SusanCarolGubaMD

PubMed

• 10 citations
  Phase Ib/II Study of Enzalutamide with Samotolisib (LY3023414) or Placebo in Patients with Metastatic Castration-Resistant Prostate Cancer.
  Christopher J Sweeney, Ivor J Percent, Sunil Babu, Jennifer L Cultrera, Bryan A Mehlhaff, Oscar B Goodman, David S Morris, Ian D Schnadig, Costantine Albany, Neal D Sh...> ;Clinical Cancer Research. 2022 Jun 1
• 87 citations
  Safety and activity of the TGFβ receptor I kinase inhibitor galunisertib plus the anti-PD-L1 antibody durvalumab in metastatic pancreatic cancer
  Davide Melisi, Do Youn Oh, Antoine Hollebecque, Emiliano Calvo, Anna M. Varghese, Erkut Borazanci, Teresa Macarulla, Valeria Merz, Camilla Zecchetto, Yumin Zhao, Iveli...> ;Journal for Immunotherapy of Cancer. 2021 Mar 1
• 61 citations
  Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemo...
  Antje Wick, Annick Desjardins, Cristina Suarez, Peter A. Forsyth, Ivelina Gueorguieva, Tiana L. Burkholder, Ann Cleverly, Shawn T. Estrem, Shuaicheng Wang, Michael Lah...> ;Investigational New Drugs. 2020 Mar 5
• 45 citations
  Phase II Study of the ALK5 Inhibitor Galunisertib in Very Low-, Low-, and Intermediate-Risk Myelodysplastic Syndromes.
  Valeria Santini, David Valcárcel, Uwe Platzbecker, Rami S. Komrokji, Ann Cleverly, Michael Lahn, Jan Janssen, Yumin Zhao, Alan Chiang, Aristoteles Giagounidis, Susan C...> ;Clinical Cancer Research. 2019 Dec 1
• 21 citations
  Biomarker and Histopathology Evaluation of Patients with Recurrent Glioblastoma Treated with Galunisertib, Lomustine, or the Combination of Galunisertib and Lomustine.
  David Capper, Andreas von Deimling, Alba A. Brandes, Antoine F. Carpentier, Santosh Kesari, Juan M. Sepúlveda-Sánchez, Helen Wheeler, Olivier Chinot, Lawrence Cher, Jo...> ;International Journal of Molecular Sciences. 2017 May 6
• 169 citations
  A Phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma
  Alba A. Brandes, Antoine F. Carpentier, Santosh Kesari, Juan M. Sepúlveda-Sánchez, Helen Wheeler, Olivier Chinot, Lawrence Cher, Joachim P. Steinbach, David Capper, Po...> ;Neuro-Oncology. 2016 Aug 1
• 29 citations
  Relationship between efficacy outcomes and weight gain during treatment of advanced, non-squamous, non-small-cell lung cancer patients
  Jyoti D. Patel, José Rodrigues Pereira, Jian Chen, Jingyi Liu, Susan C. Guba, William J. John, Mauro Orlando, G.V. Scagliotti, Philip Bonomi> ;Annals of Oncology. 2016 Aug 1
• 381 citations
  Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway
  Stephan Herbertz, J. Scott Sawyer, Anja Stauber, Ivelina Gueorguieva, Kyla Driscoll, Shawn T. Estrem, Ann Cleverly, Durisala Desaiah, Susan C. Guba, Karim A. Benhadji,...> ;Drug Design, Development and Therapy. 2015 Aug 10
• 4 citations
  Exploratory Subset Analysis of African Americans From the PointBreak Study: Pemetrexed-Carboplatin-Bevacizumab Followed by Maintenance Pemetrexed-Bevacizumab Versus Pa...
  Craig H. Reynolds, Jyoti D. Patel, Edward B. Garon, Mark R. Olsen, Philip Bonomi, Ramaswamy Govindan, Eduardo J. Pennella, Jingyi Liu, Susan C. Guba, Shi Li, David R. ...> ;Clinical Lung Cancer. 2015 May 1
• 18 citations
  Quality of Life Analyses from the Randomized, Open-Label, Phase III PointBreak Study of Pemetrexed-Carboplatin-Bevacizumab followed by Maintenance Pemetrexed-Bevacizum...
  David R. Spigel, Jyoti D. Patel, Craig H. Reynolds, Edward B. Garon, Robert C. Hermann, Ramaswamy Govindan, Mark R. Olsen, Katherine B. Winfree, Jian Chen, Jingyi Liu,...> ;Journal of Thoracic Oncology. 2015 Feb 1
• 114 citations
  PRONOUNCE: randomized, open-label, phase III study of first-line pemetrexed + carboplatin followed by maintenance pemetrexed versus paclitaxel + carboplatin + bevacizu...
  Ralph Zinner, Coleman K. Obasaju, David R. Spigel, Robert W. Weaver, J. Thaddeus Beck, David M. Waterhouse, Manuel R. Modiano, Borys Hrinczenko, Petros G. Nikolinakos,...> ;Journal of Thoracic Oncology. 2015 Jan 1
• 273 citations
  PointBreak: A Randomized Phase III Study of Pemetrexed Plus Carboplatin and Bevacizumab Followed by Maintenance Pemetrexed and Bevacizumab Versus Paclitaxel Plus Carbo...
