SunwenChouMD

PubMed

• Ganciclovir and maribavir cross-resistance revisited: Relative drug susceptibilities of canonical cytomegalovirus mutants.
  Chou, S., Watanabe, J.> ;Antiviral Research. 2024 Feb 1
• 2 citations
  Use of next-generation sequencing to detect mutations associated with antiviral drug resistance in cytomegalovirus.
  Nicholas T Streck, Mark J Espy, Matthew J Ferber, Eric W Klee, Raymund R Razonable, Dimitri Gonzalez, Chalom Sayada, Phillip R Heaton, Sunwen Chou, Matthew J Binnicker> ;Journal of Clinical Microbiology. 2023 Oct 24
• 10 citations
  Drug Resistance Assessed in a Phase 3 Clinical Trial of Maribavir Therapy for Refractory or Resistant Cytomegalovirus Infection in Transplant Recipients.
  Sunwen Chou, Sophie Alain, Carlos Cervera, Roy F Chemaly, Camille N Kotton, Jens Lundgren, Genovefa A Papanicolaou, Marcus R Pereira, Jingyang J Wu, Rose Ann Murray, N...> ;The Journal of Infectious Diseases. 2024 Feb 14
• 8 citations
  Relative frequency of cytomegalovirus UL56 gene mutations detected in genotypic letermovir resistance testing.
  Sunwen Chou, Steven Kleiboeker> ;Antiviral Research. 2022 Nov 1
• 5 citations
  Highly Conserved Interaction Profiles between Clinically Relevant Mutants of the Cytomegalovirus CDK-like Kinase pUL97 and Human Cyclins: Functional Significance of Cy...
  Martin Schütz, Regina Müller, Eileen Socher, Christina Wangen, Florian Full, Emanuel Wyler, Diana Wong, Myriam Scherer, Thomas Stamminger, Sunwen Chou, William D Rawli...> ;International Journal of Molecular Sciences. 2022 Oct 5
• 1 citations
  Opposite effects of cytomegalovirus UL54 exonuclease domain mutations on acyclovir and cidofovir susceptibility.
  Sunwen Chou> ;Antiviral Research. 2021 Nov 1
• 11 citations
  Ganciclovir and maribavir susceptibility phenotypes of cytomegalovirus UL97 ATP binding region mutations detected by expanded genotypic testing
  Sunwen Chou, Matthew Watters, Rohita Sinha, Steven Kleiboeker> ;Antiviral Research. 2021 Sep 1
• 39 citations
  Drug resistance mutations and associated phenotypes detected in clinical trials of maribavir for treatment of cytomegalovirus infection.
  Sunwen Chou, Kening Song, Jingyang Wu, Tien Bo, Clyde S. Crumpacker> ;The Journal of Infectious Diseases. 2020 Jul 29
• 54 citations
  Advances in the genotypic diagnosis of cytomegalovirus antiviral drug resistance.
  Sunwen Chou> ;Antiviral Research. 2020 Jan 12
• 43 citations
  Letermovir Resistance Analysis in a Clinical Trial of Cytomegalovirus Prophylaxis for Hematopoietic Stem Cell Transplant Recipients.
  Cameron M. Douglas, Richard J. O. Barnard, Daniel J. Holder, Randi Y. Leavitt, Diane Levitan, Maureen Maguire, David C. Nickle, Valerie L Teal, Hong Wan, Dirk C.J.G. v...> ;The Journal of Infectious Diseases. 2020 Mar 16
• 17 citations
  Novel UL97 drug resistance mutations identified at baseline in a clinical trial of maribavir for resistant or refractory cytomegalovirus infection.
  Sunwen Chou, Jingyang Wu, Kening Song, Tien Bo> ;Antiviral Research. 2019 Dec 1
• 115 citations
  Definitions of Resistant and Refractory Cytomegalovirus Infection and Disease in Transplant Recipients for Use in Clinical Trials.
