SyedMAlamMD

PubMed

• Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
  Krebs, S. J.,Kwon, Y. D.,Schramm, C. A.,Law, W. H.,Donofrio, G.,Zhou, K. H.,Gift, S.,Dussupt, V.,Georgiev, I. S.,Schätzle, S.,McDaniel, J. R.,Lai, Y. T.,Sastry, M.,Zha...> ;Immunity. 2019 Mar 17
• Selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in HIV-1 broadly neutralizing antibodies.
  Henderson, R.,Watts, B. E.,Ergin, H. N.,Anasti, K.,Parks, R.,Xia, S. M.,Trama, A.,Liao, H. X.,Saunders, K. O.,Bonsignori, M.,Wiehe, K.,Haynes, B. F.,Alam, S. M.> ;Nat Commun. 2019 Feb 10
• Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier.
  Bonsignori, M.,Scott, E.,Wiehe, K.,Easterhoff, D.,Alam, S. M.,Hwang, K. K.,Cooper, M.,Xia, S. M.,Zhang, R.,Montefiori, D. C.,Henderson, R.,Nie, X.,Kelsoe, G.,Moody, M....> ;Immunity. 2018 Dec 16
• Adjuvant-dependent enhancement of HIV Env-specific antibody responses in infant rhesus macaques.
  Phillips, B.,Van Rompay, KKA.,Rodriguez-Nieves, J.,Lorin, C.,Koutsoukos, M.,Tomai, M.,Fox, C. B.,Eudailey, J.,Dennis, M.,Alam, S. M.,Hudgens, M.,Fouda, G.,Pollara, J.,...> ;J. Virol.. 2018 Aug 10
• HASH(0x2472820)
  Dennison, S. M.,Reichartz, M.,Seaton, K. E.,Dutta, S.,Wille-Reece, U.,Hill, AVS.,Ewer, K. J.,Rountree, W.,Sarzotti-Kelsoe, M.,Ozaki, D. A.,Alam, S. M.,Tomaras, G. D.> ;J. Immunol.. 2018 Jul 15
• HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.
  Yates, N. L.,deCamp, A. C.,Korber, B. T.,Liao, H. X.,Irene, C.,Pinter, A.,Peacock, J.,Harris, L. J.,Sawant, S.,Hraber, P.,Shen, X.,Rerks-Ngarm, S.,Pitisuttithum, P.,Ni...> ;J. Virol.. 2018 Feb 02
• HIV-1 Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galcer Blocking and Phagocytosis
  Barton F Haynes, S Munir Alam, Robert Parks, Nelson L Michael, Merlin L Robb, M Anthony Moody, Jerome H Kim> ;mBio. 2018 Jan 13
• Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models.
  Saunders, K. O.,Verkoczy, L. K.,Jiang, C.,Zhang, J.,Parks, R.,Chen, H.,Housman, M.,Bouton-Verville, H.,Shen, X.,Trama, A. M.,Scearce, R.,Sutherland, L.,Santra, S.,Newm...> ;Cell Rep. 2017 Dec 28
• HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine.
  Shen, X.,Basu, R.,Sawant, S.,Beaumont, D.,Kwa, S. F.,LaBranche, C.,Seaton, K. E.,Yates, N. L.,Montefiori, D. C.,Ferrari, G.,Wyatt, L. S.,Moss, B.,Alam, S. M.,Haynes, B...> ;J. Virol.. 2017 Oct 13
• Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
  Williams, W. B.,Zhang, J.,Jiang, C.,Nicely, N. I.,Fera, D.,Luo, K.,Moody, M. A.,Liao, H. X.,Alam, S. M.,Kepler, T. B.,Ramesh, A.,Wiehe, K.,Holland, J. A.,Bradley, T.,V...> ;Nat Commun. 2017 Nov 25
• Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vacci...
  Easterhoff, D.,Moody, M. A.,Fera, D.,Cheng, H.,Ackerman, M.,Wiehe, K.,Saunders, K. O.,Pollara, J.,Vandergrift, N.,Parks, R.,Kim, J.,Michael, N. L.,O'Connell, R. J.,Exc...> ;PLoS Pathog.. 2017 Feb 25
• HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.