  Jyoti D. Patel, Mark A. Socinski, Edward B. Garon, Craig H. Reynolds, David R. Spigel, Mark R. Olsen, Robert C. Hermann, Robert M. Jotte, Thaddeus Beck, Donald A. Rich...> ;Journal of Clinical Oncology. 2013 Dec 1
• 22 citations
  Baseline quality of life and performance status as prognostic factors in patients with extensive-stage disease small cell lung cancer treated with pemetrexed plus carb...
  Martin Reck, Nick Thatcher, Egbert F. Smit, Paul Lorigan, Ewa Szutowicz-Zielińska, Astra M. Liepa, Katherine B. Winfree, Patrick Peterson, Susan C. Guba, Mark A. Socinski> ;Lung Cancer. 2012 Dec 1
• Biomarker analysis in a phase III study of pemetrexed-carboplatin versus etoposide-carboplatin in chemonaive patients with extensive-stage small-cell lung cancer.
  Smit EF, Socinski MA, Mullaney BP, Myrand SP, Scagliotti GV, Lorigan P, Reck M, Ciuleanu T, von Pawel J, Karaseva NA, Szczesna A, Ohannesian D, Powell E, Hozak RR, Hon...> ;Ann. Oncol.. 2012-07-01
• 28 citations
  Pemetrexed therapy in elderly patients with good performance status: analysis of two phase III trials of patients with nonsquamous non-small-cell lung cancer.
  Cesare Gridelli, Thomas Brodowicz, Corey J. Langer, Patrick Peterson, Mominul Islam, Susan C. Guba, Patti Moore, Carla Visseren-Grul, Giorgio V. Scagliotti> ;Clinical Lung Cancer. 2012 Sep 1
• 136 citations
  Phase III Study of Pemetrexed Plus Carboplatin Compared With Etoposide Plus Carboplatin in Chemotherapy-Naive Patients With Extensive-Stage Small-Cell Lung Cancer
  Mark A. Socinski, Egbert F. Smit, Paul Lorigan, Kartik Konduri, Martin Reck, Aleksandra Szczesna, Johnetta Blakely, Piotr Serwatowski, Nina Karaseva, Tudor Ciuleanu, J...> ;Journal of Clinical Oncology. 2009 Oct 1
• 54 citations
  Treatment Rationale and Study Design for the PointBreak Study: A Randomized, Open-label Phase III Study of Pemetrexed/Carboplatin/Bevacizumab Followed by Maintenance P...
  Jyoti D. Patel, Philip Bonomi, Mark A. Socinski, Ramaswamy Govindan, Shengyan Hong, Coleman K. Obasaju, Eduardo J. Pennella, Allicia C. Girvan, Susan C. Guba> ;Clinical Lung Cancer. 2009 Jul 1
• Pharmacogenomic analysis from a phase III study of pemetrexed plus carboplatin (PC) versus etoposide plus carboplatin (EC) in chemonaive patients (pts) with extensive-...
  Smit EF, Socinski MA, Mullaney BP, Myrand SP, Powell E, Lorigan P, Kaiser C, Guba SC, Thatcher N> ;J. Clin. Oncol.. 2009-05-20
• 73 citations
  The gemcitabine, docetaxel, and capecitabine (GTX) regimen for metastatic pancreatic cancer: a retrospective analysis
  Robert L. Fine, David R. Fogelman, Stephen M. Schreibman, Manisha Desai, William H. Sherman, James Strauss, Susan Guba, Riolan Andrade, John A. Chabot> ;Cancer Chemotherapy and Pharmacology. 2007 Apr 18
• GTX chemotherapy for metastatic pancreatic cancer: Response, survival, and toxicity data.
  Fine RL, Fogelman DR, Schreibman S, Guba S, Sharma J, Shapiro G> ;J. Clin. Oncol.. 2004-07-15
• 91 citations
  Hyperhomocysteinemia and the Endocrine System: Implications for Atherosclerosis and Thrombosis
  Vivian Fonseca, Susan C. Guba, Louis M. Fink> ;Endocrine Reviews. 1999 Oct 1
• 49 citations
  Hyperhomocysteinemia and thrombosis.
  Susan C. Guba, Vivian Fonseca, Louis M. Fink> ;Seminars in Thrombosis and Hemostasis. 1999 Jan 1
• 69 citations
  Hyperhomocysteinemia:An Emerging and Important Risk Factor for Thromboembolic and Cardiovascular Disease
  Susan C. Guba, Louis M. Fink, Vivian Fonseca> ;American Journal of Clinical Pathology. 1996 Dec 1
• 72 citations
  Interferon-alpha restores the deficient expression of the cytoadhesion molecule lymphocyte function antigen-3 by chronic myelogenous leukemia progenitor cells.
  G. Upadhyaya, S. C. Guba, S. A. Sih, Andrew P. Feinberg, M. Talpaz, Hagop M. Kantarjian, Albert B. Deisseroth, Stephen G. Emerson> ;The Journal of Clinical Investigation. 1991 Dec 1
• 42 citations
  Regulation of interleukin 3 gene induction in normal human T cells.
  Susan C. Guba, Gregory Stella, Laurence A. Turka, Carl H. June, Craig B. Thompson, Stephen G. Emerson> ;The Journal of Clinical Investigation. 1989 Dec 1
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