SusanRedlineMD

Pulmonology • Boston, MA

Critical Care Medicine, Pleural Disease, Sleep Medicine

Professor of Sleep Medicine

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Office
221 longwood ave
Brigham and Women's hospital
Boston, MA 02215
Phone+1 617-732-5859
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Education & Training

Brigham and Women's HospitalResidency, Internal Medicine, 1984 - 1987
The MetroHealth System/Case Western Reserve UniversityFellowship, Pulmonary Disease and Critical Care Medicine, 1980 - 1984
The MetroHealth System/Case Western Reserve UniversityInternship, Internal Medicine, 1979 - 1980
Boston University School of MedicineClass of 1979

Certifications & Licensure

OH State Medical License 1981 - 2026
MA State Medical License 1984 - 2025
RI State Medical License 1987 - 1991
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Clinical Trials

Sleep Heart Health Study (SHHS) Data Coordinating Center Start of enrollment: 1994 Sep 01
Completed
Familial Aggregation and Natural History of Sleep Apnea Start of enrollment: 1990 Aug 01
Completed
Outcomes of Sleep Disorders in Older Men Start of enrollment: 2003 Sep 01
Completed
Childhood Adenotonsillectomy Study for Children With OSAS Start of enrollment: 2007 Oct 01
Completed
Not Applicable
Heart Biomarker Evaluation in Apnea Treatment Start of enrollment: 2010 Feb 01
Completed
Phase 2
Sleep Apnea Intervention for Cardiovascular Disease Reduction Start of enrollment: 2011 Mar 01
Completed
Not Applicable
Effects of Treatment of Sleep Apnea on Metabolic Syndrome Start of enrollment: 2004 Jan 01
Completed
Phase 2
Personalized Asthma Care Team Start of enrollment: 2005 Jul 01
Completed
Pediatric Adenotonsillectomy Trial for Snoring Start of enrollment: 2016 Jun 01
Completed
Not Applicable
Adapting Sleep and Yoga Interventions for Maximal Effectiveness in Low Income Populations Start of enrollment: 2018 Jan 10
Completed
Not Applicable
Healthy Sleep for Children With Down Syndrome Start of enrollment: 2019 May 22
Completed
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Publications & Presentations