  Roy F. Chemaly, Sunwen Chou, Hermann Einsele, Paul D. Griffiths, Robin K. Avery, Raymund R. Razonable, Kathleen M. Mullane, Camille N. Kotton, Jens D Lundgren, Takashi...> ;Clinical Infectious Diseases. 2019 Apr 8
• 92 citations
  Emergence of letermovir resistance in a lung transplant recipient with ganciclovir-resistant cytomegalovirus infection.
  Lauren Cherrier, Aasya Nasar, Kellie J Goodlet, Michael D Nailor, Sofya Tokman, Sunwen Chou> ;American Journal of Transplantation. 2018 Oct 29
• 37 citations
  Antiviral activity of maribavir in combination with other drugs active against human cytomegalovirus.
  Sunwen Chou, Ronald J. Ercolani, Katayoun Derakhchan> ;Antiviral Research. 2018 Sep 1
• 41 citations
  New Locus of Drug Resistance in the Human Cytomegalovirus UL56 Gene Revealed by In Vitro Exposure to Letermovir and Ganciclovir.
  Sunwen Chou, L. Elizabeth Satterwhite, Ronald J. Ercolani> ;Antimicrobial Agents and Chemotherapy. 2018 Aug 27
• 250 citations
  The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation.
  Camille N Kotton, Deepali Kumar, Angela M Caliendo, Shirish Huprikar, Sunwen Chou, Lara Danziger-Isakov, Atul Humar> ;Transplantation. 2018 Jun 1
• 56 citations
  Use of Viral Load as a Surrogate Marker in Clinical Studies of Cytomegalovirus in Solid Organ Transplantation: A Systematic Review and Meta-analysis.
  Yoichiro Natori, Ali Alghamdi, Mahmood Tazari, Veronica Miller, Shahid Husain, Takashi E. Komatsu, Paul D. Griffiths, Per Ljungman, Ani Orchanian-Cheff, Deepali Kumar,...> ;Clinical Infectious Diseases. 2018 Feb 1
• 59 citations
  A third component of the human cytomegalovirus terminase complex is involved in letermovir resistance
  Sunwen Chou> ;Antiviral Research. 2017 Oct 28
• 32 citations
  Comparison of Cytomegalovirus Terminase Gene Mutations Selected after Exposure to Three Distinct Inhibitor Compounds
  Sunwen Chou> ;Antimicrobial Agents and Chemotherapy. 2017 Nov 1
• 13 citations
  Identification of a Short Sequence in the HCMV Terminase pUL56 Essential for Interaction With pUL89 Subunit
  Gaëtan Ligat, C Jacquet, Sunwen Chou, A Couvreux, Sophie Alain, Sébastien Hantz> ;Scientific Reports. 2017 Aug 18
• 18 citations
  Differentiated Levels of Ganciclovir Resistance Conferred by Mutations at Codons 591 to 603 of the Cytomegalovirus UL97 Kinase Gene.
  Sunwen Chou, Ronald J. Ercolani, Adam L. Vanarsdall> ;Journal of Clinical Microbiology. 2017 Apr 26
• 14 citations
  Foscarnet resistance mutations mapping to atypical domains of the cytomegalovirus DNA polymerase gene.
  Sunwen Chou> ;Antiviral Research. 2017 Feb 1
• 34 citations
  The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors.
  Corina Hutterer, Stuart T. Hamilton, Mirjam Steingruber, Isabel Zeitträger, Hanife Bahsi, N. Thuma, Zin Naing, Z. Örfi, Laszlo Orfi, E. Socher, Heinrich Sticht, Willia...> ;Antiviral Research. 2016 Oct 1
• 13 citations
  Analysis of Mutations in the Gene Encoding Cytomegalovirus DNA Polymerase in a Phase 2 Clinical Trial of Brincidofovir Prophylaxis
  E. Randall Lanier, Scott Foster, Tom Brundage, Sunwen Chou, Mark N. Prichard, Steven Kleiboeker, Chad Wilson, Donella Colville, Herve Mommeja-Marin> ;The Journal of Infectious Diseases. 2016 Jul 1
• 24 citations
  Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance
  Sunwen Chou, Ronald J. Ercolani, E. Randall Lanier> ;Antimicrobial Agents and Chemotherapy. 2016 Jun 1
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