  Bradley T, Yang G, Ilkayeva O, Holl TM, Zhang R, Zhang J, Santra S, Fox CB, Reed SG, Parks R, Bowman CM, Bouton-Verville H, Sutherland LL, Scearce RM, Vandergrift N, K...> ;J. Immunol.. 2016-12-15
• Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice
  S Munir Alam, Barton F Haynes, M Anthony Moody, Robert Parks> ;The Journal of Immunology. 2016 Dec 25
• Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.
  Huang J, Kang BH, Ishida E, Zhou T, Griesman T, Sheng Z, Wu F, Doria-Rose NA, Zhang B, McKee K, O'Dell S, Chuang G, Druz A, Georgiev IS, Schramm CA, Zheng A, Joyce MG,...> ;Immunity. 2016-11-15
• Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.
  Tay MZ, Liu P, Williams LD, McRaven MD, Sawant S, Gurley TC, Xu TT, Dennison SM, Liao H, Chenine A, Alam SM, Moody MA, Hope TJ, Haynes BF, Tomaras GD> ;PLoS Pathog.. 2016-08-01
• Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.
  Kwon YD, Georgiev IS, Ofek G, Zhang B, Asokan M, Bailer RT, Bao A, Caruso W, Chen X, Choe M, Druz A, Ko S, Louder MK, McKee K, O'Dell S, Pegu A, Rudicell RS, Shi W, Wa...> ;J. Virol.. 2016-07-01
• Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques.
  Li H, Wang S, Kong R, Ding W, Lee F, Parker Z, Kim E, Learn GH, Hahn P, Policicchio B, Brocca-Cofano E, Deleage C, Hao X, Chuang G, Gorman J, Gardner M, Lewis MG, Hatz...> ;Proc. Natl. Acad. Sci. U.S.A.. 2016-06-14
• Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
  Bonsignori M, Zhou T, Sheng Z, Chen L, Gao F, Joyce MG, Ozorowski G, Chuang G, Schramm CA, Wiehe K, Alam SM, Bradley T, Gladden MA, Hwang K, Iyengar S, Kumar A, Lu X, ...> ;Cell. 2016-04-07
• Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses.
  Moody MA, Gao F, Gurley TC, Amos JD, Kumar A, Hora B, Marshall DJ, Whitesides JF, Xia S, Parks R, Lloyd KE, Hwang K, Lu X, Bonsignori M, Finzi A, Vandergrift NA, Alam ...> ;Cell Host Microbe. 2015-09-09
• Human Non-Neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses During SHIV Mucosal Infection in Rhesus Macaques
  Merlin L Robb, S Munir Alam, Andrew Chao, James Robinson, Jerome H Kim, Nelson L Michael, M A Moody, Barton F Haynes, Norman L Letvin, Feng Gao> ;PLoS One. 2015 Aug 04
• 30 citations
  Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research
  Lindsay Wieczorek, Shelly J. Krebs, Vaniambadi S. Kalyanaraman, Stephen Whitney, Sodsai Tovanabutra, Carlos G. Moscoso, Eric Sanders-Buell, Constance Williams, Bonnie ...> ;Journal of Virology. 2015 Aug 1
• Diversion of HIV-1 Vaccine–Induced Immunity by gp41-Microbiota Cross-Reactive Antibodies
  Magdalena E Sobieszczyk, Michael Keefer, S Munir Alam, Barton F Haynes, M Anthony Moody, Feng Gao> ;Science Magazine. 2015 Aug 01
• Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVA...
  Hulot SL, Korber B, Giorgi EE, Vandergrift N, Saunders KO, Balachandran H, Mach LV, Lifton MA, Pantaleo G, Tartaglia J, Phogat S, Jacobs B, Kibler K, Perdiguero B, Gom...> ;J. Virol.. 2015-06-01
• 131 citations
  Polyreactivity and Autoreactivity among HIV-1 Antibodies
  Mengfei Liu, Guang Yang, Kevin Wiehe, Nathan I. Nicely, Nathan Vandergrift, Wes Rountree, Mattia Bonsignori, S. Munir Alam, Jingyun Gao, Barton F. Haynes, Garnett Kelsoe> ;Journal of Virology. 2015 Jan 1
• Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
  Wiehe, K.,Easterhoff, D.,Luo, K.,Nicely, N. I.,Bradley, T.,Jaeger, F. H.,Dennison, S. M.,Zhang, R.,Lloyd, K. E.,Stolarchuk, C.,Parks, R.,Sutherland, L. L.,Scearce, R. ...> ;Immunity. 2014 Dec 20
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