PubMed

Disparities in Sleep-Disordered Breathing: Upstream Risk Factors, Mechanisms, and Implications.
Seyni Gueye-Ndiaye, Ariel A Williamson, Susan Redline> ;Clinics in Chest Medicine. 2023 Sep 1
39 citations
International Consensus Statement on Obstructive Sleep Apnea.
Creamer, J. L., Jolie L Chang, Andrew N Goldberg, Jeremiah A Alt, Alzoubaidi Mohammed, Liza Ashbrook, Dennis Auckley, Indu Ayappa, Hira Bakhtiar, José E Barrera, Betha...> ;International Forum of Allergy & Rhinology. 2023 Jul 1
4 citations
Cardiovascular Outcomes in Adults with Coronary Artery Disease and Obstructive Sleep Apnea with versus without Excessive Daytime Sleepiness in the RICCADSA Cinical Trial.
Christine Eulenburg, Yeliz Celik, Susan Redline, Erik Thunström, Helena Glantz, Patrick J Strollo Jr, Yüksel Peker> ;Annals of the American Thoracic Society. 2023 Jul 1
1 citations
Obstructive Sleep Apnea and Longitudinal Changes in Interstitial Lung Imaging and Lung Function: The MESA Study.
John S Kim, Ali Azarbarzin, Anna J Podolanczuk, Michaela R Anderson, Brian E Cade, Steven M Kawut, Artur Wysoczanski, Andrew F Laine, Eric A Hoffman, Daniel J Gottlieb...> ;Annals of the American Thoracic Society. 2023 May 1
12 citations
Sleep Irregularity and Subclinical Markers of Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis.
Kelsie M Full, Tianyi Huang, Neomi A Shah, Matthew A Allison, Erin D Michos, Daniel A Duprez, Susan Redline, Pamela L Lutsey> ;Journal of the American Heart Association. 2023 Feb 21
1 citations
Automated Sleep Stages Classification Using Convolutional Neural Network From Raw and Time-Frequency Electroencephalogram Signals: Systematic Evaluation Study.
Shahab Haghayegh, Kun Hu, Katie Stone, Susan Redline, Eva Schernhammer> ;Journal of Medical Internet Research. 2023 Feb 10
1 citations
An integrated multi-omics analysis of sleep-disordered breathing traits implicates P2XR4 purinergic signaling.
Nuzulul Kurniansyah, Danielle A Wallace, Ying Zhang, Bing Yu, Brian Cade, Heming Wang, Heather M Ochs-Balcom, Alexander P Reiner, Alberto R Ramos, Joshua D Smith, Jian...> ;Communications Biology. 2023 Jan 31
2 citations
Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants.
Kristin L Young, Virginia Fisher, Xuan Deng, Jennifer A Brody, Misa Graff, Elise Lim, Bridget M Lin, Hanfei Xu, Najaf Amin, Ping An, Stella Aslibekyan, Alison E Fohner...> ;HGG Advances. 2023 Jan 12
Risk of Sleep Apnea Is Associated with Abdominal Obesity Among Asian Americans: Comparing Waist-to-Hip Ratio and Body Mass Index.
Sunmin Lee, Soomin Ryu, Grace E Lee, Susan Redline, Brittany N Morey> ;Journal of Racial and Ethnic Health Disparities. 2024 Feb 1
2 citations
Association between insomnia phenotypes and subclinical myocardial injury: the Multi-Ethnic Study of Atherosclerosis.
Fjola D Sigurdardottir, Suzanne M Bertisch, Michelle L Reid, Christopher R deFilippi, Joao A C Lima, Susan Redline, Torbjørn Omland> ;Sleep. 2023 Apr 12
5 citations
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits.
Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E Cade, Heming Wang, Tamar Sofer, Daniel S Evans, Katie L Stone, Sina A Gharib, Sutapa Mukherjee, Lyle J Palme...> ;Plos Genetics. 2022 Dec 1
21 citations
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Stavroula Kanoni, Sarah E Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Xiang Zhu, Shoa L Clarke, Konain Fatima Bhatti, Sailaja Vedantam, Thomas W Winkler, Adam E L...> ;Genome Biology. 2022 Dec 27
9 citations
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies.
Xihao Li, Corbin Quick, Hufeng Zhou, Sheila M Gaynor, Yaowu Liu, Han Chen, Margaret Sunitha Selvaraj, Ryan Sun, Rounak Dey, Donna K Arnett, Lawrence F Bielak, Joshua C...> ;Nature Genetics. 2023 Jan 1
3 citations
Association between psychotropic medication and sleep microstructure: evidence from large population studies.
Simon Hartmann, Liborio Parrino, Kristine Ensrud, Katie L Stone, Susan Redline, Scott R Clark, Mathias Baumert> ;Journal of Clinical Sleep Medicine. 2023 Mar 1
4 citations
Development and validation of a metabolite index for obstructive sleep apnea across race/ethnicities.
Ying Zhang, Debby Ngo, Bing Yu, Neomi A Shah, Han Chen, Alberto R Ramos, Phyllis C Zee, Russell Tracy, Peter Durda, Robert Kaplan, Martha L Daviglus, Stephen S Rich, J...> ;Scientific Reports. 2022 Dec 16
3 citations
Associations between evening shift work, irregular sleep timing, and gestational diabetes in the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b).
Danielle A Wallace, Kathryn Reid, William A Grobman, Francesca L Facco, Robert M Silver, Grace W Pien, Judette Louis, Phyllis C Zee, Susan Redline, Tamar Sofer> ;Sleep. 2023 Apr 12
7 citations
Genetic associations between sleep traits and cognitive ageing outcomes in the Hispanic Community Health Study/Study of Latinos.
Yuan Zhang, Michael Elgart, Einat Granot-Hershkovitz, Heming Wang, Wassim Tarraf, Alberto R Ramos, Ariana M Stickel, Donglin Zeng, Tanya P Garcia, Fernando D Testai, S...> ;Ebiomedicine. 2023 Jan 1
4 citations
Correlations between complex human phenotypes vary by genetic background, gender, and environment.
Michael Elgart, Matthew O Goodman, Carmen Isasi, Han Chen, Alanna C Morrison, Paul S de Vries, Huichun Xu, Ani W Manichaikul, Xiuqing Guo, Nora Franceschini, Bruce M P...> ;Cell Reports. Medicine. 2022 Dec 20
83 citations
Genetic diversity fuels gene discovery for tobacco and alcohol use.
Gretchen R B Saunders, Xingyan Wang, Fang Chen, Seon-Kyeong Jang, Mengzhen Liu, Chen Wang, Shuang Gao, Yu Jiang, Chachrit Khunsriraksakul, Jacqueline M Otto, Clifton A...> ;Nature. 2022 Dec 1
4 citations
Correlates of daytime sleepiness and insomnia among adults in Samoa.
Lacey W Heinsberg, Jenna C Carlson, Alysa Pomer, Brian E Cade, Take Naseri, Muagututia Sefuiva Reupena, Daniel E Weeks, Stephen T McGarvey, Susan Redline, Nicola L Hawley> ;Sleep Epidemiology. 2022 Dec 1
10 citations
Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension - 2021 NHLBI Workshop Report.
Michelle L Gumz, Daichi Shimbo, Marwah Abdalla, Ravi C Balijepalli, Christian Benedict, Yabing Chen, David J Earnest, Karen L Gamble, Scott R Garrison, Ming C Gong, Jo...> ;Hypertension. 2023 Mar 1
24 citations
Redefining Cardiovascular Health to Include Sleep: Prospective Associations With Cardiovascular Disease in the MESA Sleep Study.
Nour Makarem, Cecilia Castro-Diehl, Marie-Pierre St-Onge, Susan Redline, Steven Shea, Donald Lloyd-Jones, Hongyan Ning, Brooke Aggarwal> ;Journal of the American Heart Association. 2022 Nov 1
Sleep apnea and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA): leveraging state-of-the-art vascular imaging.
Neomi Shah, Michelle Reid, Venkatesh Mani, Vaishnavi Kundel, Robert C Kaplan, Jorge R Kizer, Zahi A Fayad, Steven Shea, Susan Redline> ;The International Journal of Cardiovascular Imaging. 2023 Mar 1
30 citations
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Zilin Li, Xihao Li, Hufeng Zhou, Sheila M Gaynor, Margaret Sunitha Selvaraj, Theodore Arapoglou, Corbin Quick, Yaowu Liu, Han Chen, Ryan Sun, Rounak Dey, Donna K Arnet...> ;Nature Methods. 2022 Dec 1
8 citations
Pathophysiology Underlying Demographic and Obesity Determinants of Sleep Apnea Severity.
Scott A Sands, Raichel M Alex, Dwayne Mann, Daniel Vena, Philip I Terrill, Laura K Gell, Andrey Zinchuk, Tamar Sofer, Sanjay R Patel, Luigi Taranto-Montemurro, Ali Aza...> ;Annals of the American Thoracic Society. 2023 Mar 1
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Journal Articles

