kirkman, Mary E. Ballestas, Mitsuhiko Ikura, Mary-Ann Bjornsti, Sunil Sudarshan> ;Oncotarget. 2015 Jul 22
• 14 citations
  Another small molecule in the oncometabolite mix: L-2-Hydroxyglutarate in kidney cancer.
  Eun-Hee Shim, Sunil Sudarshan> ;Oncoscience. 2015 May 15
• 187 citations
  L-2-Hydroxyglutarate: An Epigenetic Modifier and Putative Oncometabolite in Renal Cancer
  Eun Hee Shim, Carolina B. Livi, Dinesh Rakheja, Jubilee Tan, Daniel Benson, Vishwas Parekh, Eun Young Kho, Arindam P. Ghosh, Richard Kirkman, Sadanan Velu, Shilpa Dutt...> ;Cancer Discovery. 2014 Nov 1
• 40 citations
  The oncometabolite fumarate promotes pseudohypoxia through noncanonical activation of NF-κB signaling.
  Karthigayan Shanmugasundaram, Bijaya K. Nayak, Eun Hee Shim, Carolina B. Livi, Karen Block, Sunil Sudarshan> ;The Journal of Biological Chemistry. 2014 Aug 29
• 3 citations
  Do the sites of metastases provide additional information regarding prognosis and biology in renal cell carcinoma
  Guru Sonpavde, Sunil Sudarshan, Bernard Escudier> ;European Urology. 2014 Mar 1
• 21 citations
  Fibroblast growth factor receptors as therapeutic targets in clear-cell renal cell carcinoma
  Guru Sonpavde, Christopher D. Willey, Sunil Sudarshan> ;Expert Opinion on Investigational Drugs. 2014 Feb 12
• 43 citations
  Stabilization of HIF-2α through redox regulation of mTORC2 activation and initiation of mRNA translation
  Bijaya K. Nayak, Denis Feliers, Sunil Sudarshan, William E. Friedrichs, Robert T. Day, David D. New, John Fitzgerald, Assaad A. Eid, Thomas DeNapoli, Dipen J. Parekh, ...> ;Oncogene. 2013 Jun 27
• Join now to see all