The Hypoxic Burden of Sleep Apnoea Predicts Cardiovascular Disease-Related Mortality: The Osteoporotic Fractures in Men Study and the Sleep Heart Health Study
Kristine Ensrud, David P White, Susan Redline, European Heart Journal
Habitual Sleep Quality, Plasma Metabolites and Risk of Coronary Heart Disease in Post-Menopausal Women
Susan Redline, Elizabeth M Poole, JoAnn E Manson, Kathryn M Rexrode, International Journal of Epidemiology
What’s Sleep Got to Do with It?: Sleep Health and Sexual Risk-Taking Among Men Who Have Sex with Men
Susan Redline, MD, AIDS and Behavior
Rest‐Activity Rhythms and Cognitive Decline in Older Men: The Osteoporotic Fractures in Men Sleep Study
Nancy E Lane, Kristine Yaffe, Susan Redline, Kristine E Ensrud, Erin LeBlanc, Journal of the American Geriatrics Society
The National Sleep Research Resource: Towards a Sleep Data Commons
Matthew Kim, Susan Redline, Journal of the American Medical Informatics Association
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Press Mentions

How Cardiologists Perceive Obstructive Sleep Apnea in Atrial Fibrillation PatientsMarch 26th, 2023
Why Tech May Be Key to Improving Patient ComplianceMarch 2nd, 2022
Why Snoring During Pregnancy Could Be a Worrying SignFebruary 12th, 2022
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Hospital Affiliations

Brigham and Women's HospitalBoston, Massachusetts